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Anti‐proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower (Etlingera elatior) and turmeric leaves (Curcuma longa)

Chong Hueh Zan (Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia)
Asmah Rahmat (Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia)
Abdah Md. Akim (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia)
Norjahan Banu Mohd. Alitheen (Department of Cell Biology and Molecule, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Malaysia)
Fauziah Othman (Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia)
Gwendoline Ee Cheng Lian (Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang, Malaysia)

Nutrition & Food Science

ISSN: 0034-6659

Article publication date: 19 July 2011

Abstract

Purpose

The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines.

Design/methodology/approach

Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts (0‐100 μg/ml) using 72‐h MTT assay.

Findings

Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma), HT‐29 (colon carcinoma), MDA‐MB‐231 (non‐hormone‐dependent breast cancer), MCF‐7 (hormone‐dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC50) were obtained for MDA‐MB‐231, HepG2, HT‐29. Extracts within the concentrations of 10‐100 μg/ml were found not to be effective against proliferation of MCF‐7 and HeLa.

Originality/value

The paper shows how culinary plants – daun pandan, turmeric leaves and kantan flower displayed selective cytotoxic effects towards liver, colon and breast cancer in vitro.

Keywords

Citation

Hueh Zan, C., Rahmat, A., Abdah, , Akim, , Banu Mohd. Alitheen, N., Othman, F. and Ee Cheng Lian, G. (2011), "Anti‐proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower (Etlingera elatior) and turmeric leaves (Curcuma longa)", Nutrition & Food Science, Vol. 41 No. 4, pp. 238-241. https://doi.org/10.1108/00346651111151366

Publisher

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Emerald Group Publishing Limited

Copyright © 2011, Emerald Group Publishing Limited