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Online medical repositories provide a platform for users to share information and dynamically access abundant electronic health data. It is important to determine whether case report information can assist the general public in appropriately managing their diseases. Therefore, this paper aims to introduce a novel deep learning-based method that allows non-professionals to make inquiries using ordinary vocabulary, retrieving the most relevant case reports for accurate and effective health information.

The dataset of case reports was collected from both the patient-generated research network and the digital medical journal repository. To enhance the accuracy of obtaining relevant case reports, the authors propose a retrieval approach that combines BERT and BiLSTM methods. The authors identified representative health-related case reports and analyzed the retrieval performance, as well as user judgments.

This study aims to provide the necessary functionalities to deliver relevant health case reports based on input from ordinary terms. The proposed framework includes features for health management, user feedback acquisition and ranking by weights to obtain the most pertinent case reports.

This study contributes to health information systems by analyzing patients' experiences and treatments with the case report retrieval model. The results of this study can provide immense benefit to the general public who intend to find treatment decisions and experiences from relevant case reports.

Monocytes are a leukocytes’ subset that plays an important role in immunity. Protein kinase B (AKT) is involved in monocytes' survival, proliferation and differentiation. Using phorbol 12-myristate 13-acetate (PMA) as an inducer for cell line U937 differentiation into macrophage-like cells may be used as a model for cancer cell therapy or other biomedical research studies. The authors investigated the Akt1 signaling pathway's involvement with PMA as a differentiating agent and survival in the U937 cell line.

PMA was utilized to stimulate the differentiation of the U937 cell line into macrophage-like cells at a concentration of 10 nM. Akt1-phosphorylated Serine 473, Bad-phosphorylated Serine 136 and Caspase9-phosphorylated Serine 196 were tested by flow cytometry for the involvement of the Akt1 signaling pathway during differentiation in addition to the expression of CD14, CD206 and CD83. DNA cell cycle variation analysis was done using PI staining and cell viability and apoptosis detection using Annexin V and PI flow cytometry.

There was a decrease in phosphorylated Akt1 and Bad activation and an increase in Caspase9 activation, with an increase in surface markers CD14, CD206 and CD83 acquired by PMA-differentiated cells. DNA cell cycle analysis revealed cell accumulation in the G2/M phase and fewer cells in the S phase of PMA-induced U937. Apoptosis induction for Ly294002 or Wortmannin-inhibited cells and part of PMA-induced cells were detected.

These results may be used to create a model for biomedical research studies and advance the understanding of the mechanism involving differentiation of the U937 cell line.

A novel method has been proposed to reduce the false alarm rate of arrhythmia patients regarding life-threatening conditions in the intensive care unit. In this purpose, the atrial blood pressure, photoplethysmogram (PLETH), electrocardiogram (ECG) and respiratory (RESP) signals are considered as input signals.

Three machine learning approaches feed-forward artificial neural network (ANN), ensemble learning method and k-nearest neighbors searching methods are used to detect the false alarm. The proposed method has been implemented using Arduino and MATLAB/SIMULINK for real-time ICU-arrhythmia patients' monitoring data.

The proposed method detects the false alarm with an accuracy of 99.4 per cent during asystole, 100 per cent during ventricular flutter, 98.5 per cent during ventricular tachycardia, 99.6 per cent during bradycardia and 100 per cent during tachycardia. The proposed framework is adaptive in many scenarios, easy to implement, computationally friendly and highly accurate and robust with overfitting issue.

As ECG signals consisting with PQRST wave, any deviation from the normal pattern may signify some alarming conditions. These deviations can be utilized as input to classifiers for the detection of false alarms; hence, there is no need for other feature extraction techniques. Feed-forward ANN with the Lavenberg–Marquardt algorithm has shown higher rate of convergence than other neural network algorithms which helps provide better accuracy with no overfitting.

Contrary to want-based services, customer participation has got lesser attention in high-credence services like health care. Customer participation for patients with chronic illnesses could be life-threatening and goes beyond the service organization’s physical environment. Realizing the importance of transformative service research in health-care services, this study aims to propose and validate the conceptualization of customer participation for patients with chronic illnesses.

The study uses sequential exploratory research design with mixed method research. The first phase is a qualitative exploration of the nature and meaning of customer participation by synthesizing theory and insights from semi-structured interviews (N = 75) with doctors, patients and paramedical staff. Next, survey data (N = 690) of patients with chronic illnesses is used to validate the proposed conceptualization. Finally, nomological validity was also tested on an additional survey data set (N = 362) using SEM and FsQCA.

The findings reveal that health-care customer participation is a three-dimensional behavioral construct in which a customer can participate by sharing information, involving in decision-making and ensuring compliance. The study also demonstrates that customer participation is a critical driver of satisfaction with life and perceived control on illness.

The research provides policy guidelines for owners and operators of health-care organizations in developing frameworks for collecting participation data, which can be used in strategies for seeking customer participation.

The research conceptualizes and validates “customer participation” as a multidimensional higher-order construct for patients with chronic illnesses, rarely focused in services marketing and management research on health care.

This study aims to explore worldwide innovative solutions that have been proposed to mitigate the effects of COVID-19 pandemic on people’s mental health.

A qualitative methodology is adopted, which performs an exploratory study considering the innovative projects identified by the Observatory for Public Sector Innovation framework. Additionally, the analysis of the relevance and characteristics of these projects are explored considering a multidimensional framework composed of five dimensions: novelty level; social need; improvement of society; sector neutrality; and level of emergence.

The findings reveal that the number of projects in the field of mental health is low, despite their strong relevance to their communities. These projects arise from a strong social need to protect especially the most vulnerable groups in this pandemic and involve a large number of partners in the public sector, business and civil society. The role of volunteering in the revitalization and growth of these initiatives is also recognized.

This study is relevant in both the theoretical and practical dimensions. It allows the exploration of these projects considering the dimensions of social innovation and offers practical implications that allow these projects to be replicated in other countries and regions.

Perceptions of ageing towards the self and towards others can positively and negatively impact an older adult’s mental wellbeing. This paper aims to consolidate literature examining the relationship between perceptions of ageing and depression in older adults to inform both practice and policy for older adult mental health services.

Quantitative research articles examining perceptions of ageing and depression in older adults were identified through searches on three electronical databases, alongside forward and backwards citation searches. A total of 14 articles involving 31,211 participants were identified.

Greater negative attitudes towards ageing were associated with higher levels of depressive symptoms and greater positive attitudes towards ageing were associated with lower levels of depressive symptoms or higher levels of happiness. However, the causal direction of this relationship could not be determined. Studies demonstrated that perceptions of ageing also act as a moderator in the relationship between depression and health status, hopelessness and personality traits. Future research should attempt to examine the relationship between perceptions of ageing and depression in older adults to attempt to identify the causal direction of this relationship.

This is the only systematic review the authors are aware of consolidating literature which explores the relationship between older adults’ perceptions of ageing and depression. It is hoped that these findings will be able to inform both policy and practice to improve older adults’ care and support for depression.

This paper aims to explore the intention to adopt the Metaverse in Islamic banks, with a particular focus on evaluating perceived usefulness, ease of use, user satisfaction and the influence of religiosity. Integrating the technology adoption model (TAM) and religiosity intention model, this study will dissect the multidimensional aspects influencing the acceptance of Metaverse technologies.

Surveying Islamic bank professionals in Jordan, this study used a structured questionnaire and data augmentation to analyze Metaverse adoption factors. Using partial least squares-structural equation modeling, the relationships between ease of use, usefulness, religiosity and satisfaction were explored.

The study identifies pivotal relationships among perceived usefulness, ease of use, user satisfaction and religiosity in the context of adopting metaverse technologies in Islamic banks in Jordan. Evidence highlights the dominant role of perceived usefulness and ease in influencing both intention to use and satisfaction levels. Religiosity, while not a direct influencer, plays a collaborative role, underscoring a balanced mix of technological and religious elements that will potentially shape the adoption trajectory of metaverse technologies within this specific banking sector.

Integrating metaverse technologies in Islamic banks necessitates balancing technological advances with Sharia compliance. The study underscores the importance of aligning user experience with religious values and fostering innovation within Islamic ethical guidelines.

This study uniquely integrates the TAM and religiosity-intention model to explore metaverse adoption in Islamic banks, unveiling a nuanced interplay between technology and religious values. It offers practical insights for tailoring innovations in the Islamic financial ecosystem.

The textile sector is one of the sectors where competition is intense and requires the production of high-value-added products. This study aims to conduct patent analysis to find the technology status, recent trends, applications and technological evaluations of protective textile technologies in practice.

More than 36,840 patent documents related to protective textile technologies are available for researchers, patent examiners and patent researchers. Patent analysis is conducted to report the technology status, recent trends and applications of protective textile technologies. This analysis provides insights into the possible future directions of protective textile technologies in practice. Additionally, association rule mining (ARM) is performed to find the hidden patterns among protective textile technologies.

The development of protective textile technologies is revealed by the technology evaluation in this study. In addition, the sub-technology classes affecting protective textile technologies are examined using the cooperative patent classification (CPC) codes of the patent documents. Technology status and recent trends of protective textile technologies are provided in detail. The results of this study show that (1) protective textile technologies are constantly being developed, (2) the working areas of medical protective textiles are increasing, (3) there are frequent studies on fabric structures for saving lives within the framework of human needs and (4) there are four technology classes, namely A41D, Y10T, B32B and A62B impacting the other technology classes related to textile technologies such as D10B, Y10T, F41H, A62D, D04H, Y10S and D10B.

To have a competitive advantage in the marketplace, evaluation of textile technologies is critical in developing “functionalized” and “technologized” textile products. In particular, evaluating technologies in developing protective textile products is extremely important to meet customer demands and present competitive products in the market. Examining these patents for technology developers, decision-makers and policymakers is an urgent and necessary job. However, studies examining the development of protective textile technologies with patent analysis are very limited in the literature. To fill this gap, technology status, recent trends and applications of protective textile technologies are reported based on patent analysis and ARM in this study.

The authors contribute to the literature on leadership by investigating how characteristics of principal investigators (PIs) affect innovation performance, and how collaborative and non-collaborative projects moderate this relationship within the context of inter-organisational research projects.

The authors analysed panel data from the National Science and Technology Information Service on 171 research projects within a biomedical and regenerative medicines programme overseen by the Korea Health Industry Development Institute. The authors used a hierarchical regression model, based on the ordinary least squares method, to examine the relationship between PI characteristics and performance, considering both quantity and quality.

The results show that the characteristics of PIs have diverse effects on the quantity and quality of innovation performance. Gender diversity within PIs negatively affects the quality of innovation performance, while the capacity of PIs positively influences it. Moreover, the degree of PI’s engagement is positively associated with the quantity of innovation performance but does not have a significant relationship with the quality of performance. In terms of moderating effects, collaborative projects with multiple leaders seem less reliant on PI capacity than non-collaborative projects led by a single leader, in terms of innovation performance.

The results contribute significantly to the literature on innovation management by examining the role of leadership in collaborative environments to enhance innovation performance, addressing the need for empirical evidence in this area. Analyses of PI characteristics in government R&D management can lead to improved team performance, more efficient processes and effective resource allocation, ultimately fostering innovation.

Effective communication is crucial in the medical field where different stakeholders use various terminologies to describe and classify healthcare concepts such as ICD, SNOMED CT, UMLS and MeSH, but the problem of polysemy can make natural language processing difficult. This study explores the contextual meanings of the term “pattern” in the biomedical literature, compares them to existing definitions, annotates a corpus for use in machine learning and proposes new definitions of terms such as “Syndrome, feature” and “pattern recognition.”

Entrez API was used to retrieve articles form PubMed for the study which assembled a corpus of 398 articles using a search query for the ambiguous term “pattern” in the titles or abstracts. The python NLTK library was used to extract the terms and their contexts, and an expert check was carried out. To understand the various meanings of the term, the contextual environment was analyzed by extracting the surrounding words of the term. The expert determined the appropriate size of the context for analysis to gain a more nuanced understanding of the different meanings of the term pattern.

The study found that the categories of meanings of the term “pattern” are broader in biomedical publications than in common definitions, and new categories have been emerging from the term's use in the biomedical field. The study highlights the importance of annotated corpora in advancing natural language processing techniques and provides valuable insights into the nuances of biomedical language.

The study's findings demonstrate the importance of exploring contextual meanings and proposing new definitions of terms in the biomedical field to improve natural language processing techniques.