Search results

Atherosclerosis tends to occur in the distinctive carotid sinus, leading to vascular stenosis and then causing death. The purpose of this paper is to investigate the effect of sinus sizes, positions and hematocrit on blood flow dynamics and heat transfer by different numerical approaches.

The fluid flow and heat transfer in the carotid artery with three different sinus sizes, three different sinus locations and four different hematocrits are studied by both computational fluid dynamics (CFD) and fluid-structure interaction (FSI) methods. An ideal geometric model and temperature-dependent non-Newtonian viscosity are adopted, while the wall heat flux concerning convection, radiation and evaporation is used.

With increasing sinus size, the average velocity and temperature of the blood fluid decrease, and the area of time average wall shear stress (TAWSS)with small values decreases. As the distances between sinuses and bifurcation points increase, the average temperature and the maximum TAWSS decrease. Atherosclerosis is more likely to develop when the sinuses are enlarged, when the sinuses are far from bifurcation points, or when the hematocrit is relatively large or small. The probability of thrombosis forming and developing becomes larger when the sinus becomes larger and the hematocrit is small enough. The movement of the arterial wall obviously reduces the velocity of blood flow, blood temperature and WSS. This study also suggests that the elastic role of arterial walls cannot be ignored.

The hemodynamics of the internal carotid artery sinus in a carotid artery with a bifurcation structure have been investigated thoroughly, on which the impacts of many factors have been considered, including the non-Newtonian behavior of blood and empirical boundary conditions. The results when the FSI is considered and absent are compared.

This study aims to perform three-dimensional numerical computations for blood flow through a double stenosed carotid artery. Pulsatile flow with Womersley number (Wo) of 4.65 and Reynolds number (Re) of 425, based on the diameter of normal artery and average velocity of inlet pulse, was considered.

Finite volume method based ANSYS Fluent 20.1 was used for solving the governing equations of three-dimensional, laminar, incompressible and non-Newtonian blood flow. A high-quality grid with sufficient refinement was generated using ICEM CFD 20.1. The time-averaged flow field was captured to investigate the effect of severity and eccentricity on the lumen flow characteristics.

The results show that an increase in interspacing between blockages brings shear layer instability within the region between two blockages. The velocity profile and wall shear stress distribution are found to be majorly influenced by eccentricity. On the other hand, their peak magnitude is found to be primarily influenced by severity. Results have also demonstrated that the presence of eccentricity in stenosis would assist in flow development.

Variation in severity and interspacing was considered with a provision of eccentricity equal to 10% of diameter. Eccentricity refers to the offset between the centreline of stenosis and the centreline of normal artery. For the two blockages, severity values of 40% and 60% based on diameter reduction were permuted, giving rise to four combinations. For each combination, three values of interspacing in the multiples of normal artery diameter (D), viz. 4D, 6D and 8D were considered.

The purpose of this paper is to study haemodynamic flow characteristics and entropy analysis in a bifurcated artery system subjected to stenosis, magnetohydrodynamic (MHD) flow and aneurysm conditions. The findings of this study offer significant insights into the intricate interplay encompassing electro-osmosis, MHD flow, microorganisms, Joule heating and the ternary hybrid nanofluid.

The governing equations are first non-dimensionalised, and subsequently, a coordinate transformation is used to regularise the irregular boundaries. The discretisation of the governing equations is accomplished by using the Crank–Nicolson scheme. Furthermore, the tri-diagonal matrix algorithm is applied to solve the resulting matrix arising from the discretisation.

The investigation reveals that the velocity profile experiences enhancement with an increase in the Debye–Hückel parameter, whereas the magnetic field parameter exhibits the opposite effect, reducing the velocity profile. A comparative study demonstrates the velocity distribution in Au-CuO hybrid nanofluid and Au-CuO-GO ternary hybrid nanofluid. The results indicate a notable enhancement in velocity for the ternary hybrid nanofluid compared to the hybrid nanofluids. Moreover, an increase in the Brinkmann number results in an augmentation in entropy generation.

This study investigates the flow characteristics and entropy analysis in a bifurcated artery system subjected to stenosis, MHD flow and aneurysm conditions. The governing equations are non-dimensionalised, and a coordinate transformation is applied to regularise the irregular boundaries. The Crank–Nicolson scheme is used to model blood flow in the presence of a ternary hybrid nanofluid (Au-CuO-GO/blood) within the arterial domain. The findings shed light on the complex interactions involving stenosis, MHD flow, aneurysms, Joule heating and the ternary hybrid nanofluid. The results indicate a decrease in the wall shear stress (WSS) profile with increasing stenosis size. The MHD effects are observed to influence the velocity distribution, as the velocity profile exhibits a declining nature with an increase in the Hartmann number. In addition, entropy generation increases with an enhancement in the Brinkmann number. This research contributes to understanding fluid dynamics and heat transfer mechanisms in bifurcated arteries, providing valuable insights for diagnosing and treating cardiovascular diseases.

The development of new advanced materials, such as photopolymerizable resins for use in stereolithography (SLA) and Ti6Al4V manufacture via selective laser melting (SLM) processes, have gained significant attention in recent years. Their accuracy, multi-material capability and application in novel fields, such as implantology, biomedical, aviation and energy industries, underscore the growing importance of these materials. The purpose of this study is oriented toward the application of new advanced materials in stent manufacturing realized by 3D printing technologies.

The methodology for designing personalized medical devices, implies computed tomography (CT) or magnetic resonance (MR) techniques. By realizing segmentation, reverse engineering and deriving a 3D model of a blood vessel, a subsequent stent design is achieved. The tessellation process and 3D printing methods can then be used to produce these parts. In this context, the SLA technology, in close correlation with the new types of developed resins, has brought significant evolution, as demonstrated through the analyses that are realized in the research presented in this study. This study undertakes a comprehensive approach, establishing experimentally the characteristics of two new types of photopolymerizable resins (both undoped and doped with micro-ceramic powders), remarking their great accuracy for 3D modeling in die-casting techniques, especially in the production process of customized stents.

A series of analyses were conducted, including scanning electron microscopy, energy-dispersive X-ray spectroscopy, mapping and roughness tests. Additionally, the structural integrity and molecular bonding of these resins were assessed by Fourier-transform infrared spectroscopy–attenuated total reflectance analysis. The research also explored the possibilities of using metallic alloys for producing the stents, comparing the direct manufacturing methods of stents’ struts by SLM technology using Ti6Al4V with stent models made from photopolymerizable resins using SLA. Furthermore, computer-aided engineering (CAE) simulations for two different stent struts were carried out, providing insights into the potential of using these materials and methods for realizing the production of stents.

This study covers advancements in materials and additive manufacturing methods but also approaches the use of CAE analysis, introducing in this way novel elements to the domain of customized stent manufacturing. The emerging applications of these resins, along with metallic alloys and 3D printing technologies, have brought significant contributions to the biomedical domain, as emphasized in this study. This study concludes by highlighting the current challenges and future research directions in the use of photopolymerizable resins and biocompatible metallic alloys, while also emphasizing the integration of artificial intelligence in the design process of customized stents by taking into consideration the 3D printing technologies that are used for producing these stents.

This study aims to facilitate access to vascular disease screening for low-income individuals living in remote and conflict areas based on the results of a pilot trial in Colombia. Also, to increase the amount of diagnosis training of vascular surgery (VS) in civilians.

The operation method includes five stages: strategy development and adjustment; translation of the strategy into a real-world setting; operation logistics planning; strategy analysis and adoption. The operation plan worked efficiently in this study’s sample. It demonstrated high sensibility, efficiency and safety in a real-world setting.

The authors developed and implemented a flow model operating plan for screening vascular pathologies in low-income patients pro bono without proper access to vascular health care. A total of 140 patients from rural areas in Colombia were recruited to a controlled screening session where they underwent serial noninvasive ultrasound assessments conducted by health professionals of different training stages in VS.

The plan was designed to be implemented in remote, conflict areas with limited access to VS care. Vascular injuries are critically important and common among civilians and military forces in regions with active armed conflicts. As this strategy can be modified and adapted to different medical specialties and geographic areas, the authors recommend checking the related legislation and legal aspects of the intended areas where we will implement this tool.

Different sub-specialties can implement the described method to be translated into significant areas of medicine, as the authors can adjust the deployment and execution for the assessment in peripheral areas, conflict zones and other public health crises that require a faster response. This is necessary, as the amount of training to which VS trainees are exposed is low. A simulated exercise offers a novel opportunity to enhance their current diagnostic skills using ultrasound in a controlled environment.

Evaluating and assessing patients with limited access to vascular medicine and other specialties can decrease the burden of vascular disease and related complications and increase the number of treatments available for remote communities.

It is essential to assess the most significant number of patients and treat them according to their triage designation. This management is similar to assessment in remote areas without access to a proper VS consult. The authors were able to determine, classify and redirect to therapeutic interventions the patients with positive findings in remote areas with a fast deployment methodology in VS.

Access to health care is limited due to multiple barriers and the assessment and response, especially in peripheral areas that require a highly skilled team of medical professionals and related equipment. The authors tested a novel mobile assessment tool for remote and conflict areas in a rural zone of Colombia.

It is the expectation of Halal consumers that the meat they buy in retail shops and restaurants are ethically and legally reared and slaughtered in approved premises to protect animal welfare and public health. While this may be the case in multinational and well-established supermarkets due to due diligence on the part of retailers, there is evidence to suggest that some independent retail shops and ethnic restaurants in the UK partake in selling meat from illegally slaughtered animals. It is a crime that involves many players, but usually masterminded by rural entrepreneurs, including rogue farmers who supply the animals for illegal slaughter and further processing into smokies, or as part of the Islamic festival of Qurbani, in makeshift abattoirs. The purpose of this paper is to highlight illegal slaughter of sheep for the Halal market and how these impacts on food integrity and animal welfare.

This paper examines the legality of slaughter in accordance with UK animal welfare and food safety legislations. The documentary research approach is adopted to examine available information on the activities of organised criminal gangs in the production of smokies and their possible involvement in Qurbani fraud.

This paper demonstrates the involvement of some rogue farmers who are facilitating the smokies trade and illegal slaughter of sheep during the Qurbani sacrifice. It is worth noting that while these illegal activities occur in the Halal sector, the perpetrators are not always Muslims. The processing of illegally slaughtered sheep takes place in unhygienic conditions which is of food safety, public health concern and may violate the religious rules around slaughter.

Illegal slaughter for the Muslim sacrifice of Qurbani is underreported, this paper aims to highlight the animal welfare and food safety aspects of this type of slaughter, in addition to those slaughtered for smokies production.

At present, electrical heating clothing is widely used to keep ourselves warm at low temperature. The purpose of this paper is to explore the heat transfer performance of electrical heating fabric and the thermal comfort of human skin at low temperature.

The combined model of skin-electrical heating fabric system was established to simulate human skin tissue wearing electrical heating clothing. A series of simulation experiments are designed on the basis of verifying the effectiveness of the combined model. The temperature distribution inside the combined model and on the skin surface under different heating powers is simulated and analyzed. At the same time, the influence of ambient temperature on the thermal performance of electrical heating fabric was explored.

The skin model with blood vessels reflected the temperature change of human skin wearing electrical heating clothing. The higher the heating power of the electrical heating fabric was, the greater the temperature of the skin surface changed, the faster the temperature rose and the longer the time required to reach the stable state would be. After the heating element was electrified, it had the greatest effect on the average temperature of the epidermis and dermis, had smaller effect on the average temperature of subcutaneous layer and had little effect on the temperature of blood vessels. When the heating power was the same, the higher the ambient temperature was, the more obvious the heating effect of electrical heating fabric was. Electrical heating fabrics with different heating powers were suitable for different ambient temperature ranges.

A reasonable and effective evaluation method for the thermal comfort of electrical heating fabric was provided by establishing the skin model and combined model of the skin-electrical heating fabric system. It provides a reference for the design and application of electrical heating clothing.

A stroke is a serious, life-threatening condition that occurs when the blood supply to a part of the brain is cut off. The earlier a stroke is treated, the less damage is likely to occur. One of the methods that can lead to faster treatment is timely and accurate prediction and diagnosis. This paper aims to compare the binary integer programming-data envelopment analysis (BIP-DEA) model and the logistic regression (LR) model for diagnosing and predicting the occurrence of stroke in Iran.

In this study, two algorithms of the BIP-DEA and LR methods were introduced and key risk factors leading to stroke were extracted.

The study population consisted of 2,100 samples (patients) divided into six subsamples of different sizes. The classification table of each algorithm showed that the BIP-DEA model had more reliable results than the LR for the small data size. After running each algorithm, the BIP-DEA and LR algorithms identified eight and five factors as more effective risk factors and causes of stroke, respectively. Finally, predictive models using the important risk factors were proposed.

The main objective of this study is to provide the integrated BIP-DEA algorithm as a fast, easy and suitable tool for evaluation and prediction. In fact, the BIP-DEA algorithm can be used as an alternative tool to the LR model when the sample size is small. These algorithms can be used in various fields, including the health-care industry, to predict and prevent various diseases before the patient’s condition becomes more dangerous.

The purpose of this study is to analyze the two-dimensional blood flow in the artery slant from the axis at an angle with mild stenosis under the joint effects of the electro-osmotic, magnetic field, chemical reaction and porosity using a new analytical method. In addition, the mathematical model presented by the researchers Tripathi and Sharma (2018c) was successfully developed by adding the effect of electro-osmosis and studying the impact of the new addition in the developed model on blood flow.

A new analytical method was used to find the analytical approximate solutions of two-dimensional blood flow in artery slant from the axis at an angle with mild stenosis. This technique is based on integrating the Akbari-Ganji and the homotopy perturbation methods.

The results of axial velocity, concentration, temperature and the wall shear stress for blood flow were analyzed in the cases of the absence and presence of electro-osmosis. Furthermore, in these two states of electro-osmosis, a contour plot was created to show the difference in the profile of velocity to the flow of blood when the magnetic field was increased and the altitude of stenosis was increased. The results showed that the new technique is effective and has high accuracy to determine the analytical approximate solutions of two-dimensional blood flow in artery slant from the axis at an angle with mild stenosis. The validity, utility and necessity of the new method were illustrated from the graphs of the new solutions; in addition, there is an excellent agreement with the results of previous studies.

This paper focuses on developing the mathematical model which was presented by the researchers Tripathi and Sharma (2018c), by adding the effect of the electro-osmosis to it, which has been successfully developed. According to the authors’ modest information, the new system has not been studied before. This current problem is solved by using an innovative approach known as the Akbari-Ganji homotopy perturbation method (AGHPM) which has not been used before in two cases: the presence and absence of the effect of electro-osmosis. This new technique afford new with effective and has high accuracy results. Furthermore, the new study (i.e. adding effect of electro-osmosis) with the applications of (variable viscosity, magnetic field, chemical reaction and porosity) illustrated the importance of applying electro-osmosis and how doctors can benefit from it during surgeries through proper use.