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Previous research indicates that vitamin D and omega-3 co-supplementation may benefit overall health, but current evidence regarding its effects on lipid profile remains unclear. The present systematic review and meta-analysis aimed to examine the effects of vitamin D and omega-3 co-supplementation on lipid profile (total cholesterol [TC], low-density lipoprotein [LDL], triglyceride [TG] and high-density lipoprotein [HDL]) in adults.

In this systematic review and meta-analysis, relevant studies were obtained by searching the PubMed, Scopus and Web of Science databases (from inception to January 2022). Weighted mean differences and 95% confidence intervals were estimated via a random-effects model. Heterogeneity, sensitivity analysis and publication bias were reported using standard methods.

Pooled analysis of six randomized controlled trials (RCTs) revealed that vitamin D and omega-3 co-supplementation yielded significant reductions in TG (p = 0.631). A pooled analysis of five trials indicated a significant association between omega-3 and vitamin D treatment and reductions in TC (p = 0.001) and LDL (p = 0.001). Although, pooled analyses of omega-3 and vitamin D did not significantly affect HDL.

The findings suggest that vitamin D and omega-3 co-supplementation lowers TG, TC and LDL in adults. Future, large-scale, RCTs on various populations are needed to elucidate further beneficial effects of vitamin D and omega-3 co-supplementation on lipid profile and establish guidelines for clinical practice.

Explains the value of Omega‐3 fatty acids in the human diet. Outlines the recommended daily amounts needed and possible sources. Explores their protective effects against heart disease and rheumatoid arthritis. Looks at recent research into the value of Omega‐3 fatty acids in infant nutrition, dermatological problems, lung disease and gastro‐intestinal disease.

Consumer interest and willingness to pay (WTP) for omega-3 enriched water buffalo mozzarella cheese are evaluated through an in-store experimental auction. The purpose of this paper is to estimate individual WTP for enriched mozzarella cheese and related it to self-efficacy beliefs and outcome expectations of omega-3 consumption, following regulatory focus theory.

Data were collected in May-June 2015 from a sample of 150 consumers in Southern Italy. A structural equation modelling procedure was implemented.

The results show a significant role is played by prevention outcome expectations on consumer behaviour. While promotion outcome expectation constructs proved non-significant, self-identity correlates with prevention outcome expectations.

There are several limitations that the authors are aware of regarding this study. First of all, since the authors rely on self-reported measures, optimistic bias might have affected participants’ responses (Weinstein, 1980). Second, results may be influenced by the choice of the specific information provided to consumers for the analysis; different claims and different information framings should be tested (LeBoeuf and Shafir, 2003).

Implications stemming from the results encourage the promotion of omega-3 enriched mozzarella cheese based on stimulating outcome expectations, bearing in mind that individual motivations should be enhanced by self-identity beliefs.

Although the combined role of self-efficacy and outcome expectations on personal intention to adopt healthy behaviour has already been demonstrated (Keller, 2006; Tudoran et al., 2012), to the best of the knowledge no previous study relates individual behaviour to an intention measured as a WTP for an actual product. In addition, current study has applied a non-hypothetical BDM (from Becker et al., 1964) auction in-store experiment.

This study aims to evaluate the knowledge and consumption of healthy foods, respectively, of oils as sources of omega-3 and dietary supplements with omega-3, among a population of young people in the center of Romania. With the objectives of identifying the factors that can influence the consumption of healthy fats and the orientation toward actions to promote less known food resources, in order to diversify the healthy food intake, the long-term improvement of the health-related effects of food.

One of the most important aspects of health is nutrition and its role in reducing the incidence of chronic diseases is supported by scientific data. In this research, the authors analyzed the level of information and the factors determining food choices with particular reference to the consumption of healthy fats and/or supplements from these fats, in order to highlight the behavior of individuals in relation to food. For this purpose, a questionnaire about food and healthy fats (omega-3) consumption and frequency was applied to the food groups of interest, along with other factors pertaining to lifestyle. The questionnaire distributed online mainly included questions related to the consumption of fats and the respondents' knowledge about them. The interest in participating in the study was manifested mainly in the young age segment. The collected data were analyzed statistically was done through Graph Pad Prism ver. 9 software with the establishment of a statistical significance threshold of 0.05.

There is a certain degree of superficiality in the knowledge of the importance and use of foods rich in omega-3. The statistically significant association has been identified both between age and the rules established in the family for observing the schedule of meals and between age and benefiting from an evaluation of the eating behavior. Statistically significant association has also been observed between the level of education and the knowledge on the health benefits of vegetable oils. The statistically significant association was also present between the level of education and the respondents' appreciation of the essential role of eating behavior in disease prevention.

Identifying the consumer profile in relation to their attitude toward healthy foods, especially fats, in order to adapt nutritional interventions with the aim to promote healthy food choices that have an impact on the health of the individual and also of the population.

Recent research has suggested the beneficial effects of omega-3 fatty acids on kidney function; however, differences in these benefits have not been well-documented with respect to different omega-3 fatty acid sources. Hence, the purpose of this study is to compare the effects of plants, marine sources of omega-3 fatty acids and their combination on biomarkers of renal function in overweight and obese individuals.

Ninety-nine overweight and obese women from a weight loss clinic received three weight-reducing diets with fish (300 g/week), walnuts (18 walnuts/week) or fish + walnuts (150 g fish + 9 walnuts/week) for 12 weeks. Serum biomarkers of renal function were measured at the beginning and the end of the intervention.

After 12 weeks, a reduction in serum creatinine was statistically higher for both the fish + walnut (−0.16 ± 0.09 mg/dL, p = 0.001) and walnut (−0.15 ± 0.05 mg/dL, p = 0.001) diets compared with the fish diet (−0.05 ± 0.04 mg/dL). A significant decrease was seen in blood urea nitrogen (BUN) level in the fish + walnut group (−0.12 ± 0.05 mg/dL, p = 0.03) and walnut group (−0.10 ± 0.04 mg/dL, p = 0.03) compared to the fish group (−0.05 ± 0.03 mg/dL). The effect of serum creatinine and BUN in the fish + walnut diet group was relatively higher than in the walnut diet group. Also, a significant difference was observed regarding weight loss in the fish + walnut diet (−7.2 ± 0.9 kg, p = 0.03) compared to in the other groups. The change in other indices was not different among the three diets.

This study found synergistic benefits of the plant and marine omega-3 fatty acids in reducing serum creatinine, BUN and weight compared with isolated marine omega-3s in overweight and obese women.

Cookies were not generally viewed as functional contributors to well-being as they are primarily perceived as confectionery products. The purpose of this paper is to evaluate the potential of flaxseed-enriched cookies as carriers of lignans and omega-3 fatty acids – functional compounds that are lacking in the western diet.

An online questionnaire collected data from Croatian consumers (n=1,035). The majority of the samples were women (73 per cent) in the age range 15-65 years (97 per cent). Most participants were employed, had a higher education degree, and lived in urban areas. Questions examined the consumption of cookies and flaxseed, interest for functional cookies, nutritional knowledge, and awareness.

Majority of subjects consumed cookies (93 per cent), while 61 per cent did not eat flaxseed or ate it less than once a month. The consumers showed elevated interest for the functional cookies with flaxseed, among which elderly women with higher nutrition awareness, and nutrition knowledge were the most interested. Functional cookies with flaxseed could be used for delivery of lignans and omega-3 fatty acids in everyday diet, but in order to reach wider range of consumers producers might benefit from employing nutritional educational marketing campaigns.

Data from the study decreased scarcity of information on consumer behaviour related to flaxseed consumption and on potential use of cookies as a functional food. Reported findings will be useful to dieticians, food industry, and food researchers in countries with a high prevalence of cookie consumption.

The purpose of this paper is to review evidence from high-quality randomised controlled trials reporting links between omega-3 enriched functional foods and health.

Using MEDLINE, a search was made for all randomised controlled trials published between 2002 and 2012 that met defined inclusion criteria. Studies had minimum durations of 28 days, clearly stated the food vehicle, dose and type of long chain omega-3 polyunsaturated fatty acids (LC3PUFA) used, and did not include studies where participants only took LC3PUFA supplements.

A total of 11 studies were located, ten of which reported potential health benefits linked to omega-3 functional food consumption. Five studies reported significant improvements in markers of cardiovascular (CV) health, while ten bioavailability studies reported increases in omega-3 blood levels when doses of 460 mg or more were integrated into food vehicles.

In the future a meta-analysis would be useful in terms of determining the dose of LC3PUFA associated with overall health benefits.

The present review concludes that omega-3 enriched functional foods are a useful way to improve LC3PUFA status and have been linked to improved health outcomes, namely markers of CV health. More work is now needed to determine whether particular population groups could benefit from consumption of these foods, for example vegetarians and children, in relation to a range of health outcomes, such as cognitive function.

This review provides evidence that integrating omega-3 enriched functional foods within the daily diet could be an effective strategy for helping to improve LC3PUFA status and attenuating CV disease risk.

Extraction and purification of Hypophthalmichthys molitrix fish oil by urea complex formation were made at −5, +1 and +5 ^○C, respectively. Omega‐3 polyunsaturated fatty acids (PUFA) have proved to be beneficial in atherosclerosis, arrhythmia and hypertriglyceridemia. Starting with the hypothesis that the observed low cardiovascular morality could be related to marine diet, which contains omega‐3 PUFA.

Fish oil was extracted by Bligh and Dyer method from the muscle tissue and after, the PUFA concentrates produced by urea complexation and the oil samples were stored at −70 ^○C. The observed results show that the rate of omega‐3 extraction has been increased while saturated and long chain monosaturated fatty acids decreased during this process.

Eicosapentaenoic acid (EPA) has a higher tendency to form urea adducts than the other two major n‐3 PUFAs, especially at low temperatures. The optimum temperature for maximum recovery of EPA is about 1 ^○C. The amount of extracted omega‐3 in H. molitrix oil were 20.58 per cent wt of total extracted oil and by subsequent purification increased to 68 per cent wt at 1 ^○C, 36.82 per cent wt at +5 ^○C and 22.53 per cent wt at −5 ^○C of total extracted oil.

Omega‐3 PUFA have proved to be beneficial in atherosclerosis, arrhythmia and hypertriglyceridemia. Starting with the hypothesis that the observed low cardiovascular morality could be related to marine diet, which contains omega‐3 PUFA. In order to reduce the risk of cardiovascular diseases, emphasis has now been placed on the increased consumption of fish and fish products which are rich in PUFA.

The amount of extracted omega‐3 in H. molitrix oil were 20.58 per cent wt of total extracted oil and by subsequent purification increased to 68 per cent wt at 1 ^○C, 36.82 per cent wt at +5 ^○C and 22.53 per cent wt at −5 ^○C of total extracted oil. Due to the low price of H. molitrix in comparison to other ocean fish sources, as well as, its availability in all seasons, higher level of ω3‐fatty acids, H. molitrix species has a good potential for ω3‐fatty acids production by extraction and subsequent purification.

There is increasing interest in the nutritional significance of fish oils, which are rich in omega‐3 fatty acids. Summarizes the background and describes a new product, “Dry n‐3(R)”, which is being used to fortify a number of different foods.

Late life depression is often associated with a poor response to antidepressants; therefore an alternative strategy for therapy is required. Although several studies have reported that phosphatidylserine (PS) may be effective for late life depression and that omega-3 fatty acids DHA and EPA have also proven beneficial for many higher mental functions, including depression, no concrete conclusion has been reached. This study was performed to clarify the effect of PS and omega-3 fatty acid-containing supplement for late life depression by not only clinical evaluation but also salivary cortisol levels. Eighteen elderly subjects with major depression were selected for the study. In all, insufficient improvement had been obtained by antidepressant therapy for at least 6 months. The exclusion criteria from prior brain magnetic resonance images (MRI) included the presence of structural MRI findings compatible with stroke or other gross brain lesions or malformations, but not white matter hypersensitivities. They took a supplement containing PS 100 mg, DHA 119 mg and EPA 70 mg three times a day for 12 weeks. The effects of the supplement were assessed using the 17-item Hamilton depression scale (HAMD17) and the basal levels and circadian rhythm of salivary cortisol. The study adopted them as indices because: salivary cortisol levels are high in patients with depression, their circadian rhythm related to salivary cortisol is often irregular, and these symptoms are alleviated as depression improves. The mean HAM-D17 in all subjects taking the supplement was significantly improved after 12 weeks of taking the supplement. These subjects were divided into 10 non-responders and 8 responders. The basal levels and circadian rhythm of salivary cortisol were normalized in the responders while not in non-responders. PS and omega-3 fatty acids, or other elements of the supplement, may be effective for late life depression, associated with the correction of basal levels and circadian rhythm of salivary cortisol.