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Designing digital artifacts is not a linear, straightforward process. This is particularly true when applying a user-centered design approach, or co-design, with users who are unable to participate in the design process. Although the reduced participation of a particular user group may harm the end result, the literature on solving this issue is sparse. In this article, proxy design is outlined as a method for involving a user group as proxy users to speak on behalf of a group that is difficult to reach. The article investigates the following research question: How can roleplaying be embedded in co-design to engage users as proxies on behalf of those who are unable to represent themselves?

The article presents a design ethnography spanning three years at a cancer rehabilitation clinic, where digital artifacts were designed to be used collaboratively by nurses and patients. The empirical data were analyzed using content analysis and consisted of 20 observation days at the clinic, six proxy design workshops, 21 telephone consultations between patients and nurses, and log data from the digital artifact.

The article shows that simulated consultations, with nurses roleplaying as proxies for patients ignited and initiated the design process and enabled an efficient in-depth understanding of patients. Moreover, the article reveals how proxy design as a method further expanded the design. The study findings illustrate: (1) proxy design as a method for initiating design, (2) proxy design as an embedded element in co-design and (3) six design guidelines that should be considered when engaging in proxy design.

The main contribution is the conceptualization of proxy design as a method that can ignite and initiate the co-design process when important users are unreachable, vulnerable or unable to represent themselves in the co-design process. More specifically, based on the empirical findings from a design ethnography that involved nurses as proxy users speaking on behalf of patients, the article shows that roleplaying in proxy design is a fitting way of initiating the design process, outlining proxy design as an embedded element of co-design.

The use of social media is one of the new technological options that has been recommended as a potential new strategy for delivering high-quality, high-value cancer prevention and management services. Despite the increasing use of social media, little research has been done on the use of social media in brain tumors. Therefore, this systematic review aims to provide a comprehensive review of the use of social media in brain tumor research.

A systematic search was performed in PubMed, Scopus and Web of Science from inception to August 1, 2022. English full-text articles evaluating social media use, benefit or content in brain tumor were considered.

Sixteen documents satisfied the inclusion criteria and were included in the final analysis. Most of the included studies (n = 11/16) were conducted and published by researchers in the USA. In terms of social media platform, most studies focused on Twitter (8/16, 50%) and YouTube (8/16, 50%), followed by Facebook (6/16, 37.5%) and Instagram (4/16, 25%). Most studies (n = 7/12) analyzed the content of brain tumor information provided on social media, followed by patients’ use of social media (n = 3/12) and the quality of information on social media (n = 3/12). The other three articles also examined patient recruitment, crowdfunding and caregiver use of social media.

By identifying the use, benefits and content of social media platforms in different settings, patients, clinicians and policymakers can better benefit from harnessing the power of social media in different ways, leading to improved health-care services.

To the authors knowledge, this is the first study to systematically examine social media use, benefits and content status in brain tumors.

Malnutrition has a significant effect on the onset and progression of infective pathology. The malnutrition status in COVID-19 cases are not understood well. Prognostic Nutritional Index (PNI) is a new and detailed assessment of nutrition and inflammation cases. This study aims to investigate the effect of PNI on mortality in COVID-19 patients.

In total, 334 patients (males, 142; females, 192; 64.5 ± 12.3 years of age) with COVID-19 bronchopneumonia were enrolled in this investigation. Cases were divided into two groups with respect to survival (Group 1: survivor patients, Group 2: non-survivor patients). Demographic and laboratory variables of COVID-19 cases were recorded. Laboratory parameters were calculated from blood samples taken following hospital admission. PNI was calculated according to this formula: PNI = 5 * Lymphocyte count (10⁹/L) + Albumin value (g/L).

When the patients were assessed with respect to laboratory values, leukocytes, neutrophils, CRP, ferritin, creatinine and D-Dimer parameters were significantly lower in Group 1 patients than Group 2 patients. Nevertheless, serum potassium value, lymphocyte count, calcium and albumin values were significantly higher in Group 1 cases than in Group 2 cases. PNI value was significantly lower in Group 2 cases than in Group 1 cases (39.4 ± 3.7 vs 53.1 ± 4.6).

In this retrospective study of COVID-19 cases, it can be suggested that PNI may be a significant risk factor for mortality. In conclusion of this research, high-risk patients with COVID-19 can be determined early, and suitable medical therapy can be begun in the early duration.

This research paper aims to delve into the perceptions of health susceptibility among Iranian, Afghan and Tajik individuals hailing from asylum-seeking or refused asylum-seeking backgrounds currently residing in Finland, Norway and Sweden.

Semi-structured interviews were conducted between May and October 2022 involving a sample size of 27 participants. An adapted framework based on the health belief model along with previous studies served as a guide for formulating interview questions.

Notably influenced by cultural background, religious beliefs, psychological states and past traumatic experiences during migration journeys – before arrival in these countries till settling down – subjects’ perception of health concerns emerged significantly shaped. Additionally impacting perspectives were social standing, occupational status, personal/family medical history, lifestyle choices and dietary preferences nurtured over time, leading to varying degrees of influence upon individuals’ interpretation about their own wellness or illness.

Insights garnered throughout the authors’ analysis hold paramount significance when it comes to developing targeted strategies catering culturally sensitive health-care provisions, alongside framing policies better aligned with primary care services tailored explicitly around singular demands posed by these specific communities dwelling within respective territories.

This investigation represents one among few pioneering initiatives assessing perceptions regarding both physical and mental well-being within minority groups under examination across Nordic nations, unveiling complexities arising through intersecting factors like individual attributes mingling intricately with socio-cultural environments, thereby forming unique viewpoints towards health-care belief systems prevalent among such population segments.

Genetics, a discipline of biology, is one of the most recent and rapidly advancing disciplines in science. This study aims to present a bibliometric analysis of the genetics research output of Iranian authors, map the intellectual structure of these studies and investigate the development path of this literature and the interrelationships among the main topics.

This study searched the Web of Science database for documentation of Iranian-published genetics research published up to 2020. Further, this study used HistCite software to profile and analyze the most cited articles and references and to draw their historiographies.

A database search revealed 21,329 documents that created the study population. The highest cited publications based on the Global Citation Score (GCS) and Local Citation Score (LCS) achieved scores of 602 and 47, respectively. The publication growth rate study demonstrated consistent expansion over time. The scientific maps based on LCS and GCS had five and four clusters, respectively. Furthermore, journal articles emerged as the predominant type of publication.

The significance of this study is in its contribution to understanding the genetics research position in Iran, informing policymakers and researchers, helping scientific collaboration and its impact on public attitudes and quality of life. The results of the present study, with benefits for various groups of communities, such as policymakers, academic groups and public society, can bridge the gap between theoretical research and practical implications.

The results of this study, by helping future advancement in health care, medical genetics and disease prevention, may have a direct and indirect positive influence on the quality of life. Furthermore, it may lead to more informed discussions on health care and biotechnology as well as influencing public attitudes and perceptions.

Ultimately, this study concludes that despite the proliferation of publications in terms of quantity and complexity, especially in areas such as disease diagnosis, prevention and treatment, there remains a need for more attention to other facets of genetics such as biology and biotechnology. Iranian publications are most related to population genetics, human genetics, molecular genetics, medical genetics, genomics, developmental genetics and evolutionary genetics out of 10 branches of genetics. This study reveals patterns in scientific outputs and authorship collaborations and plays an alternative and innovative role in revealing Iranian research trends in genetics.

In recent years, Yoga practice has seen a rapid rise in popularity with many positive consequences, both physical and mental attributed to its practice. Ashtanga Yoga has been less well researched in this area and is the specific focus on this work. The aim of this study is to investigate the possible positive impact of long-term Ashtanga Yoga on psychological well-being.

In total, 213 long-term Ashtanga Yoga practitioners were asked to complete the positive emotion, engagement, relationships, meaning, accomplishment (PERMA) 23 scale (Butler and Kern, 2016) which measures psychological well-being. The values given by these individuals were then compared against a larger sample of 31,966 representative of the general population.

Scores were then compared with a PERMA data set representative of the general population (see Butler and Kern, 2016), primarily using a test of difference to compare samples. Secondly, the causal relationship between time spent in practice upon well-being scores.

Findings indicated that those individuals engaged in long-term Ashtanga Yoga practice significantly outperformed the control group on all dimensions of psychological well-being.

This work has demonstrated specific benefits to the practice of Ashtanga Yoga on psychological well-being. Yoga is a form of exercise that is now widely available across the globe, and as such, represents an accessible form of physical practice, which has important psychological benefits.

To the authors’ knowledge, this is the first work investigating differences in psychological well-being profiles using PERMA, as a function of Yoga practice.

This study aims to examine the eHealth literacy level among online health consumers (OHC) in Jordan and identified variables predicting their eHealth literacy level as well.

A quantitative study was conducted to achieve the study objectives. A purposeful sample of 262 OHC completed an electronic version of the eHealth literacy scale (eHEALS). eHEALS is the most cited scale in the literature, which includes eight items (measured on a 5-point Likert scale, ranging from strongly disagree to strongly agree).

Results showed that OHC in Jordan had a moderate level of overall eHealth literacy. Specifically, the eHEALS formed two conceptually sound factors. Gender, occupation, perceived usefulness and perceived importance of the internet, and more frequent online health information seeking were significant positive predictors of overall eHealth literacy and/or its two identified dimensions.

This study represents a humble contribution to the field. Several recommendations were suggested to maintain and improve eHealth literacy among OHC in Jordan.

The internet has changed the landscape of health information. There is an increase in the provision and availability of health information to all users. OHC should be skillful in locating, using and evaluating online health information. Although many researchers have increasingly studied the concept of eHealth literacy among various groups in the past decade, little research has been devoted to focus on eHealth literacy among OHC, particularly in Jordan.

An increasing number of images are generated daily, and images are gradually becoming a search target. Content-based image retrieval (CBIR) is helpful for users to express their requirements using an image query. Nevertheless, determining whether the retrieval system can provide convenient operation and relevant retrieval results is challenging. A CBIR system based on deep learning features was proposed in this study to effectively search and navigate images in digital articles.

Convolutional neural networks (CNNs) were used as the feature extractors in the author's experiments. Using pretrained parameters, the training time and retrieval time were reduced. Different CNN features were extracted from the constructed image databases consisting of images taken from the National Palace Museum Journals Archive and were compared in the CBIR system.

DenseNet201 achieved the best performance, with a top-10 mAP of 89% and a query time of 0.14 s.

The CBIR homepage displayed image categories showing the content of the database and provided the default query images. After retrieval, the result showed the metadata of the retrieved images and links back to the original pages.

With the interface and retrieval demonstration, a novel image-based reading mode can be established via the CBIR and links to the original images and contextual descriptions.

In addition to agriculture, energy production, and industries, potable water plays a significant role in many fields, further increasing the demand for potable water. Purification and desalination play a major role in meeting the need for clean drinking water. Clean water is necessary in different areas, such as agriculture, industry, food industries, energy generation and in everyday chores.

The authors have used the different search engines like Google Scholar, Web of Science, Scopus and PubMed to find the relevant articles and prepared this mini review.

The various stages of water purification include coagulation and flocculation, coagulation, sedimentation and disinfection, which have been discussed in this mini review. Using nanotechnology in wastewater purification plants can minimize the cost of wastewater treatment plants by combining several conventional procedures into a single package.

In society, we need to avail clean water to meet our everyday, industrial and agricultural needs. Purification of grey water can meet the clean water scarcity and make the environment sustainable.

This mini review will encourage the researchers to find out ways in water remediation to meet the need of pure water in our planet and maintain sustainability.

This paper aims to study the feasibility of proposed method to focus the electroporation ablation by mean of multi-output multi-electrode system.

The proposed method has been developed based on a previously designed electroporation system, which has the capabilities to modify the electric field distribution in real time, and to estimate the impedance distribution. Taking into consideration the features of the system and biological tissues, the problem has been addressed in three phases: modeling, control system design and simulation testing. In the first phase, a finite element analysis model has been proposed to reproduce the electric field distribution within the hepatic tissue, based on the characteristics of the electroporation system. Then, a control strategy has been proposed with the goal of ensuring complete ablation while minimizing the affected volume of healthy tissue. Finally, to check the feasibility of the proposal, several representative cases have been simulated, and the results have been compared with those obtained by a traditional system.

The proposed method achieves the proposed goal, as part of a complex electroporation system designed to improve the targeting, effectiveness and control of electroporation treatments and serve to demonstrate the feasibility of developing new electroporation systems capable of adapting to changes in the preplanning of the treatment in real-time.

The work presents a thorough study of control method to multi-output multi-electrode electroporation system by mean of a rigorous numerical simulation.