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1 – 10 of over 11000Nur Alia Sheh Omar and Yap Wing Fen
This paper aims to review the potential application of surface plasmon resonance (SPR) in diagnosis of dengue virus (DENV-2) E-protein and the development of SPR to become an…
Abstract
Purpose
This paper aims to review the potential application of surface plasmon resonance (SPR) in diagnosis of dengue virus (DENV-2) E-protein and the development of SPR to become an alternative DENV sensor.
Design/methodology/approach
In this review, the existing standard laboratory techniques to diagnosis of DENV are discussed, together with their drawbacks. To overcome these drawbacks, SPR has been aimed to be a valuable optical biosensor for identification of antibodies to the DENV antigen. The review also includes the future studies on three-dimensional poly(amidoamine) (PAMAM) dendrimer-surface-assembled monolayer (SAM)-Au multilayer thin films, which are envisaged to have high potential sensitive and selective detection ability toward target E-proteins.
Findings
Application of SPR in diagnosis of DENV emerged over recent years. A wide range of immobilized biorecognition molecules have been developed to combine with SPR as an effective sensor. The detection limit, sensitivity and selectivity of SPR sensing in DENV have been enhanced from time to time, until the present.
Originality/value
The main purpose of this review is to provide authors with up-to-date and useful information on sensing DENV using SPR and to introduce a novel three-dimensional PAMAM-SAM-Au multilayer thin films for future research on SPR sensing applications.
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Xingxing Li, Shixi You, Zengchang Fan, Guangjun Li and Li Fu
This review provides an overview of recent advances in electrochemical sensors for analyte detection in saliva, highlighting their potential applications in diagnostics and health…
Abstract
Purpose
This review provides an overview of recent advances in electrochemical sensors for analyte detection in saliva, highlighting their potential applications in diagnostics and health care. The purpose of this paper is to summarize the current state of the field, identify challenges and limitations and discuss future prospects for the development of saliva-based electrochemical sensors.
Design/methodology/approach
The paper reviews relevant literature and research articles to examine the latest developments in electrochemical sensing technologies for saliva analysis. It explores the use of various electrode materials, including carbon nanomaterial, metal nanoparticles and conducting polymers, as well as the integration of microfluidics, lab-on-a-chip (LOC) devices and wearable/implantable technologies. The design and fabrication methodologies used in these sensors are discussed, along with sample preparation techniques and biorecognition elements for enhancing sensor performance.
Findings
Electrochemical sensors for salivary analyte detection have demonstrated excellent potential for noninvasive, rapid and cost-effective diagnostics. Recent advancements have resulted in improved sensor selectivity, stability, sensitivity and compatibility with complex saliva samples. Integration with microfluidics and LOC technologies has shown promise in enhancing sensor efficiency and accuracy. In addition, wearable and implantable sensors enable continuous, real-time monitoring of salivary analytes, opening new avenues for personalized health care and disease management.
Originality/value
This review presents an up-to-date overview of electrochemical sensors for analyte detection in saliva, offering insights into their design, fabrication and performance. It highlights the originality and value of integrating electrochemical sensing with microfluidics, wearable/implantable technologies and point-of-care testing platforms. The review also identifies challenges and limitations, such as interference from other saliva components and the need for improved stability and reproducibility. Future prospects include the development of novel microfluidic devices, advanced materials and user-friendly diagnostic devices to unlock the full potential of saliva-based electrochemical sensing in clinical practice.
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Michael Galagudza, Dmitry Korolev, Dmitry Sonin, Viktor Postnov, Garry Papayan, Ivan Uskov, Anastasia Belozertseva and Eugene Shlyakhto
Clinical outcome in patients with ischemic heart disease can be significantly improved with the implementation of targeted drug delivery into the ischemic myocardium. The purpose…
Abstract
Purpose
Clinical outcome in patients with ischemic heart disease can be significantly improved with the implementation of targeted drug delivery into the ischemic myocardium. The purpose of this paper is to review the data of recent literature and present original findings relevant to the problem of therapeutic heart targeting with use of nanoparticles.
Design/methodology/approach
For literature review, a public‐domain database (Medline) was searched using a web‐based search engine (PubMed) and the following key words: “nanoparticles”, “nanocarriers”, and “targeted drug delivery”. Experimental approaches included fabrication of carbon and silica nanoparticles, their characterization and surface modification. The acute hemodynamic effects of nanoparticle formulation as well as nanoparticle biodistribution were studied on male Wistar rats.
Findings
Carbon and silica nanoparticles are biocompatible materials that can be used as carriers for heart‐targeted drug delivery. Concepts of passive and active targeting can be applied to the development of targeted drug delivery to the ischemic myocardial cells.
Originality/value
The present paper is believed to be the first on ligand‐directed targeted drug delivery into the damaged myocardium.
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Ainur Rosyida, Suranto Suranto, Mohammad Masykuri and Margono Margono
This paper aims to examine the recipe for and standard methods of dyeing cotton fabric with natural dyes from jackfruit wood extract. The dyeing of the fabric was performed by…
Abstract
Purpose
This paper aims to examine the recipe for and standard methods of dyeing cotton fabric with natural dyes from jackfruit wood extract. The dyeing of the fabric was performed by immersion it without heating for a short time to obtain the best results.
Design/methodology/approach
The dyeing experiment using cotton fabric with jackfruit wood extract was conducted by immersion at room temperature. The independent variables studied were the mordant method, type of mordant, mordant concentration, salt concentration and dyeing pH. The dependent variables were colour strength and colour fastness to washing and rubbing. The orthogonal array L16 (45) was used in the study to obtain the optimal values for each parameter of the response variables. The multi-response signal-to-noise (MRSN) method was used to optimise the five response variables with different quality characteristics so that the best parameters could be obtained based on the highest MRSN ratio value.
Findings
The best parameters were obtained at an MRSN value of 4.5254 under A3B3C1D2E4 conditions, namely, the dyeing process with post mordant, aluminium nitrate type mordant, mordant concentration of 10 g/L, salt concentration of 15 g/L and dyeing a pH: of 10. Under these conditions, the value of K/S was obtained at 1.893, colour fastness to washing (GS: 4) and (SS: 4–5), dry rubbing (SS: 5) and wet rubbing (SS: 4–5).
Research limitations/implications
Obtaining a standard recipe and method for dyeing cotton cloth with jackfruit wood extract by immersion without heating is expected to lead to the development of natural dyes, and especially their application on an industrial scale. This standard and method can be used as technical guidelines by industry. The use of aluminum nitrate as a mordant will help achieve optimal dyeing results. The use of polyaluminium chloride (PAC) mordant, which has the potential to produce high colour strength, and papaya fruit sap, which has the capacity to increase colour fastness, still need to be developed to improve the results of natural dyes.
Practical implications
The standard recipe and dyeing method will be able to improve the results of the dyeing of cotton fabrics with natural dyes. Short immersion dyeing without heating and the optimal results obtained are the main attractions for their use by the textile/batik industry, as the process is easier and a lower cost. The results of dyeing with dark colours and good colour fastness mean the textile products are of the higher quality demanded by consumers, thereby increasing sales. This will encourage the use of and increase the need for natural dyes by industry, consequently reducing the use of synthetic dyes.
Social implications
The use of natural dyes, chemical mordant from aluminum salts, and natural mordant from papaya fruit sap in the dyeing process in the textile/batik industry in Indonesia will produce eco-textile and eco-batik products that are environmentally friendly and of high quality. This in turn will increase consumer interest and sales, meaning that the income and economy of workers in the textile industry/crafts sector will also increase. In addition, the use of natural dyes with the selection of a safe mordant (not containing heavy metals) will reduce the use of synthetic dyes, which pollute and damage the aquatic environment.
Originality/value
This study found a standard recipe and method of dyeing cotton fabric with natural dyes from jackfruit wood extracted by immersion without heating for a short time to obtain the best results. In addition, the discovery was of PAC, a new mordant which is effective in the use of natural dyes can give high colour strength to cotton fabric. In addition to the discovery of a new mordant, PAC, which has the potential to produce high colour strength, papaya fruit sap also has the capacity to increase colour fastness with the use of natural dyes from the flavonoid group.
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Nargess Yousefi-Limaee, Behzad Shirkavand Hadavand and Zahra Rahmani
Methylene blue (MB) is classified as a cationic dye which is widely used as chemical indicator, coloring agent and biological stain. The discharge of this dye to the water streams…
Abstract
Purpose
Methylene blue (MB) is classified as a cationic dye which is widely used as chemical indicator, coloring agent and biological stain. The discharge of this dye to the water streams is harmful to the human beings. For this reason, this study investigated the removal of MB from aqueous solution by hydrogel nanocomposite.
Design/methodology/approach
In experimental part, at first, ultraviolet (UV)-curable hydrogel/chitosan nanocomposite, which improves its elasticity by urethane acrylate, was synthesized and characterized by FTIR and SEM analysis. Afterward, the synthesized hydrogel nanocomposite was applied for the removal of MB and the influence of operational condition including nanocomposite loading, dye concentration, contact time and pH of solution was specified. Moreover, isotherm studies as well as kinetics survey were performed.
Findings
Langmuir, Freundlich, Brunauer, Emmett and Teller and Tempkin adsorption isotherms were assessed for the analysis of experimental data indicating the Freundlich isotherm was the best fitted one. The adsorption kinetics data was examined indicating the adsorption kinetics appropriate to pseudo-second-order kinetics model.
Originality/value
The predominant water absorption property of the UV-curable hydrogel/chitosan nanocomposite to 8.5 steps and outstanding adsorption capacity for the elimination of MB on hydrogel nanocomposite subscribed that the synthesized hydrogel could be a favorable adsorbent for simultaneous absorption of water and removal of cationic dyes.
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Swati Singh, Ankur Kaushal and Ashok Kumar
There is an immense concern in the international community about controlling the outburst of infectious diseases. An essential step towards diminishing it is the development of an…
Abstract
Purpose
There is an immense concern in the international community about controlling the outburst of infectious diseases. An essential step towards diminishing it is the development of an adequate detection system. Among the huge plethora of microorganisms which may infect the human body, Streptococcus pyogenes is important one which infects the upper respiratory tract leading to sore throat, which eventually develops into rheumatic heart disease (RHD) in the absence of timely treatment. A major process in controlling the infection is to detect it at an early stage. Hence, there is a need to develop detection tools which are both rapid and reliable.
Design/methodology/approach
Different types of diagnostic methods are available for identification, but the most commonly used are culturing, staining and rapid antigen detection tests. For better sensitivity and specificity, this review describes the development of biosensor. Compared with the current available methods, which are usually cumbersome, time-consuming and expensive, this approach features sequence specificity, cost efficiency, rapid and ease of use.
Findings
This review outlines various sensors which are available for the detection of Streptococcus pyogenes which causes human RHD. The working scheme of the sensors, their sensitivity and limitation of detection has been described in the review.
Originality/value
The review fulfills an acknowledged the need to study various sensors that are available for the detection of Streptococcus pyogenes, causing human RHD.
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The purpose of this paper is to study the correlation between different topographies and the reaction of Ulva Linza fouling species.
Abstract
Purpose
The purpose of this paper is to study the correlation between different topographies and the reaction of Ulva Linza fouling species.
Design/methodology/approach
In this research, topographies with a different method, such as hot embossing and hot pulling, were achieved, and biological analyses were done with macroalgae Ulva Linza cells. The effect of topography via local binding geometry (honeycomb size gradients) and Wenzel roughness on the settling of Ulva microorganisms was tested.
Findings
As a result, Ulva spores confirmed different reactions to a similar set of tapered microstructures that was in agreement with the results on distinct honeycombs. The local binding geometry and the Wenzel roughness factor “r” were dominant on settling of Ulva Linza spores.
Research limitations/implications
The reaction of an organism at the interface of vehicles’ substrate is powerfully affected by surface topographies.
Practical implications
The best embedment occurred on structures with bigger sizes than Ulva Linza’s spores. The density of settled spores was proportional to Wenzel roughness and the spores favour to attach to “kink sites” positions.
Social implications
Unfortunately, unpleasant aggregation of marine biofouling on marine vehicles’ surfaces, generate terrific difficulties in the relevant industry.
Originality/value
There was a sharp relationship between Wenzel roughness and settle of Ulva Linza spores. The local binding geometry and the Wenzel roughness factor “r” were dominant on settling of Ulva Linza spores.
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Haleh Sahebghalam, Ali Mohamadi Sani and Masoumeh Mehraban
This study was conducted with the aim of examining the ability of Saccharomyces cerevisiae to remove AFB1 from liquid media in order to use data in food and feed systems.
Abstract
Purpose
This study was conducted with the aim of examining the ability of Saccharomyces cerevisiae to remove AFB1 from liquid media in order to use data in food and feed systems.
Design/methodology/approach
The binding of AFB1 to Saccharomyces cerevisiae in the late exponential and early stationary phases was studied for viable, heat killed and acid killed yeast. AFB1 at concentrations (5, 10 and 20 μg/l) was added to the yeast culture (109 cfu/ml) in yeast mold broth medium and incubated at 25°C for 4, 12 and 24 hrs. The aflatoxin binding capacity of the strain was quantified by the amount of unbound AFB1 using ELISA technique.
Findings
The detoxification rate for different treatments reported as follows: acid treated cells > heat treated cells > viable cells. Also, the most reduction in AFB1 concentration happened within the first four hours of incubation with no significant increase in AFB1 binding on further incubation because of saturation of active sites in yeast cells. According to the results, either form of Saccharomyces cerevisiae (viable or nonviable) is effective in aflatoxin binding from medium and the binding has a physical nature.
Social implications
The findings reduce the public concern about aflatoxin B1 contamination in foods and feeds having high risk of aflatoxin contamination.
Originality/value
No research had been done to assess the ability of Saccharomyces cerevisiae in the mentioned forms to detoxify AFB1.
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Osama A. Hakeim, Samah A. Rashed and Hanan Diab
The present research aims to manage the formulations of pigment-based inks containing aminopropyl/vinyl/silsesquioxane (APSV) as a pigment binding agent for inkjet printing of…
Abstract
Purpose
The present research aims to manage the formulations of pigment-based inks containing aminopropyl/vinyl/silsesquioxane (APSV) as a pigment binding agent for inkjet printing of polyester as a commercial trial for the printing of polyester as a single-step process.
Design/methodology/approach
The proposed formulations incorporated APSV by using the mini-emulsion technique at a low relieving temperature under the thermal initiation or UV radiation of vinyl-terminated groups in APSV. In this study, the storage stability of inks with regard to physical properties was broadly examined. Moreover, the color performance, including colorimetric data, color fixation and fastness properties of printed fabrics was evaluated.
Findings
The results indicated that the inks containing APSV were formulated and were stable in terms of particle size, dispersion stability, surface tension and viscosity over a period of one month and for four freeze/thaw cycles. APSV successfully fixed the pigment-based inkjet inks on polyester fabric and could achieve a significantly higher color performance and degree of fixation than the formulated inks without APSV.
Research limitations/implications
It could also fulfill all the physical properties of ink prerequisites over storing and eliminating all challenges in improving the performance and utilization of inkjet printing.
Practical implications
APSV can also be used as a pigment binding agent to formulate inks for inkjet printing of polyester fabrics as the authors’ past examination for inkjet printing of polyester fabrics post-treated with APSV.
Social implications
This study eliminates the noteworthy challenges in formulating the pigment-based inks for textile applications by incorporation of a binder while keeping up the necessary viscosity profile for a specific print head.
Originality/value
This study addressed all the issues arising from the complex nature and very challenging requirements of inkjet inks.
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Lingling Meng, Xinmin Huang, Qufu Wei, Dandan Ji and Qianwen Wang
The paper aims to evaluate the influence of atmospheric environment on the conductivity of nanoscale copper films sputtered on polyester substrates; process parameters of optimal…
Abstract
Purpose
The paper aims to evaluate the influence of atmospheric environment on the conductivity of nanoscale copper films sputtered on polyester substrates; process parameters of optimal conductivity were firstly analyzed by orthogonal test scheme design, and then the surface morphology, crystal structures and conductivity of samples were performed after samples were placed in the atmospheric conditions for some time according to the optimization of process parameters.
Design/methodology/approach
Nanoscale copper films was prepared by RF (radio frequency) magnetron sputtering and low-temperature plasma technology with polyester fabrics as substrates and metal copper as targets under the conditions of low temperature and high vacuum.
Findings
The experimental results showed that copper films were broken and the continuity of samples was destroyed after 60 days, while exposed in atmospheric environment for 90 days, cracks of copper films gradually expanded, there was no change in the atomic species for samples placed in the atmospheric conditions. However, the conductivity of the samples hardly had changed with the ambient temperature, humidity and degree of water washing, which is mainly decided by the internal structures of substrates.
Originality/value
This paper has some theoretical and applicable value to the functional textile.
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