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Background: This paper examines the relationship between determinants of blood transfusion sustainability (BTS) that is master production scheduling (MPS) and blood production (BP) of Uganda. The study was founded on four objectives. The study looked at the direct relationship between MPS and the BTS, direct relationship between MPS and BP, direct relationship between BP and BTS. It also assessed how BP mediated the direct relationship between MPS and BTS. The study used a quantitative method.

Methods: A survey questionnaire was administered to collect data from 367 staff of regional blood banks and government university teaching hospital blood banks; and 213 were found to be usable. The main analysis was done using structural equation modeling.

Results: This study found that MPS had a negative and insignificant relationship with the BTS. The study found that relationship between MPS and BP was positive and significant. The study also found that relationship between BP and BTS was positive and significant. The study concluded that the effect of MPS on BTS was fully mediated by BP. It was recommended that blood banks seeking to achieve transfusion sustainability must understand the sector in which they operate. The various stakeholders in the blood supply chain ie blood banks, hospital blood banks, funding agents, ministry of health, must also integrate to enhance the transfusion sustainability. Blood banks performance measures essentially timely delivery was very critical for saving lives of patients in need of blood.

Conclusion: The study has provided a new conceptual framework that investigate the BP mediating effect on the relationship of MPS and BTS, and thus can serve as an incentive for more research to be conducted in this regard of different developing countries. The authors also proposed identifying the effect of other BP factors such as blood donor management and hospital transfusion practices on BTS.

Using the case of the Deepwater Horizon blowout in the Gulf of Mexico in 2010, I argue that the catastrophe was less an example of a low probability-high catastrophe event than an instance of socially produced risks and insecurities associated with deepwater oil and gas production during the neoliberal period after 1980. The disaster exposes the deadly intersection of the aggressive enclosure of a new technologically risky resource frontier (the deepwater continental shelf) with what I call a frontier of neoliberalized risk, a lethal product of cut-throat corporate cost-cutting, the collapse of government oversight and regulatory authority and the deepening financialization and securitization of the oil market. These two local pockets of socially produced risk and wrecklessness have come to exceed the capabilities of what passes as risk management and energy security. In this sense, the Deepwater Horizon disaster was produced by a set of structural conditions, a sort of rogue capitalism, not unlike those which precipitated the financial meltdown of 2008. The forms of accumulation unleashed in the Gulf of Mexico over three decades rendered a high-risk enterprise yet more risky, all the while accumulating insecurities and radical uncertainties which made the likelihood of a Deepwater Horizon type disaster highly overdetermined.

This paper aims to investigate the effect of L-citrulline supplementation on blood pressure (BP) in middle-aged and elderly populations.

Three electronic databases, namely, Google Scholar, PubMed and Scopus, were searched from 1990 to November 2020. Random effects model analysis was applied for quantitative data synthesis, and 6 trials with 150 participants were identified and included in the analysis.

Results showed an overall non-significant effect of L-citrulline supplementation on both systolic BP (SBP) and diastolic BP (DBP) in middle-aged and elderly participants. However, stratified analysis indicated a significant reduction in SBP (SMD: −0.41, 95% CI: −0.84, 0.02; p = 0.06, heterogeneity p = 0.41; I2 = 10%) but not in DBP (SMD:−0.15, 95% CI: −0.57, 0.28; p = 0.51, heterogeneity p = 0.60; I2 = 0%), following longer-term (= 8 weeks) supplementation of L-citrulline. Additionally, higher doses of L-citrulline (= 6 grams) showed a marginally significant reduction in DBP (SMD: −0.38, 95% CI: −0.78, 0.02; p = 0.06, heterogeneity p = 0.50; I2 = 0%).

In conclusion, a higher dosage and longer duration of supplementation with L-citrulline may have potential BP lowering effects in populations at an increased risk of hypertension

The purpose of this study was to evaluate the in vitro and in vivo effects of three varieties of Indonesian fermented rice bran (RB) (Inpari 6, Inpari 30 and Inpara 1).

Three types of RB were fermented using Rhizopus oligosporus. The total phenolic content (TPC) was determined using the Folin–Ciocalteau method, and antioxidant activity was analyzed by measuring the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity (RSA). For in vivo analyses, one week after acclimatization, stroke-prone spontaneously hypertensive rats (n = 4, 12 weeks of age) were divided into two groups and orally administered fermented RB (40 mg/kg body weight) or distilled water as a control after 16 h of fasting. Blood pressure (BP) was measured before and 2, 4 and 6 h after administration with a BP monitor without warming. Six days later, the rats were subject to the same procedure and sacrificed after 6 h of oral administration. Blood was collected and the plasma was separated to measure nitric oxide, glucose and insulin levels.

The highest TPC and RSA of fermented RB were obtained from Inpari 30 after incubation for 72 h (260.33 ± 0.39 mg GAE/100 g dry basis and 83.71 ± 0.61 per cent), respectively. Furthermore, single oral administration of fermented RB improved BP (p < 0.05) and glucose metabolism after 6 h of administration (p < 0.05).

This is the first study to evaluate the effects of fermented RB on improving high BP and glucose profiles by using a spontaneously hypertensive animal model.

This paper aims to verify the effect of 12 weeks of grape juice (GJ) consumption associated with aerobic exercise on the variation of the hypertensive elderly pressure.

A total of 45 hypertensive elderly of both sexes were distributed into: control group (CG, n = 10), exercise group (EG, n = 10), juice group (JG, n = 12) and juice and exercise group (JEG, n = 13). Blood pressure and heart rate were checked weekly before exercise in JG and JEG, and before and after intervention in all groups, with JG and JEG supplemented with 200 mL of GJ. Three weekly sessions of moderate walking were applied.

There was a reduction in EG, JG and JEG for systolic pressure and diastolic only for JG and JEG. The GJ consumption to the practice of aerobic exercise provided reductions in the arterial pressure of hypertensive, in addition to stabilization of the diastolic pressure.

Although the objective of the study was to compare the effect and value of intervention with controls, the study had no intervention in food consumption, which could have led to more significant results. There was a limitation in the control drink, leading the study not to be blind, which may have impaired the results. However, it is probably not a bias, as the groups were divided by residence area, and therefore, had no direct contact with the other groups. Another limitation was that the sample size was still small, which would lead to more reliable results. Finally, although the existing limitations cannot be disregarded, the results of this research are very promising, especially when the objective is the effect of GJ and aerobic exercise on blood pressure, with the possibility of implementing supplemental GJ and the inclusion or not of exercise to the hypertensive elderly.

The paper deals with the benefits of GJ consumption associated with aerobic physical exercise on the blood pressure of elderly hypertensive patients. Considering that GJ along with physical exercise was enough to reduce the blood pressure of hypertensive elderly, this may be a new model to be used to reduce and/or control blood pressure, and GJ and the exercise to be part of the daily life of the population.

The purpose of the present study is to evaluate chocolate consumption effects with a non invasive metodology. There is evidence that the consumption of dark chocolate and cocoa with high flavonoid content could have positive effects on blood pressure (BP) and weight management (WM); however, there are complications at the moment of obtaining blood samples to evaluate on children at a primary school level.

A total of 54 healthy scholars were included; consumption of 70 per cent cacao dark chocolate was integrated into the daily snack during a 30-day period. Blood pressure, body fat, total content of polyphenols in urine and total antioxidant capacity of saliva were measured. The results obtained were divided in relation of two groups of students, A and B, with lesser or higher difficulties to WM in a self-assessment test; variables were then statistically evaluated.

Consumption of chocolate produced changes in the total content of polyphenols (from 5.6 to 6.8 µg/mL, p < 0.016) and salivary antioxidant capacity [(14.76 ± 5.4 and 16.14 ± 3.9) TEU nmol versus. t = 0; p < 0.029 and p < 0.001 at 15 and 30 days, respectively]. Group B, which presented higher difficulties concerning WM, presented a body fat reduction of about 0.63 per cent after chocolate consumption (p = 0.045) and a diastolic blood pressure reduction of −2.8 mm Hg in average (p < 0.025). A significant weight gain (p < 0.023) was observed only in Group A.

Despite the reduced sensitivity of the non-invasive methodology, differences in urine and salivary content of polyphenols and antioxidant capacity suggest that the design used could be feasible, although extended studies are needed to corroborate it.

A non-invasive study for screening the potential health benefits of dark chocolate was assayed. The results suggest that dark chocolate consumption in children as part of the daily snack could be a complementary element in weight management and in prevention of future risk factors to chronic diseases.

Type 2 diabetes mellitus (T2DM) is a worldwide health problem. Blood pressure (BP) and inflammation are well-established risk factors for the cardiovascular complications of T2DM. Genistein is known to improve endothelial dysfunction. The purpose of this study is to investigate the effects of genistein supplementation on BP, high-sensitive C-reactive protein (hs-CRP) and homocysteine (Hcy) levels in postmenopausal women with T2DM.

This randomized, double-blind, placebo-controlled clinical trial is conducted on postmenopausal women with T2DM. A total of 54 subjects aged between 47 and 69 years are divided into two groups. Participants in the genistein group (n = 28) are given two genistein capsules (each capsule contained 54 mg genistein) and those in the placebo group (n = 26) received two placebo capsules (each capsule contained 54 mg maltodextrin) daily for 12 weeks. General characteristics, BP, hs-CRP and Hcy levels are measured at the baseline and at the end of the trial.

Genistein supplementation resulted in a significant reduction in systolic BP (SBP) (p < 0.001), diastolic BP (DBP) (p = 0.020), mean arterial pressure (MAP) (p < 0.001), serum levels of hs-CRP (p = 0.005) and Hcy (p = 0.001) in genistein group compared with placebo group at the end of the study. Significant decreases are also found in SBP by 5.4%, p < 0.001, DBP by 6.7%, p < 0.001, MAP by 6.2%, p < 0.001, serum levels of hs-CRP by 47.0%, p = 0.015 and Hcy by 18.4%, p < 0.001 in the genistein supplemented group. No significant changes are observed in terms of all post-intervention values in the placebo group.

Genistein administration improved BP, hs-CRP and Hcy levels in postmenopausal women with T2DM and may be useful in control of some CVD risk factors in these subjects.

This study illuminates how organizational actors use images in their struggle to define a contested industry. By leveraging social semiotics and visual rhetoric, we examine how multimodal texts (combining words and images) are used to label and reframe an industry using technical, environmental, human-rights, and preservation-of-life criteria. Building on theories of legitimation, we find that for this industry, contesting attempts at legitimacy work are escalated along a moral hierarchy. We offer an approach for examining how actors draw from broader meaning systems, use visual rhetoric in multimodal texts, and employ dual processes of legitimation and de-legitimation.

Metabolic syndrome (MetS) is a complex disorder that exacerbates the risk of cardiovascular disease and diabetes mellitus; some studies have indicated the beneficial effects of green tea on human health. The purpose of this study is to investigate the effects of green tea consumption on the MetS indicators in women.

A randomized clinical trial was carried out on 70 eligible women with confirmed diagnosis of MetS who visited Shabani Diabetes Clinic (Isfahan, Iran). Participants were randomly divided into two groups. Participants in the Green Tea Group were asked to consume three 200 cc of green tea in the morning, at noon and at night for eight weeks, while people in the control group were asked to take identical amount of lukewarm water at the same schedule. Anthropometric indicators, blood pressure, blood sugar, lipid profile, diet and physical activity were assessed at the beginning and the end of the study.

An independent t-test showed that weight (p = 0.001), body mass index (p = 0.001), waist circumference (p < 0.001) and waist–hip ratio (p = 0.02), systolic blood pressure (p = 0.04), fasting blood glucose (p = 0.01) and low density lipoprotein (p = 0.03) changed significantly more in the Green Tea Group than in the control group; but no such inter-group difference was observed in diastolic blood pressure, triglyceride, total cholesterol and high density lipoprotein (HDL) values (p > 0.05).

Regular consumption of green tea for eight weeks significantly improved anthropometric indices, blood pressure, blood sugar and lipid profile in women with MetS. Therefore, this beverage can serve as part of an effective dietary strategy to control MetS.

The purpose of this study is to determine the blood pressure (BP) lowing potential of some herbs used by the indigenous people of Zango Kataf, Kaduna State, Nigeria, to treat hypertension.

A total of 17 herbal healers and 15 hypertensive patients who use herbs to treat hypertension in Zango Kataf, Kaduna State, Nigeria, were consulted between 2019 and 2020. Participants were selected via purposeful sampling. BP was measured before and after the ingestion of a herbal preparation. Three plant preparations were screened: Newbouldia laevis, Hibiscus cannabinus and Pavetta crassipes.

H. cannabinus produced a significant decrease of 16, 12 and 14 mmHg in SBP at 2, 3 and 4 h, respectively (p = 0.001 at 2 h, p = 0.04 at 3 h, p = 0.01 at 4 h). While P. crassipes produced a significant decrease in SBP of 12, 15, 19 and 20 mmHg at 1, 2, 3 and 4 h, respectively (p = 0.04 at 1 h, p= 0.00 at 2 h, p = 0.00 at 3 h and p = 0.00 at 4 h). The findings for N. laevis were not reported due to incomplete information.

The sample size of this study was small. The researcher could not meet with some hypertensive clients owing to the poor cooperation of some herbal healers. Further, some hypertensive patients rejected the offer to participate in the study.

This study reveals that treatment with H. cannabinus and P. crassipes significantly decrease BP in hypertensive patients.