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The US platelet supply is almost exclusively dependent on apheresis donors who are “aging out.” As a result, blood centers and hospitals have been experiencing spot shortages and have resorted to transfusing low-dose platelets. This paper explores using whole blood–derived platelets (WB-PLTs) to supplement the apheresis platelet (APH-PLT) supply.

This paper reviews the history leading to the current state of the US platelet supply and includes the impact of recent events such as the COVID-19 pandemic and the implementation of the US Food and Drug Administration (FDA)-mandated bacterial mitigation strategies.

WB-PLTs represent a viable source of platelets that can be used to supplement the APH-PLT supply. Whole blood automation represents a new methodology to more easily prepare WB-PLTs. Advances in donor testing and screening as well as pre-storage leukoreduction have improved the safety of WB-PLTs to the same level as APH-PLTs. Blood services in the US and abroad transfuse WB-PLTs interchangeably in all patient populations.

This paper highlights how the US blood industry is essentially “sole-sourced” in terms of APH-PLTs. In this post-COVID-19 period, when most industries are building redundancies in their supply chains, blood centers should consider WB-PLTs as an additional source of platelets to bolster the US platelet supply.

With the appearance of additional review functionality on e-commerce platforms emotional changes in composite reviews have become more diverse. How consumers process the emotional changes in composite reviews is an important concern for companies. This study investigates the impact of explores how changes in the emotional valence and emotional intensity of composite reviews on consumers' information adoption.

Based on emotion as social information theory, this study constructs a double mediation model of how the change in emotional valence of composite reviews affects consumers' adoption intention and examines the moderating effect of the dynamic change of emotional intensity. One field and three online experiments were conducted to test the proposed hypotheses.

Consumers were more likely to adopt positive–negative composite reviews than negative–positive composite reviews. Compared to negative–positive composite reviews, positive–negative composite reviews led to higher perceived empathy and lower motivational suspicion, which, in turn, led to higher information adoption. Moreover, dynamic changes in emotional intensity played a moderating role in this effect. Interestingly, the amount of attribute difference changed the differences in perceived empathy and motivated consumer suspicion generated by the composite review when considering the reviewer’s attribute difference description.

The findings have important theoretical contributions that deepen business and consumer understanding of the impact of composite reviews and have practical implications for improving the management of composite reviews by businesses.

This paper aims to introduce a custom-designed integrated nucleic acid detection polymerase chain reaction (PCR) instrument for clinical detection applications.

The PCR instrument can make rapid, sensitive, low-cost and quantitative molecular diagnosis compared with the current routine test flow from the pipette, series reagent to RT-PCR by manual manipulation. By integrating the multichannel automatic pipetting module, heat amplification module and real-time fluorescence detection module for the first time, the custom-designed integrated nucleic acid detection PCR instrument can achieve sample collection, subpackage, mixing, extracting, measuring and result presentation.

The multichannel automatic pipetting module was assembled with an accuracy of 0.4% (2 microliters) for accuracy measurement. Besides, the accuracy and sensitivity of nucleic acid using integrated low-cost nucleic acid detection PCR instruments were checked with COV-2019 virus (staining method) and African swine fever virus (probe method) under different concentrations.

Because of its high cost, complex system and bulky laboratory settings, including sample subpackage, mixing, extracting, measuring and finally result in presentation, the current nucleic acid detection system is not suitable for field operation and disease diagnosis in remote areas. The group independently designed and assembled an integrated low-cost multichannel nucleic acid detection PCR instrument, including a multichannel automatic pipetting module, a heat amplification module and a real-time fluorescence detection module.

The above equipment showed better reliability compared with commercial qPCR. These results can lay the foundation for functional, fast and low-cost PCR equipment for trace measurements.

Milk is often referred to as the ultimate food because it meets the nutritional needs of infants, children and adults alike. It is a rich source of protein, fat, sweetness, vitamins and minerals. Because of its widespread usage as a healthy dairy product, the issue of milk adulteration is of global significance. The increasing frequency of fraudulent methods in the dairy business raises concerns about its purity and quality.

A study was conducted and reviewed that looked at several approaches for detecting milk adulteration during the past 15 years. This study examines the current state of research and analyzes recent advances in development.

There are ways and technology available that can effectively put an end to the abhorrent practice of milk adulteration.

This research takes a unique approach, focusing on the application of milk adulteration. It provides an overview of milk adulteration detection and investigates the effectiveness of biosensors in identifying common milk adulterants.

This study aims to study the distribution characteristics of antibiotic resistance in direct-eating food and analysis of Citrobacter freundii genome and pathogenicity. Residual antibiotics and antibiotic resistance genes (ARGs) in the environment severely threaten human health and the ecological environment. The diseases caused by foodborne pathogenic bacteria are increasing daily, and the enhancement of antibiotic resistance of pathogenic bacteria poses many difficulties in the treatment of disease.

In this study, six fresh fruits and vegetable samples were selected for isolation and identification of culturable bacteria and analysis of antibiotic resistance. The whole genome of Citrobacter freundii isolated from cucumber was sequenced and analyzed by Oxford Nanopore sequencing.

The results show that 270 strains of bacteria were identified in 6 samples. From 12 samples of direct food, 2 kinds of probiotics and 10 kinds of opportunistic pathogens were screened. The proportion of Citrobacter freundii screened from cucumber was significantly higher than that from other samples, and it showed resistance to a variety of antibiotics. Whole genome sequencing showed that Citrobacter freundii was composed of a circular chromosome containing signal peptides, transmembrane proteins and transporters that could induce antibiotic efflux, indicating that Citrobacter freundii had strong adaptability to the environment. The detection of genes encoding carbohydrate active enzymes is more beneficial to the growth and reproduction of Citrobacter freundii in crops. A total of 29 kinds of ARGs were detected in Citrobacter freundii, mainly conferring resistance to fluoroquinolones, aminoglycosides, carbapenem, cephalosporins and macrolides. The main mechanisms are the change in antibiotic targets and efflux pumps, the change in cell permeability and the inactivation of antibiotics and the detection of virulence factors and ARGs, further indicating the serious risk to human health.

The detection of genomic islands and prophages increases the risk of horizontal transfer of virulence factors and ARGs, which spreads the drug resistance of bacteria and pathogenic bacteria more widely.

In large-scale group decision-making (LSGDM) situations, existing TODIM group decision-making methods often fail to account for the influence of social network relationships and the bounded rationality of decision-makers (DMs). To address this issue, a new TODIM-based group decision-making method is proposed that considers the current trust relationships among DMs in a large-scale trust relationship network.

This method consists of two main stages. In the first stage, the large-scale group is partitioned into several sub-clusters based on trust relationships among DMs. The dominance degree matrix of each sub-cluster is then aggregated into the large-scale group dominance degree. In the second stage, after aggregating the large-scale group dominance degree, the consensus index is calculated to identify any inconsistent sub-clusters. Feedback adjustments are made based on trust relationships until a consensus is reached. The TODIM method is then applied to calculate the corresponding ranking results. Finally, an illustrative example is applied to show the feasibility of the proposed model.

The proposed method is practical and effective which is verified by the real case study. By taking into account the trust relationships among DMs in the core process of LSGDM, it indeed has an impact on the decision outcomes. We also specifically address this issue in Chapter Five. The proposed method fully incorporates the bounded rationality of DMs, namely their tendency to accept the opinions of trusted experts, which aligns more with their psychology. The two-stage consensus model proposed in this paper effectively addresses the limitations of traditional assessment-based methods.

This study establishes a two-stage consensus model based on trust relationships among DMs, which can assist DMs in better understanding trust issues in complex decision-making, enhancing the accuracy and efficiency of decisions, and providing more scientific decision support for organizations such as businesses and governments.

This paper aims to promote the higher quality development of high-tech enterprises in China. While science and technology have greatly promoted human civilization, resources have been excessively consumed and the environment has been sharply polluted. Therefore, it is particularly important for current enterprises to make use of scientific and technological innovation to maximize the benefits of mankind, minimize the loss of nature, and promote the sustainable development of our country.

By using DEA-Banker-Charnes-Cooper (BCC) model and DEA-Malmquist model, this paper comprehensively examines the innovation efficiency of high-tech enterprises from both static and dynamic perspectives, and conducts a provincial comparative study with the panel data of ten representative provinces from 2011 to 2020.

The research findings are as follows: the rapid number increase of high-tech enterprises in most provinces (cities) is accompanied by an ineffective input–output efficiency; the quality of high-tech enterprises needs to comprehensively examine both input–output efficiency and total factor productivity; and there is not a positive correlation between element investment and innovation performance.

Because the DEA model used in this paper assumes that the improvement direction of invalid units is to ensure that the input ratio of various production factors remains unchanged but sometimes the proportion of scientific and technological activities personnel and the total research and development investment is not constant. In the future, the nonradial DEA model can be considered for further research. Due to historical data statistics, more provinces, cities and longer panel data are difficult to obtain. The samples studied in this paper mainly refer to the provinces and cities that ranked first in the number of national high-tech enterprises in 2020. Limited by the number of samples, DEA analysis failed to select more input and output indicators. In the future, with the accumulation of statistical data, the existing efficiency analysis will be further optimized.

Aiming at the misunderstanding of emphasizing quantity and neglecting quality in the cultivation of high-tech enterprises, this paper comprehensively uses DEA-BCC model and DEA Malmquist index decomposition method to make a comprehensive comparative study on the development of high-tech enterprises in ten representative provinces (cities) from two aspects of static efficiency evaluation and dynamic efficiency evaluation.

Stakeholders in complex capital projects are characterized by complicated interactions, adversarial short-term relationships and cooperative demand for deliverables. Unhealthy interfaces between stakeholders often lead to significant interface conflicts, which gradually become apparent in the construction stage. However, stakeholder interface health (SIH) has not been well understood and measured in the construction industry by either scholars or practitioners. It is essential to identify unhealthy interface relationships between stakeholders by comprehensively assessing SIH for enhancing project performance.

The study provided a comprehensive framework to assess SIH. The assessment was based on Wuli-Shili-Renli theory. Moreover, the CRITIC and Grey-TOPSIS methodologies were applied to precisely evaluate the SIH level. Besides, graph-based interface networks were developed to visualize SIH. At last, the framework was applied to a mass rapid transit project in China to test the validity of the study.

The result showed that stakeholder interfaces with strict contract constraints are healthier. On the other hand, IM behaviors make up for the soft coordination mechanism without contract constraints to a certain extent. The results of the case study were consistent with the actual project practices. The proposed framework provided a useful IM tool for assessing and visualizing SIH.

The limitation of this study is that only the mass rapid transit project was selected for empirical analysis to validate the effectiveness of the proposed framework. It is recommended that the proposed framework be applied to other types of complex capital projects to further discussions in IM.

Theoretically, this study introduces a comprehensive framework to measure the health of stakeholder interfaces in complex capital projects, which helps to provide a theoretical basis and methodological support for stakeholder interface management.

Practically, applying SIH assessment to existing interface management procedures can help the project manager identify interface conflicts between stakeholders in time and eventually contribute to the improvement of PM performance. At the same time, the interface management team tracks the responsibilities of unhealthy interface stakeholders and requires them to take measures to improve the SIH level. Stakeholder interfaces with lower health scores should be given more attention. The proposed framework can serve as a novel IM approach to identify weaknesses in IM and take targeted management measures to alleviate unhealthy stakeholder interface relationships.

The study provides an innovative method for scientifically and accurately assessing SIH. This research can help scholars and practitioners in the project management field facilitate the diagnosis of unhealthy interface relationships and provide decision support for the project management theoretical foundation.