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Nucleic acid testing is an effective method of accurate prevention and control and a key measure to block the spread of the epidemic. However, the fraud in nucleic acid testing occurred frequently during epidemics. This paper aims to provide a viable scheme for the government to strengthen the supervision of nucleic acid testing and to provide a new condition for the punishment for the negative act of the government and the upper limit of the reward for nucleic acid testing institution of no data fraud.

This paper formulates an evolutionary game model between the government and nucleic acid testing institution under four different mechanisms of reward and punishment to solve the issue of nucleic acid testing supervision. The authors discuss the stability of equilibrium points under the four distinct strategies and conduct simulation experiments.

The authors find that the strategy of dynamic reward and static penalty outperforms the strategies of static reward and static penalty, dynamic reward and static penalty, static reward and dynamic penalty, dynamic reward and dynamic penalty. The results reveal the appropriate punishment for the negative act of the government can enhance the positivity of the government's supervision in the strategy of dynamic reward and static penalty, while the upper limit of the reward for nucleic acid testing institution of no data fraud cannot be too high. Otherwise, it will backfire. Another interesting and counterintuitive result is that in the strategy of dynamic reward and dynamic penalty, the upper limit of the penalty for data fraud of nucleic acid testing institution cannot be augmented recklessly. Otherwise, it will diminish the government's positivity for supervision.

Most of the existing evolutionary game researches related to the reward and punishment mechanism and data fraud merely highlight that increasing the intensity of reward and punishment can help improve the government's supervision initiative and can minimize data fraud of nucleic acid institution, but they fall short of the boundary conditions for the punishment and reward mechanism. Previous literature only study the supervision of nucleic acid testing qualitatively and lacks quantitative research. Moreover, they do not depict the problem scenario of testing data fraud of nucleic acid institution regulated by the government via the evolutionary game model. Thus, this study effectively bridges these gaps. This research is universal and can be extended to other industries.

The outbreak of COVID-19 has become a major public health emergency worldwide. How to effectively guide public opinion and implement precise prevention and control is a hot topic in current research. Mining the spatiotemporal coupling between online public opinion and offline epidemics can provide decision support for the precise management and control of future emergencies.

This study focuses on analyzing the spatiotemporal coupling relationship between public opinion and the epidemic. First, based on Weibo information and confirmed case information, a field framework is constructed using field theory. Second, SnowNLP is used for sentiment mining and LDA is utilized for topic extraction to analyze the topic evolution and the sentiment evolution of public opinion in each coupling stage. Finally, the spatial model is used to explore the coupling relationship between public opinion and the epidemic in space.

The findings show that there is a certain coupling between online public opinion sentiment and offline epidemics, with a significant coupling relationship in the time dimension, while there is no remarkable coupling relationship in space. In addition, the core topics of public concern are different at different coupling stages.

This study deeply explores the spatiotemporal coupling relationship between online public opinion and offline epidemics, adding a new research perspective to related research. The result can help the government and relevant departments understand the dynamic development of epidemic events and achieve precise control while mastering the dynamics of online public opinion.

The US platelet supply is almost exclusively dependent on apheresis donors who are “aging out.” As a result, blood centers and hospitals have been experiencing spot shortages and have resorted to transfusing low-dose platelets. This paper explores using whole blood–derived platelets (WB-PLTs) to supplement the apheresis platelet (APH-PLT) supply.

This paper reviews the history leading to the current state of the US platelet supply and includes the impact of recent events such as the COVID-19 pandemic and the implementation of the US Food and Drug Administration (FDA)-mandated bacterial mitigation strategies.

WB-PLTs represent a viable source of platelets that can be used to supplement the APH-PLT supply. Whole blood automation represents a new methodology to more easily prepare WB-PLTs. Advances in donor testing and screening as well as pre-storage leukoreduction have improved the safety of WB-PLTs to the same level as APH-PLTs. Blood services in the US and abroad transfuse WB-PLTs interchangeably in all patient populations.

This paper highlights how the US blood industry is essentially “sole-sourced” in terms of APH-PLTs. In this post-COVID-19 period, when most industries are building redundancies in their supply chains, blood centers should consider WB-PLTs as an additional source of platelets to bolster the US platelet supply.

This paper aims to explore the impact of the coronavirus on the volatility spillovers of 10 selected developed markets hit by this pandemic (e.g. the USA, Canada, Korea, Japan, the UK, Germany, Italy, Spain, France and China).

The database consists of daily data from January 1, 2020, to December 31, 2022. The data used are the precise daily closing prices of various indices of selected markets gathered from the DataStream and Investing.com databases. The authors use the VAR model to study the transmission of volatility between stock markets and analyze the dynamic links between them. Then, the Granger causality test is used to study the volatility movements and determine which of these markets is likely to influence the others. Then, impulse response functions are used to understand the reactions of the studied markets following shocks in the two most important markets, namely, the American and Chinese markets. Finally, forecast errors variance decomposition is used to measure the dynamic interactions that characterize the relationships between the studied markets.

Empirical results reveal instability in the returns of various indexes and the existence of causal relationships between standardized volatility of markets. The reactions of some markets following a shock in American and Chinese markets differ among markets. The empirical results also show that forecast errors variance of some markets begin coming from their own innovations during first periods. These shares decrease then in favor of other markets interventions.

The findings have significant practical implications for governments around the world as well as for financial investors. The successful practice of China’s pandemic prevention and control efforts may inspire governments to determine how to overcome panic and strengthen confidence in victory. Policymakers can use the insights from our study to design more effective economic policies and regulations to mitigate the negative impact of future pandemics on the financial system. Regulators can use these results to identify areas of weakness in the financial system and take proactive measures to address them. Financial investors may use the outcomes of our result to better understand the impact of global pandemics on financial markets. They may know which markets are the most active, which ones are causing considerable effects on the others and which ones show resilience and an anti-risk capacity. This may help them to make appropriate decisions about their investments.

It has become imperative to estimate the impact of this pandemic on the behavior of financial markets to prevent the deterioration and dysfunction of the global financial system. The findings have important implications for financial investors and governments who should know which markets are the most shaken, which cause remarkable effects on others and which show resilience and anti-risk capacity. Countries could follow China in some measures taken to moderate the negative effects of this epidemic on national economies.

This paper investigates the impact of investor attention on the COVID-19 concept stocks in China's stock market from the perspectives of the macroeconomy, the stock market and the COVID-19 pandemic.

On the basis of controlling the time effects and individual fixed effects, this paper studies the impact of investor attention on the COVID-19 concept stocks in China's stock market through a set of fixed effect panel data models. Among them, investor attention focuses on macroeconomy, stock market and the COVID-19 pandemic, respectively, while stock indicators cover return, volatility and turnover. In addition, this paper also examines the heterogeneity influence of investor attention on the COVID-19 concept stocks from the perspective of time and stock classification.

Findings indicate that the attention to macroeconomy does not have a statistically significant effect on the return, unlike the attention to stock market and COVID-19 incident. Three types of investor attention have significant positive effects on the volatility and turnover rate. During the outbreak of the domestic epidemic, the impact of investor attention was significantly higher than that during the outbreak of the epidemic overseas. A finer-grained analysis shows that the attention to stock market has significantly increased the return of preventive type and treatment type stocks, while diagnostic-related stocks have been most affected by the attention to COVID-19 incident.

The major limitation of this work is the construction of investor attention. Although Baidu index is widely used, investor attention can be assessed more accurately based on more unstructured data. In addition, the effect of the COVID-19 can also be investigated in a longer time domain. Further research can be combined with the dynamics of the COVID-19 pandemic to more comprehensively evaluate its impact on the stock market.

The research proves that investor attention plays an important role in stock pricing and provides empirical evidence on the behavioral foundations of the conceptual sector of the stock market under uncertainty. It also has practical implications for regulators and investors interested in conducting accurate asset allocation and risk assessment.

As the current Coronavirus 2019 pandemic eases, international tourism, which was greatly affected by the outbreak, is gradually recovering. The attraction of countries to overseas tourists is related to their overall performance in the pandemic. This research integrates the data of vaccination of different countries, border control policy and holidays to explore their differential impacts on the overseas tourists’ intention during the pandemic. This is crucial for destinations to built their tourism resilience. It will also help countries and industry organizations to promote their own destinations to foreign tourism enterprises.

This study proposes an analysis based on panel data for ten countries over 1,388 days. The coefficient of variation is used to measure monthly differences of Chinese tourists’ intention to visit overseas country destinations.

Results show that, for tourist intention of going abroad: border control of the destination country has a significant negative impact; daily new cases in the destination country have a significant negative impact; domestic daily new cases have a significant positive impact; holidays have significant negative impact; daily vaccination of the destination countries has significant positive impact; and domestic daily vaccination have negative significant impact.

First, there is a large uncertainty in studying consumers’ willingness to travel abroad in this particular period because of unnecessary travel abroad caused by the control of the epidemic. Second, there are limitations in studying only Chinese tourists, and future research should be geared toward a broader range of research pairs.

First, from the government perspective, a humane response can earn the respect and trust of tourists. Second, for tourism industry, to encourage the public take vaccine would be beneficial for both the tourism destination and foreign tourism companies. The same effect can be achieved by helping tourists who are troubled by border control.

First, this research provides suggestions for the government and the tourism industry to deal with such a crisis in the future. Second, this study found that vaccination has a direct impact on tourism. This provides a basis for improving people’s willingness to vaccinate. Thirdly, this study proves suggestion for the destinations to build tourism resilience.

This study analyzes the unique control measures and vaccination in different countries during the pandemic, then provides suggestions for the tourism industry to prepare for the upcoming postpandemic tourism recovery. This study is valuable for improving the economic resilience of tourism destinations. Additionally, it helps to analyze the advantages and disadvantages of different restrain policies around the world.

Sharing and disseminating debunking information are critical to correcting rumours and controlling disease when dealing with public health crises. This study investigates the factors that influence social media users' debunking information sharing behaviour from the perspective of persuasion. The authors examined the effects of argument adequacy, emotional polarity, and debunker's identity on debunking information sharing behaviour and investigated the moderating effects of rumour content and target.

The model was tested using 150 COVID-19-related rumours and 2,349 original debunking posts on Sina Weibo.

First, debunking information that contains adequate arguments is more likely to be reposted only when the uncertainty of the rumour content is high. Second, using neutral sentiment as a reference, debunking information containing negative sentiment is shared more often regardless of whether the government is the rumour target, and information containing positive sentiment is more likely to be shared only when the rumour target is the government. Finally, debunking information published by government-type accounts is reposted more often and is enhanced when the rumour target is the government.

The study provides a systematic framework for analysing the behaviour of sharing debunking information among social media users. Specifically, it expands the understanding of the factors that influence debunking information sharing behaviour by examining the effects of persuasive cues on debunking information sharing behaviour and the heterogeneity of these effects across various rumour contexts.

This paper aims to introduce a custom-designed integrated nucleic acid detection polymerase chain reaction (PCR) instrument for clinical detection applications.

The PCR instrument can make rapid, sensitive, low-cost and quantitative molecular diagnosis compared with the current routine test flow from the pipette, series reagent to RT-PCR by manual manipulation. By integrating the multichannel automatic pipetting module, heat amplification module and real-time fluorescence detection module for the first time, the custom-designed integrated nucleic acid detection PCR instrument can achieve sample collection, subpackage, mixing, extracting, measuring and result presentation.

The multichannel automatic pipetting module was assembled with an accuracy of 0.4% (2 microliters) for accuracy measurement. Besides, the accuracy and sensitivity of nucleic acid using integrated low-cost nucleic acid detection PCR instruments were checked with COV-2019 virus (staining method) and African swine fever virus (probe method) under different concentrations.

Because of its high cost, complex system and bulky laboratory settings, including sample subpackage, mixing, extracting, measuring and finally result in presentation, the current nucleic acid detection system is not suitable for field operation and disease diagnosis in remote areas. The group independently designed and assembled an integrated low-cost multichannel nucleic acid detection PCR instrument, including a multichannel automatic pipetting module, a heat amplification module and a real-time fluorescence detection module.

The above equipment showed better reliability compared with commercial qPCR. These results can lay the foundation for functional, fast and low-cost PCR equipment for trace measurements.

This study analyzes the evolution of topics related to COVID-19 on Chinese social media platforms with the aim of identifying changes in netizens' concerns during the different stages of the pandemic.

In total, 793,947 posts were collected from Zhihu, a Chinese Question and Answer website, and Dingxiangyuan, a Chinese online healthcare community, from 31 December, 2019, to 4 August, 2021. Topics were extracted during the prodromal and outbreak stages, and in the abatement–resurgence cycle.

Netizens' concerns varied in different stages. During the prodromal and outbreak stages, netizens showed greater concern about COVID-19 news, the impact of COVID-19 and the prevention and control of COVID-19. During the first round of the abatement and resurgence stage, netizens remained concerned about COVID-19 news and the prevention and control of the pandemic, however, less attention was paid to the impact of COVID-19. During later stages, popularity grew in topics concerning the impact of COVID-19, while netizens engaged more in discussions about international events and the raising of spirits to fight the global pandemic.

This study contributes to the practice by providing a way for the government and policy makers to retrospect the pandemic and thereby make a good preparation to take proper measures to communicate with citizens and address their demands in similar situations in the future.

This study contributes to the literature by applying an adapted version of Fink's (1986) crisis life cycle to create a five-stage evolution model to understand the repeated resurgence of COVID-19 in Mainland China.

Automatic DNA-binding protein (DNA-BP) classification is now an essential proteomic technology. Unfortunately, many systems reported in the literature are tested on only one or two datasets/tasks. The purpose of this study is to create the most optimal and universal system for DNA-BP classification, one that performs competitively across several DNA-BP classification tasks.

Efficient DNA-BP classifier systems require the discovery of powerful protein representations and feature extraction methods. Experiments were performed that combined and compared descriptors extracted from state-of-the-art matrix/image protein representations. These descriptors were trained on separate support vector machines (SVMs) and evaluated. Convolutional neural networks with different parameter settings were fine-tuned on two matrix representations of proteins. Decisions were fused with the SVMs using the weighted sum rule and evaluated to experimentally derive the most powerful general-purpose DNA-BP classifier system.

The best ensemble proposed here produced comparable, if not superior, classification results on a broad and fair comparison with the literature across four different datasets representing a variety of DNA-BP classification tasks, thereby demonstrating both the power and generalizability of the proposed system.

Most DNA-BP methods proposed in the literature are only validated on one (rarely two) datasets/tasks. In this work, the authors report the performance of our general-purpose DNA-BP system on four datasets representing different DNA-BP classification tasks. The excellent results of the proposed best classifier system demonstrate the power of the proposed approach. These results can now be used for baseline comparisons by other researchers in the field.