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1 – 10 of 808Kumar S. Ray and Piyali Chatterjee
The purpose of this paper is to propose an alternative approach to approximate reasoning by DNA computing, thereby adding a new dimension to the existing approximate reasoning…
Abstract
Purpose
The purpose of this paper is to propose an alternative approach to approximate reasoning by DNA computing, thereby adding a new dimension to the existing approximate reasoning method by bringing it down to nanoscale computing. The logical aspect of approximate reasoning is replaced by DNA chemistry.
Design/methodology/approach
To achieve this goal, first the synthetic DNA sequence fuzzified by quantum dot, which is a recent advancement of nanotechnology. Thus with the help of fuzzy DNA, which holds the vague concept of human reasoning, the basic method of approximate reasoning on a DNA chip is realized. This approach avoids the tedious choice of a suitable implication operator (for a particular application) necessary for existing approximate reasoning based on fuzzy logic. The inferred consequences obtained from DNA computing‐based approximate reasoning is ultimately hybridized with appropriate complementary sequence probed on a DNA‐chip to confirm the result of inference.
Findings
The present approach is suitable for reasoning under vague and uncertain environment and does not require any subject choice of any individual expert, which is essential for existing approximate reasoning method.
Originality/value
This new tool for approximate reasoning based on DNA computing is applicable to several problems of science and engineering; namely pattern classification, control theory, weather forecasting, atmospheric science, etc.
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Kumar S. Ray and Mandrita Mondal
The purpose of this study is to develop a Turing machine or a finite automaton, which scans the input data tape in the form of DNA sequences and inspires the basic design of a DNA…
Abstract
Purpose
The purpose of this study is to develop a Turing machine or a finite automaton, which scans the input data tape in the form of DNA sequences and inspires the basic design of a DNA computer.
Design/methodology/approach
This model based on a splicing system can solve fuzzy reasoning autonomously by using DNA sequences and human assisted protocols. Its hardware consists of class IIS restriction enzyme and T4 DNA ligase while the software consists of double stranded DNA sequences and transition molecules which are capable of encoding fuzzy rules. Upon mixing solutions containing these components, the automaton undergoes a cascade of cleaving and splicing cycles to produce the computational result in form of double stranded DNA sequence representing automaton's final state.
Findings
In this work, the authors have fused the idea of a splicing system with the automata theory to develop fuzzy molecular automaton in which 1,018 processors can work in parallel, requiring a trillion times less space for information storage, is 105 times faster than the existing super computer and 1,019 power operations can be performed using one Joule of energy.
Originality/value
This paper presents a generalized model for biologically inspired computation in nano scale.
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Zhixiang Yin, Jianzhong Cui, Yan Yang, Yin Ma, Wei Wang, Jin Yang and Xia Sun
The bottleneck of current DNA computing paradigms based on brute‐force search strategy is that initial solution space grows exponentially with problem size, thus only trivial…
Abstract
Purpose
The bottleneck of current DNA computing paradigms based on brute‐force search strategy is that initial solution space grows exponentially with problem size, thus only trivial instances of NP‐complete problem can be solved. The purpose of this paper is to present a novel molecular program based on sticker models for solving dominating set problems.
Design/methodology/approach
The authors do not synthesize the initial solution pool containing every possible candidate solution as previously reported algorithm. Instead, solutions DNA molecules to the problem of interest are constructed during the course of computation.
Findings
It is shown that “exponential explosions” inherent in current DNA computing paradigms may be overcome in this way.
Originality/value
The paper proposes an error‐resistant DNA algorithm based on sticker model for solving minimum dominating problems.
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Harleen Kaur, Roshan Jameel, M. Afshar Alam, Bhavya Alankar and Victor Chang
The purpose of this paper is to ensure the anonymity and security of health data and improve the integrity and authenticity among patients, doctors and insurance providers…
Abstract
Purpose
The purpose of this paper is to ensure the anonymity and security of health data and improve the integrity and authenticity among patients, doctors and insurance providers. Simulation and validation algorithms are proposed in this work to ensure the proper implementation of the distributed system to secure and manage healthcare data. The author also aims to examine the methodology of Wireless Body Area Networks and how it contributes to the health monitoring system.
Design/methodology/approach
Wireless Body Area Network (WBAN) plays an important role in patient health data monitoring. In this paper, a novel framework is designed and proposed to generate data by the sensor machines and be stored in the cloud, and the transactions can be secured by blockchain. DNA cryptography is used in the framework to encrypt the hashes of the blocks. The proposed framework will ensure the anonymity and security of the health data and improve the integrity and authenticity among the patients, doctors and insurance providers.
Findings
Cloud Computing and Distributed Networking have transformed the IT industry and their amalgamation with intelligent systems would revolutionize the Healthcare Industry. The data being generated by devices is huge and storing it in the cloud environment would be a better decision. However, the privacy and security of healthcare data are still a concern because medical data is very confidential and desires to be safe and secure. The blockchain is a promising distributed network that ensures the security aspect of the data and makes the transactions authentic and transparent. In this work, the data is collected using various sensor devices and is transmitted to the cloud through the WBAN via the blockchain network.
Research limitations/implications
In this paper, a framework for securing and managing the healthcare data generated by intelligent systems is proposed. As the data generated by these devices are heterogeneous and huge in nature, the cloud environment is chosen for its storage and analysis. Therefore, the transactions to and from the cloud are secured by using the blockchain-based distributed network.
Practical implications
The target end-users of our system are the patients to keep themselves informed and healthy, healthcare providers to monitor the conditions of their patients virtually, and the health insurance providers to have a track of the history of the patients, so that no fraudulent claims can be made.
Originality/value
The target end-users of our system are the patients for keeping themselves informed and healthy, healthcare providers for monitoring the conditions of their patients virtually and the health insurance providers to have a track of the history of the patients, so that no fraudulent claims can be made.
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Recent developments in genetic engineering have dramatic implications for cybernetics. The possibility of rearranging the instructions on a DNA molecule to any given specification…
Abstract
Recent developments in genetic engineering have dramatic implications for cybernetics. The possibility of rearranging the instructions on a DNA molecule to any given specification is now accepted as inevitable by biologists. In this paper, we demonstrate that this opens up the possibility of using DNA and the genetic code for storing information of any kind whatsoever including computer programs. The self‐replicating nature of the double helix, its remarkable stability and its infinitessimal size offer considerable scope for the use of this molecule as a generalized means of storing information over and above its biological function in evolution.
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The purpose of this study is to investigate the use and usability of e‐books from the perspectives of users in an academic and research environment.
Abstract
Purpose
The purpose of this study is to investigate the use and usability of e‐books from the perspectives of users in an academic and research environment.
Design/methodology/approach
This study involved an e‐mail questionnaire to survey researchers in the academic and research environment of the Indian Institute of Science regarding their use of e‐books.
Findings
The responses indicated that the students tend to use this new technology more often than faculty members and staff. Those who did use e‐books mostly used reference and technical material. The highest response was from the Centre for Ecological Science, followed by the Supercomputer Education and Research Centre, and then the Department of Molecular Reproduction and Development and Genetics. The majority of the respondents have used computers for over five years for a variety of purposes including e‐mail communication, internet browsing and text processing as well as for other advanced uses such as numerical computing and DNA sequence analysis. However, the use of e‐books appears to be very low, indicating a requirement for creating awareness and user education about both software and hardware related to e‐books. Only 37 of the 104 respondents had used the free trial offer from Kluwer and Edutech eBooks during July 2004.
Originality/value
There has been no previous study reported which has investigated users' perspectives of e‐books in an academic and research environment in India using a questionnaire method.
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