Search results

In this study, the authors aimed to explore consumer perspectives on accelerated access to medicines. The authors were particularly interested in how they balance competing considerations of safety, efficacy, equity and access; whether and how their views change when there are different levels of uncertainty surrounding the safety and efficacy of new medicines; and the procedures that they think should be used to make decisions about accelerated access to new medicines.

This was an exploratory qualitative study. Thirteen semi-structured interviews with patient advocates and two focus groups with patients were conducted and analysed thematically. Interviews and focus groups were audio recorded and transcribed verbatim. Data were analysed through inductive thematic analysis.

Participants outlined a range of justifications for accelerated access, including addressing unmet medical needs and encouraging further research and development. However, they were also cognisant of the potential risks and viewed ongoing data collection, disinvestment and market withdrawal as ways to address these. They also emphasised the importance of transparent decisions being made by people with relevant expertise, based on a thorough consideration of scientific evidence and stakeholder perspectives.

This is the first study to comprehensively explore Australian consumers' views of accelerated access to medicines. The results suggest that consumers want timely access to new medicines, but not at the expense of safety, efficacy, equity and sustainability. While accelerated access programs are likely to be welcomed by consumers, they must be fully informed of their conditions and limitations, and robust post-market data surveillance must be implemented and enforced to protect the interests of both individual patients and the broader community.

This study aims to examine a large, non-disclosed production contract awarded to Lockheed Corp. in the context of a trade-off between a contractually required non-disclosure clause and the need (as a publicly traded firm) to disclose material information to its shareholders. This production contract generated significant cash flows to the firm as evidenced by growth in its earnings. However, the existence of the production contract and its contribution to Lockheed’s earnings, was not disclosed by the firm to shareholders and potential investors while the production contract was being executed.

The authors examine the market reaction to several key contract events which were not disclosed at the time they occurred, in compliance with the contractually required non-disclosure clause.

A statistically significant stock price reaction around the time of the award of this non-public contract, indicative of trading by some capital market participants using non-public information was documented.

Because similar large non-public contracts funded by the government are common in the industrial economy, we conclude by discussing implications for organizational structure, firm’s cost of capital, equity-based compensation and market efficiency.

The aim of this paper is to demonstrate how an imaginative sourcing policy can be used to provide a competitive advantage for clothing manufacturers based in high‐cost countries. The paper shows how Chorus Line Corporation implemented their sourcing mix, through a combination of production in different regions, to maintain and develop their competitive position in the womenswear market in the USA. The company's basic data and decisions are outlined as an example of how one privately owned company views the sourcing and production decision. In this way the paper will help firms to develop their own global production strategies with balanced sources to meet their business and market strategies.

The purpose of this research-based philosophical piece is to present a progressive manifesto for public libraries in the 21st century to address gaps in embracing diversity in its holistic dimensions and representing such information in their strategic planning and web documentations.

Content analysis of public library websites in the USA informed the development of a Strategic Diversity Manifesto that includes the “who”, the “what” and the “how” components to describe and discuss diversity-related matters in their strategic planning and web representations.

The Strategic Diversity Manifesto provides a mechanism for individual public library agencies, in their localized context and environment, to strategically inquire, describe, discuss, reflect, analyze and translate into concretized actions their picture of diversity as grounded in the reality of their representative communities.

The Strategic Diversity Manifesto presents a more a comprehensive and consolidated picture of diversity beyond isolated strategies seen in past efforts. It is a broader level of analysis and “picture painting” of the agency’s context, which may not be as detailed as compared to other modes of description, though as a result, it is more holistic instead of fragmentary. The aim is first and foremost to provide a basis for reflective thought and discussion.

This paper summarizes and compares the perspectives of the prior essays in this issue. Goes on to argue that education for democracy requires dialogical, authentic learning rather than the commodification of uniform, standardized knowledge and its acquisition touted by those marketizing education primarily for economic purposes. The paper calls upon educators and university scholars to resist the identification of learning with text scores, and to defend the traditional role of learning in the human emancipation of citizens whose knowledge and life lessons learned in school contribute to their wise governance of themselves.

To identify controls that can harness the power and capabilities of instant messengers (IM) while minimizing potential security risks.

A risk analysis method and (CIS)² model are used.

IM is a great tool for enterprise productivity. However, it has so many risks, but one could identify and control these risks with technical and managerial countermeasures.

This paper fails to provide detailed and specific risks of commercial IMs, and the case study provided in this paper focuses on the technical rather than managerial issues.

A very helpful case study which provides general risks and controls of recent IMs for the security officers of various organizations.

This paper outlined the risks of IM and potential controls for securing public IM in the workplace.

This paper reports an empirical study conducted in British organisations focussing on the role of investor relations as part of a co‐ordinated marketing communications strategy. Consequently this study considers the greatly neglected research area of the management of relationships between national and international organisations and both investors and those others who might consider themselves significant financial stakeholders. It examines the organisational role of investor relations within a co‐ordinated communication programme and suggests that communication with financial stakeholders has a significant role to play as part of a developed corporate communication strategy.

To provide the strategic model of approach which helps enterprise executives to solve the managerial problems of planning, implementation and operation about information security in business convergence environments.

A risk analysis method and baseline controls of BS7799 were used to generate security patterns of business convergence. With the analysis of existing enterprise architecture (EA) methods, the framework of the enterprise security architecture was designed.

The adaptive framework, including the security patterns with quantitative factors, enterprise security architecture with 18 dimensions, and reference models in business convergence environments, is provided.

Information assets and baseline controls should be subdivided to provide more detailed risk factors and weight factors of each business convergence strategy. Case studies should be performed continuously to consolidate contents of best practices.

With the enterprise security architecture provided in this paper, an enterprise that tries to create a value‐added business model using convergence model can adapt itself to mitigate security risks and reduce potential losses.

This paper outlined the business risks in convergence environments with risk analysis and baseline controls. It is aguably the first attempt to adapt the EA approach for enterprise executives to solve the security problems of business convergence.

The first purpose of the present study is to investigate the coverage of journal articles in Physics in various sources of altmetrics. Secondly, the study investigates the relationship between altmetrics and citations. Finally, the study also investigates whether the relationship between citations and altmetrics was stronger or weaker for those articles that had been mentioned at least once in the sources of altmetrics.

The journal articles in Physics having at least one author from an Indian Institution and published during 2014–2018 in sources of altmetrics have been investigated. Altmetric.com was used for collecting altmetrics data. Spearman’s rank correlation coefficient (ρ) has been used as the data found to be skewed.

The highest coverage was found on Twitter (22.68%), followed by Facebook (3.62%) and blogs (2.18%). The coverage in the rest of the sources was less than 1%. The average Twitter mentions for journal articles tweeted at least once was found to be 4 (3.99) and for Facebook mentions, it was found to be 1.48. Correlations between Twitter mentions–citations and Facebook mentions–citation were found to be statistically significant but low to weak positive.

The study concludes that due to the low coverage of journal articles, altmetrics should be used cautiously for research evaluation keeping in mind the disciplinary differences. The study also suggests that altmetrics can function as complementary to citation-based metrics.

The study is one of the first large scale altmetrics studies dealing with research in Physics. Also, Indian research has not been attended to in the altmetrics literature and the present study shall fill that void.

During the 1980s' Decade of the Disabled, legislation, advocacy activities, and special programs stimulated increased awareness of the rights of people with disabilities for better access to education, employment, housing, and information. In response to the growing need for easier access to information found in a public library, staff at the Phoenix Public Library designed a library Special Needs Center to make the services and resources of the library totally accessible. The following policy and mission statements illustrate this effort.