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This paper aims to evaluate the effect of consumption of a high-fat diet (HFD) rich with total saturated fats on adiposity and serum levels of vascular cell adhesion molecule (sVCAM-1), a biomarker of endothelial inflammation/dysfunction. Another aim is to evaluate whether supplementation of a phytosomal formulation of curcumin would reduce adiposity measures and sVCAM-1 levels in HFD rats.

The study was conducted on 17 male rats which were allocated to one of three feeding regimen groups: normal diet (ND); HFD, or HFD with dietary phytosomal curcumin (HFD-C). Anthropometric measures were recorded weekly up to 20 weeks of feeding intervention, at the end of which, sVCAM-1 levels were also compared with one-way ANOVA and Tukey post-hoc analysis.

The HFD group had the greatest values for raw anthropometric data, and there was a group difference in anthropometric measures, however there was no significant difference between HFD and HFD-C for any measure. The gain at 20 weeks from initial values did reveal significant differences in weight and abdominal circumference between HFD and HFD-C groups. There were significant group differences in sVCAM-1 levels, with only HFD-C displaying significant lower levels than HFD group.

This is the first study that shows the capacity of a phytosomal formulation of curcumin in reducing adiposity and sVCAM-1 levels during daily intake of saturated fats above the recommended level. The results are promising in that this formulation can protect against endothelial inflammation/dysfunction, and can be used as complimentary therapy to suppress dyslipidemia/obesity-related cardiovascular complications.

This paper analyses the factors that make fashion-product crowdfunding campaigns successful. The authors argue that crowdfunding is an innovative and functional way of bringing new fashion items to the market. The purpose of this paper is to answer the question whether product innovation, lifecycle and sustainability have a positive effect on the success of fashion crowdfunding campaigns. The findings highlight that the success of the fashion crowdfunding campaigns depends on creators' adherence to the values of the platform which they use to raise capital.

A total of 300 fashion crowdfunding projects running between the 17th of October and the 15th of December 2017 were collected from Kickstarter – the world's largest crowdfunding platform based on reward-based all-or-nothing model. Two-step binomial logistic regression was used to analyse the data.

The model predicted a significant increase in the odds of success for the fashion items crowdfunded during the first-time production, and innovative and environmentally sustainable products with a higher price range of rewards. In line with previous literature, regression analyses predicted a significant effect of the control variables of goal amount (negative) and the number of rewards (positive). Contrary to previous studies, neither the presence of a video nor the campaign length predicted success.

The novel findings of this study contribute to the literature by providing an analysis of success factors of fashion items on crowdfunding platforms. The results show that innovative, environmentally sustainable and higher-priced products produced by early-stage ventures are better welcomed by the audiences.

This conceptual article presents a schematic of rat maternal behavior and niche stress epigenetic effects as a case study that is then aligned with current evolutionary concepts, which raises new questions regarding immigrant assimilation and niche dynamics.

The necessary background material for rat maternal and niche(s) stress factors are incorporated into a recursive, test-operate-test (rTOT), information-only-transfer, schematic (Patterson, 2023), which is an extension and refinement of the test-operate-test-exit (TOTE) schematic of Miller et al. (1960).

The generated epigenetic rTOT demonstrates the fundamental evolutionary unit of the flexible organism within its niche(s). The rTOT also confirms that epigenetic processes, epigenetic inheritance and phenotype plasticity are significant conceptual tools for understanding evolution. The teleology of rat adaptations for niche fitness via maternal behavior has been demonstrated. Sterling's (2011) allostasis, or predictive homeostasis, is extended to include species-niche(s) interaction(s) that are governed by recursive information feedback loops that function via self-organized criticality (SOC) for species and niche(s). Use of a rat model for biosocial issues in humans is strengthened.

Epigenetic rTOT only covers the species side of the evolutionary unit. Niche(s) require(s) a separate rTOT schematic. The information modeled does not include the entire system producing epigenetic effects but models a substantial portion of it.

Epigenetic rTOT demonstrates the utility of phenotypic plasticity, epigenetics and epigenetic inheritance as explanations for inheritable behavior patterns. rTOT is a useful computational model for evolutionary issues. The issues involved in niche modeling using an rTOT schematic are briefly reviewed.

When the demonstrated epigenetic model of rat genetics and inherited behavior are applied to the issues of immigrant enclaves, epigenetic complications for the difficulties of assimilation into the culture within which the enclaves are embedded become apparent. However, the questions raised must be addressed with extreme care to avoid cultural imperialism. Such cultural issues must be modeled with an rTOT application that covers the materials involved. The limitations of human Learning III restrictions when attempting to model Learning IV issues are addressed. Research into the means by which abuse and trauma are maintained by epigenetic means is urgently needed.

The rTOT schematic visualizes rat maternal behavior and stress epigenetic effects that produce inheritable behavior patterns, which answers Jablonka's (2017) request for new computational modeling representations. The concept of allostasis, or predictive homeostasis, (Sterling, 2011) is extended to the niche(s) of the organism under study so that allostasis becomes a fully cybernetic concept governed by SOC for both the organism and its niche(s). This new case study confirmed evolutionary effects of epigenetics, epigenetic inheritance and phenotypic plasticity. Niche control of organism evolution is presented. Epigenetic applications for immigrant assimilation issues have been suggested and niche dynamic questions have been raised.

The aim of this research study is to examine the role of emotional solidarity on religious tourism support. Data for the present research work were attained from various groups of residents in Amasya province/Türkiye.

The Google form-based questionnaires were self-managed by the participants. In the context of the survey, 306 complete questionnaires were gathered. For the data analysis, partial least squares structural equation modeling (PLS-SEM) technique was used via SmartPLS 4.0 software in conjunction with SPSS version 23.

The analysis results show that the emotional solidarity dimensions such as welcoming nature and sympathetic understanding were found to be positively related with religious tourism support at different coefficient levels; however, emotional closeness was not statistically related.

This study adds fresh insights into the field of tourist literature and has beneficial ramifications for business development in the area of religious tourism.

Industry 4.0 has received significant attention in today's competitive business market, necessitating a restructuring of functional domains in nearly every manufacturing organization. A comprehensive strategy to improve performance in preparation for Industry 4.0 implementation necessitates several steps, one of which is the establishment of performance outcomes (POs). The aim of this paper is to identify and rank the POs realized due to the adoption of Industry 4.0 enablers.

Based on an extensive literature review and inputs received from experts, a comprehensive list of enablers and the POs was prepared and finalized. This paper proposes a framework based on hybrid solution methodology, namely Neutrosophic Analytical Hierarchy Process (N-AHP) and Neutrosophic Combined Compromise Solution (N-CoCoSo), to rank the POs realized due to the adoption of Industry 4.0 enablers. The N-AHP methodology has been adopted to calculate the relative weights of the Industry 4.0 enablers. In comparison, the N-CoCoSo method has been adopted to rank the POs of Industry 4.0.

The proposed framework is applied to an Indian manufacturing organization to test the organization's practical applicability. Additionally, sensitivity analysis is also carried out to check the steadiness of the proposed framework. The findings of this study revealed that “Improved responsiveness to market conditions in today's competitive business environment” is the top-ranked PO of Industry 4.0, followed by “Enhanced competitiveness and better market share”, “Better product quality, through smart management of production process” and “Reduction in manufacturing waste and environmental sustainability” which could be realized due to adoption of its enablers.

This research would aid practitioners by enhancing the practitioners' capacity to understand and prioritize the various POs resulting from implementing Industry 4.0 enablers. Embracing a clear strategic plan will further assist practitioners in improving the efficiency of Industry 4.0 implementation.

Previous literature has only addressed the relationship between Industry 4.0 enablers and POs in a limited way. This paper attempts to compile a comprehensive list of Industry 4.0 enablers relevant to manufacturing organizations in order to fill this knowledge and research gap.

Owing to dual constraints including liability of foreignness and liability of origin when emerging multinationals internationalize, they inevitably face the challenge of overseas legitimation. However, few studies have explored how latecomers cross the threshold of legitimacy in the dynamic context of transnational operation. The purpose of this paper is to unravel the evolution process, triggers and specific strategies of overseas legitimacy threshold crossing of emerging multinationals.

Through the longitudinal case study of Haier Group and Goldwind Sci & Tech Co., Ltd, this study investigates the periodical characteristics of overseas legitimacy threshold crossings and the co-evolution among critical factors influencing the legitimation process in the host country.

First, it summarizes that the legitimacy threshold in the host country experiences a sequential process from pragmatic legitimacy to normative legitimacy, and finally cognitive legitimacy. It is an inevitable choice for emerging multinational enterprises to realize and sustain legitimation from passive adaptation to active creation. Second, it reveals that the triggers for crossing the threshold of overseas legitimacy include periodically dynamic factors – international network linkage and resource system reconfiguration, as well as cross-stage spiral interaction effects. Third, it determines the specific strategies for crossing the threshold of overseas legitimacy, namely, replacement, upgrading and reconstruction of organizational identity, and reveals the important role of insisting on the country-of-origin Facebook in promoting the legitimation.

This study enriches the legitimacy threshold crossing literature from an evolutional perspective, especially the traditional static legitimacy research. This study also reveals the key impacting factors – international network linkage and resource system reconfiguration – and their evolution process interacted with the legitimation process.

The emerging multinationals should break the stereotypes from developed markets in that only creating new cognitive patterns through active legitimate strategies can they truly cross the legitimacy threshold in the host country. The emerging multinationals also need to retain their own home country legitimacy traits – Facebook and balance the relation between the image of the home country and the image of host country.

This paper investigates the process of overseas legitimacy threshold crossing for emerging multinationals in a dynamic context of transnational operation, particularly with respect to the evolutionary role played by international network linkage and resource system reconfiguration.