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Kefir is a probiotic grown with milk, with a slightly sour flavor and has been consumed for thousands of years. Kefir grains contain bacteria and yeast. In the past, kefir was administrated as a drug against tuberculosis, cancer and gastrointestinal disorders. The purpose of this paper is to investigate the potential anticancer properties of kefir and its ability to affect natural killer cells' (NKCs') activity.

The assay of cytotoxic activity of NKCs by cytometric analysis was used, which included four stages: isolation of natural killers; quantification of target cells; incubation of natural killers with target cells at ratios of 12.5:1, 25:1 and 50:1 in CO2 incubator; and measurement of cells with flow cytometer. The same procedures were repeated, but the third stage was modified with the addition and incubation of 50, 75, and 100 μL kefir (of 24 hour culture with 3.5 per cent fresh milk) with K562 and leiomyosarcoma cells lines, and kefir and NK cells with K562 or LMS cell lines.

The results showed that kefir's cytotoxic activity without the presence of NKCs reached an average of 85 per cent in both cell lines. With the addition of NK cells in kefir, the cytotoxic activity further increased by 10 per cent. Kefir alone did not cause any statistically significant death in NK cells. Kefir seems to have significant cytotoxic action by itself without stimulating NK cells in a significant manner. However, further studies are needed to establish the role of kefir in the prevention and treatment of neoplasmatic diseases.

The paper provides information and new data, for nutritionists and clinical dietitians, about the effects of kefir in the prevention of cancer.

A lesson has been learned from the pandemic experience that less damages to the environment and realizing more social responsibilities would be the direction of the post-pandemic period globally. The purpose of this study is to focus on identifying the appropriate determinants of the proposed urban travel behavior model to develop Smart Mobility in Smart Cities to protect the environment. Potential to realize Smart Cities with infrastructure development has been explored in this study if road users are keen to combat climatic change which is clear from the challenges of flattening the infection rate through the enforcement of rules and regulations by the various government.

The proposed urban travel behavior model includes sub-drivers for each of the main drivers in the theory of interpersonal behavior (TIB). These sub-drivers emphasize in forming intentions to perform the behavioral changes while driving on urban roads during COVID-19 and post-pandemic periods. A primary online survey was conducted among road commuters in the most crowded place in Malaysia, the Greater Kuala Lumpur. A total of 383 respondents who frequently drive on road during the past one year were surveyed for this study. This data analysis of this quantitative study applied a partial least squares-structural equation modeling approach to determine the significant findings and results.

The significant findings of the study reveal that environmental consciousness and timely deviation in driving during traffic congestion are positively and significantly influencing the travel behavior performance (TBP) of commuters on urban roads. On the other hand, wet conditions due to weather, narrow road infrastructure and habits of road commuters are negatively influencing TBP. Social responsibility is positively and significantly influencing TBP through the mediating effect of the intention of road commuters’ behavior.

The current environmental concerns and societal adherence efforts in breaking the chain of the infectious COVID-19 among people can be manifested to develop Smart Cities with less air and noise pollution in the future. In this context, the present study proposes an urban travel behavior model and tests for its suitability of a greener and cleaner environment for the benefit of future generations. The limitation of the present study is that travel hazards are not included in the framework, as it is a topic of its own volume.

It is timely to implement Smart Mobility on road business models for Smart Cities as the consequences of the pandemic make us to realize the importance of environmental concerns and the social responsibilities of everyone. TIB considers four drivers, namely, attitude, subjective norm, affect and habit which induce intention to perform behavioral decisions. The novelty of the present study is the development of sub-drivers for these four drivers in the context of the urban travel behavior model.

The purpose of this paper is to investigate the influence of driver demographic characteristics on the driving safety involving cell phone usages.

A total of 1,432 crashes and 19,714 baselines were collected for the Strategic Highway Research Program 2 naturalistic driving research. The authors used a case-control approach to estimate the prevalence and the population attributable risk percentage. The mixed logistic regression model is used to evaluate the correlation between different driver demographic characteristics (age, driving experience or their combination) and the crash risk regarding cell phone engagements, as well as the correlation among the likelihood of the cell phone engagement during the driving, multiple driver demographic characteristics (gender, age and driving experience) and environment conditions.

Senior drivers face an extremely high crash risk when distracted by cell phone during driving, but they are not involved in crashes at a large scale. On the contrary, cell phone usages account for a far larger percentage of total crashes for young drivers. Similarly, experienced drivers and experienced-middle-aged drivers seem less likely to be impacted by the cell phone while driving, and cell phone engagements are attributed to a lower percentage of total crashes for them. Furthermore, experienced, senior or male drivers are less likely to engage in cell phone-related secondary tasks while driving.

The results provide support to guide countermeasures and vehicle design.