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Minority stress theory suggests enhanced HIV risk for those experiencing social marginalization, while an intersectionality framework posits that forms of marginalization may interact. The purpose of this paper is to understand how race/ethnicity- and gender-based discrimination may impact HIV risk among transgender or transsexual (trans) people.

The Trans PULSE project – a community-based research study in Ontario, Canada – used respondent-driven sampling to survey 433 trans participants, including 35 Aboriginal persons and 62 non-Aboriginal persons of colour. Descriptive and regression analyses were weighted to adjust for recruitment probabilities.

Most Aboriginal persons (65 per cent, 95 per cent CI: 37-90) and persons of colour (90 per cent, 95 per cent CI: 74-100) reported at least one experience of racism or ethnicity-based discrimination, and the vast majority had experienced transphobia (90 and 92 per cent, respectively). Among non-Aboriginal trans persons of colour, experiences of racism and transphobia interacted in increasing odds of engagement in high-risk sex. Increases in experience of one type of discrimination had strongest effects on HIV risk when coupled with high levels of the other.

Persons of colour were ethno-racially diverse; it is possible that different experiences of racism, with divergent effects, were collapsed. Odds ratios may overestimate actual risk ratios.

While some sub-groups of trans people of colour have been identified as highly vulnerable to HIV, few studies have explored the impact of discrimination. This paper explores the roles of two types of discrimination in engendering HIV-related risk, and suggests potential limits to resiliency in the face of high levels of discrimination targeting multiple facets of identity.

The purpose of this paper is to outline the use of intersectionality theory in research with gender and sexual minorities – that is, with lesbian, gay, bisexual, trans, and queer (LGBTQ) people, and lesser-studied groups such as two-spirited people.

First, the paper note the limited way that LGBTQ research has taken up issues of intersecting oppression. The paper outlines why theoretical and methodological attention to overlapping oppressions is important, and why theorists of intersectionality have identified the additive model as inadequate. The paper presents a sketch of current best practices for intersectional research, notes special issues for intersectional research arising within qualitative and quantitative paradigms, and finishes with an overview of how these issues are taken up in this special issue of Ethnicity and Inequalities in Health and Social Care.

Current best practices for intersectional research include. Bringing a critical political lens to data analyses; contextualizing findings in light of systemic oppressions; strategically using both additive and multivariate regression models; and bringing a conscious awareness of the limitations of current methods to our analyses.

This paper addresses the use of intersectionality theory in research with gender and sexual minorities, highlighting methodological issues associated with qualitative and quantitative paradigms in LGBTQ research.