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Article
Publication date: 5 July 2024

Majid Monajjemi and Fatemeh Mollaamin

Early prediction of any type of cancer is important for the treatment of this type of disease, therefore, our target to evaluate whether monitoring early changes in plasma human…

Abstract

Purpose

Early prediction of any type of cancer is important for the treatment of this type of disease, therefore, our target to evaluate whether monitoring early changes in plasma human epidermal growth factor receptor 2 (HER2) levels (using EIS), could help in the treatment of breast cancer or not? Human epidermal growth factor receptor 2 (HER2) overexpression is an important biomarker for treatment selection in earlier stages of cancers. The combined detection of the HER2 gene in plasma for blood cancer provides an important reference index for the prognosis of metastasis to other tissues. For this purpose, the authors fabricated and characterized a model wireless biosensor-based electrochemical impedance spectroscopy (EIS) for detecting HER2 plasma as therapeutics.

Design/methodology/approach

Most sensors generally are fabricated based on a connection between component of the sensors and the external circuits through wires. Although these types of sensors provide suitable sensitivities and also quick responses, the connection wires can be limited to the sensing ability in various devices approximately. Therefore, the authors designed a wireless sensor, which can provide the advantages of in vivo sensing and also long-distance sensing, quickly.

Findings

The biosensor structure was designed for detection of HER2, HER3 and HER-4 from lab-on-chip approach with six units of screen-printed electrode (SPE), which is built of an electrochemical device of gold/silver, silver/silver or carbon electrodes. The results exhibited that the biosensor is completely selective at low concentrations of the plasma and HER2 detection via the standard addition approach has a linearity plot, therefore, by using this type of biosensors HER2 in plasma can be detected.

Originality/value

This is then followed by detecting HER2 in real plasma using standard way which proved to have great linearity (R2 = 0.991) proving that this technique can be used to detect HER2 solution in real patients.

Open Access
Book part
Publication date: 23 September 2024

Lucy V. Piggott, Jorid Hovden and Annelies Knoppers

Sport organizations hold substantial ideological power to showcase and reinforce dominant cultural ideas about gender. The organization and portrayal of sporting events and spaces…

Abstract

Sport organizations hold substantial ideological power to showcase and reinforce dominant cultural ideas about gender. The organization and portrayal of sporting events and spaces continue to promote and reinforce a hierarchical gender binary where heroic forms of masculinity are both desired and privileged. Such publicly visible gender hierarchies contribute to the doing of gender beyond sport itself, extending to influence gender power relations within sport and non-sport organizations. Yet, there has been a relative absence of scholarship on sport organizations within the organizational sociology field. In this paper, we review findings of studies that look at how formal and informal organizational dimensions influence the doing and undoing of gender in sport organizations. Subsequently, we call for scholars to pay more attention to sport itself as a source of gendered organizational practices within both sport and non-sport organizations. We end with suggestions for research that empirically explores this linkage by focusing on innovative theoretical perspectives that could provide new insights on gender inclusion in organizations.

Details

Sociological Thinking in Contemporary Organizational Scholarship
Type: Book
ISBN: 978-1-83549-588-9

Keywords

Open Access
Article
Publication date: 28 May 2024

Emanuela Conti, Birgit Helene Jevnaker, Furio Camillo and Fabio Musso

The aim of this study was to empirically examine how much traditional attributes and green attributes characterize products within design-oriented firms. Further, we explored how…

Abstract

Purpose

The aim of this study was to empirically examine how much traditional attributes and green attributes characterize products within design-oriented firms. Further, we explored how these attributes relate to the perceived level of innovation of the firms.

Design/methodology/approach

An exploratory research was carried out in 86 Italian manufacturing companies that are members of the Industrial Design Association. Using the questionnaire method, the entrepreneurs’ perceptions have been analyzed. Data have been treated with hierarchical cluster analysis.

Findings

The analysis shows that environmental sustainability is the least important attribute of a design product and four clusters of highly design-oriented firms differ by design-product attributes. Further, the least green firms are also the least innovative in terms of incremental and general innovation.

Research limitations/implications

The small size of the sample and the provenance of firms from a single country imply limited generalizability, and further research on the topic is recommended.

Practical implications

Design-driven innovation based on traditional design attributes provides many competitive advantages to firms. However, given the growing concern about environmental challenges, investing in green attributes in design products allows for remaining competitive and more effective in innovation.

Originality/value

This study, for the first time, reveals the heterogeneity among design-oriented firms, particularly regarding the presence and assortment of traditional design attributes, as well as the incorporation of environmentally friendly attributes in their products. Moreover, the study uncovers the relationship between varying levels of green attributes in the offerings and the perception of the firm’s innovativeness.

Details

The TQM Journal, vol. 36 no. 9
Type: Research Article
ISSN: 1754-2731

Keywords

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