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Among thoracic malformations, pectus deformities have the highest incidence and can result in a wide range of severe and mild clinical manifestations. Recently, the treatment of pectus deformities is shifting from traditional approaches toward customized solutions. This occurs by leveraging innovative rapid prototyping tools that allow for the design and fabrication of patient-specific treatments and medical devices. This paper aims to provide a comprehensive view of the growing literature in this area to analyze the progress made in this direction.

The search was performed on major search engines through keywords inherent to reverse engineering (RE) and additive manufacturing (AM) technologies applied to pectus deformities and related treatments, selecting 54 papers. These were analyzed according to the addressed pathology, the hardware and software tools used and/or implemented and their integration within the clinical pathway.

First, the analysis led to analyze and divide the papers according to how RE and AM technologies are applied for surgical and non-surgical treatments, pathological assessment and preoperative simulation and planning. Second, all papers were considered within the typical rapid prototyping framework consisting of the three phases of three-dimensional (3D) scanning, 3D modelling and 3D printing.

To the best of the authors’ knowledge, to date, no survey has provided a comprehensive view of innovative and personalized treatment strategies for thoracic malformations; the present work fills this gap, allowing researchers in this field to have access to the most promising findings on the treatment and evaluation of pathology.

We describe a 13 1/2‐year‐old boy with de novo inverted interstitial duplication 8q22.1‐q21.1 associated with mild phenotypic abnormalities, learning disabilities and autism. Psychometric and psychiatric evaluation was performed. Clinical genetic evaluation was supported by chromosome analysis of blood lymphocytes using GTG‐banding technique and Fluorescent In Situ Hybridization (FISH) with whole chromosome painting 8 probe. Clinical evaluation revealed mild phenotypic abnormalities, moderate learning disabilities and mild autistic disorder. The karyotype of the proband was interpreted as 46, XYqh+pat, 8q+.ish inv dup(8)(q22.1;q21.2)(wcp8+) de novo. Although partial trisomy for other segments of 8q, as well as mosaic trisomy 8, have been described in numerous cases, interstitial duplication of 8q21‐q22 seems extremely rare and the severity of the phenotypic abnormalities ranges from mild to profound.

This study investigates how virtual reality (VR) travel attributes (e.g. sense and quality of information) influence spectators' flow experience, how emotion and past experience affect enjoyment and examines the impact of flow experience and enjoyment on satisfaction and booking or visiting intention.

The VR tour stimuli were fabricated using scenic views from the National Aquarium in the USA. Participants were equipped with Matterport VR and audio headsets and started their virtual travel. Once the participants completed their VR tours, they were asked to complete the questionnaire. Using the stimulus-organism-response theory, 303 valid responses were analyzed using partial least square structural equation modeling (PLS-SEM).

The results showed that the sense and quality of information in VR travel positively and significantly impacted the flow experience. Moreover, emotions and past experiences positively and significantly influenced the enjoyment of VR travel. Similarly, flow experience and enjoyment positively and significantly affect satisfaction. However, satisfaction with VR-related tourism experiences negatively affects users' bookings and visiting intentions.

This study concludes that, from Thai tourists' perspectives, virtual travel should be used as a solution only during the pandemic because, in the long term it can cause a loss to the business chain in the tourism industry.

To the best of the authors' knowledge, no prior research has examined the influence of past experiences and emotions on satisfaction with VR travel.