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This paper aims to study the impact of combination Lactobacillus Rhamnosus Heriz I and Beta glucan on quality of life (QOL) in breast cancer (BC) patients receiving chemotherapy.

In all, 30 women with BC were enrolled in this randomized double-blind placebo-controlled clinical trial. Intervention group received either daily one capsule of L. rhamnosus strain Heriz I (2 × 10⁷ CFU) and two 10-mg capsules of soluble1–3,1–6,D-beta glucan and the placebo group receiving placebo, interval between two courses of chemotherapy. Health-related QOL was evaluated at baseline and end of the trial using the EORTC QOL Questionnaire version.3.0 (EORTC QLQ-C30).

The results showed that combination of L. rhamnosus Heriz I and Beta glucan supplementation in BC patients during chemotherapy improved functional scales score from 37.3 ± 12.1 to 39.8 ± 6.8 and this increase in comparison with placebo was significant after adjusting baseline value (p = 0.015). Changes in symptoms scores were not significant after intervention (p = 0.05) but the decreased score (66.1 ± 12.9 to 60.6 ± 9.4) was considerable clinically. As well as, changes in global health status/QOL score in intervention group in comparison with the placebo group was not significant (p = 0.93).

The findings suggest that combination of L. rhamnosus Heriz I and Beta glucan may be associated for improving functional scales and symptoms in patients with BC who underwent chemotherapy. To prove positive effect of supplements on other aspects of QOL, further studies are needed.

This research aims to test the simultaneous effects of the perceived threat of COVID-19, e-health literacy, e-health access barrier, loyalty toward healthy foods in general, loyalty toward functional foods, the affordability of healthy foods in general and the affordability of functional foods on health-related quality of life (HrQoL) during the COVID-19 pandemic.

A survey with 400 respondents in Banten, Indonesia, was performed. The data were analyzed using multiple regression analysis.

The results of the research showed that HrQoL during the COVID-19 pandemic was positively affected by e-health literacy and the affordability of healthy foods in general while negatively affected by the e-health access barrier, the perceived threat of COVID-19 and loyalty toward healthy foods in general. Furthermore, HrQoL was not influenced by loyalty toward and affordability of functional foods.

This research was conducted in Banten. Due to the operational limitations during the COVID-19 pandemic, this research used a purposive sampling technique. Therefore, the next research should retest the model in different contexts and locations.

To improve HrQoL during the COVID-19 pandemic, citizens need to be educated on finding and utilizing credible online health information during the COVID-19 pandemic. Governments and health service providers should also strive to offer ease of access to credible online health information. Furthermore, the affordability of healthy foods, in general, should be managed well.

A few studies on HrQoL during COVID-19 pandemic were performed. However, there is a lack of paper that examines the role of food customer loyalty and affordability in a model of HrQoL during the COVID-19 pandemic. To the best of the authors’ knowledge, this paper is the first that involved and tested the role of food customer loyalty and affordability in a model of HrQoL during the COVID-19 pandemic.

This paper aims to investigate the potential relationship between depression, diabetes knowledge and self-care management with quality of life in diabetic patients.

This analytical cross-sectional study was conducted on 309 diabetic patients in Tabriz, Iran in 2015-2017. Quality of life was assessed by a validated questionnaire. The Persian version of the Beck Aeron questionnaire was used to assess the depression status. Knowledge and self-care management was evaluated by the health belief model questionnaire. Simple and multiple regression models were used to determine the relationship between the mentioned factors and the quality of life in diabetic patients.

Thirty-six per cent of the patients suffered from depression. The mean score of the total quality of life was 33.75 ± 8.72. The scores of the three domains of the quality of life were less than the normal range (“complication of diabetes” domain: 9.93 ± 3.16, “diagnosis, therapy and follow-up” domain: 10.91 ± 3.31, “psycho-social effect of diabetes” domain: 12.93 ± 4.41). The score of “complication of diabetes” score in males was significantly higher than females (p = 0.001). There was a significant relationship between depression (p < 0.001), self-care management (p = 0.019) and two parameters of knowledge (diet: p = 0.006 and diabetes: p = 0.004) with quality of life of diabetic patients.

The obtained results presented an unfavorable status of knowledge, physical and mental health in diabetic patients and a strong relationship between health-related factors with quality of life. Therefore, it is suggested to hold community-based health-promoting programs to enhance the overall life satisfaction in people with diabetes.