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The purpose of this paper is to propose a comprehensive theoretical framework to explain the different diffusion dynamics of a technology realized under an open source (OS) regime vs a technology realized under a closed-proprietary (CP) regime.

Following a systematic combining approach, theoretical predictions derived from literature on diffusion of innovation and on open innovation were matched with empirical observations derived from a case study of two mobile operation systems, which were released under different technological regimes.

This paper proposes a theoretical framework and a set of original theoretical propositions that can help to explain the differences in the diffusion dynamics of technologies that are released under different regimes (i.e. CP vs OS).

This paper provides managers a better understanding of the diffusion dynamics of technologies released according to an open innovation strategy. In addition, the empirical case study improves the understanding of an important industry (the MOS industry) that has not been fully investigated from the innovation diffusion perspective. Nevertheless, the efficacy and generalizability of the theoretical framework proposed in this paper require future empirical tests.

This paper makes an original contribution to the open innovation and innovation diffusion literature by linking, in a conceptual model, three antecedents of the diffusion of a new technology that previous literature has considered only separately: the regime under which the technology is released (OS vs CP), the contingencies related to the characteristics of the technology and to the network of its adopters, and the resulting barriers to adoption.

The purpose of this paper is to analyze the impact of patenting on the performance of academic spin-off firms (ASOs) in the post-creation stage. Specifically, our study analyses how the combination of knowledge transfer mechanisms by ASOs and patents can foster ASOs’ early growth performance.

The authors explored the relations between patenting processes and spin-off performance through econometric methods applied to a broad sample of Italian ASOs. The research adopts a deductive approach, and the hypotheses are tested using panel data models by considering the sales growth rate as the dependent variable regressed over measures of patenting activity and quality and assuming that firm-specific unobservable drivers of growth are captured by random effects.

The empirical analysis shows that the incorporation of knowledge transferred by the parent university and academic founders through patents affects the performance of ASOs. Specifically, the authors find that the number of patents is a positive driver of ASOs’ performance, whilst patent age does not have a significant impact on growth. Moreover, spin-offs with a larger endowment of patents obtained before foundation, surprisingly, grow less on average.

The findings have implications for ASO founders by suggesting that patenting processes reap benefits. However, in the trade-off of external knowledge access vs internal knowledge protection, it may be better to begin patenting after the foundation of ASOs.

The authors enrich the on-going debate about the connections between knowledge transfer and organizational performance. This paper combines the concepts of patents and ASOs by providing evidence on the role of patenting processes as a transfer mechanism of explicit knowledge in ASOs. Furthermore, the authors contribute to the literature on costs and benefits of patents by hinting at unexpected findings.

The purpose of this paper is to combine studies that describe the spin-off creation process with studies that analyze spin-off determinants to understand the phenomenon of spin-off development.

This paper proposes a theoretical framework to improve our understanding of academic spin-off development in southern Italy. Following a systematic combining approach, the framework is constructed by iteratively matching the concepts derived by the literature on spin-off processes and spin-off determinants with the empirical findings obtained through a case study of 19 spin-offs in southern Italy.

The combination of empirical results and literature analysis helps us to identify a general model for spin-off creation that could be particularly useful to explain the criticalities of their development.

This paper provides implications for policy-makers in southern Italy regarding factors for which intervention would support the creation of new spin-offs. This study also provides useful implications for policy-makers in other contexts, such as areas that may or may not be at a disadvantage.

The resulting framework represents an original contribution to the literature because it: links two aspects – the stages of spin-off creation and determinants of spin-off development – which are often considered separately in existing studies; explores factors that either impede or facilitate the different stages of spin-off development; provides a series of findings that can be successively tested in other studies; and sheds more light on the context of southern Italy, which has been investigated in only a limited number of previous studies.

The paper aims to explore the nature of initiatives and strategies of inter-organizational cooperation to cross the valley of death in the biopharma industry.

The authors conducted an exploratory case study analysis in the Biopharma Innovation Ecosystem in Greater Boston Area (USA), which is one of the oldest, and most successful IE in the US, specialized in the Biopharma domain, by conducting a round of expert interviews with key informants in the area, chosen as representatives of the different types of actors engaged in the drug development processes at different stages.

Main findings suggest that cooperation can contribute to surviving the valley of death by reducing the barriers within the drug development pipeline through the promotion of strategic relationships among actors of different nature, including the establishment of government-led thematic associations or consortia, agreements between university and business support structures, proximity to venture capitalist and the promotion of a general culture of academic entrepreneurship within universities.

The authors believe that this paper contributes to the literature by shedding light on the nature of the specific cooperative initiative the barriers in drug development and help to survive the valley of the death.

The purpose of this paper is aimed at analysing the influence of the host government policies on foreign direct investment (FDI) knowledge spillovers.

Starting from the analysis of the literature, the paper has introduced a theoretical model that has been illustrated analyzing the Iranian case.

Governments can promote the realisation of knowledge spillovers only if they create the conditions for improving the absorptive capacity of local firms and the connections between local firms and foreign investors (strategic approach). Moreover, in many emerging countries, governments are directly involved in relationships with foreign investors through state‐owned companies. According to this, the Iranian case shows how the direct government involvement, if it is matched with a strategic approach, can encourage the realization of FDI knowledge spillovers.

The paper presents some limitations: other quadrants of the proposed model need to be further explored adopting other case studies; moreover, the Iranian case can be examined more in deep.

From a policymaker's point of view, the paper is an useful tool because it gives them many suggestions about what FDIs attraction policies have to be adopted in order to realize FDI knowledge spillovers.

From a theoretical point of view, the paper gives a contribution to the literature on FDI spillovers highlighting the direct relationships between host government policies and FDI knowledge spillovers, especially revaluing the opportunities stemming from a direct government intervention. Moreover, this paper contributes to increase the knowledge on the Iranian context often neglected by international management studies.