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Digital microfluidic devices have been demonstrated to have great potential for a wide range of applications. These devices need expensive photolithography process and clean room facilities, while printed circuit board (PCB) technology provides high configurability and at low cost. This study aims to investigate the mechanism of electrowetting-on-a-dielectric (EWOD) on PCB by solving the multiphysics interaction between fluid droplet and electric field. The performance of system will be improved by inducing an efficient electric field inside the droplet.

To induce an electric field inside the droplet on a PCB and change the initial contact angle, the mechanism of EWOD is studied based on energy minimization method and a set of simulations are carried out by considering multiphysics interaction between the fluid droplet and external electric field. The performance of EWOD on a PCB system is investigated using different electrode structures.

Surface tension plays an efficient role in smaller sizes and can be used to move and control a fluid droplet on a surface by changing the interfacial surface tension. EWOD on a PCB system is studied. and it revealed that any change in electric field affects the droplet contact angle and as a result droplet deformation and movement. The electrode pattern is an important parameter which could change the electric potential distribution inside the droplet. Array of electrodes with square, zigzag interdigitated and crescent shapes are studied to enhance the EWOD force on a PCB substrate. Based on the results, the radial shape of the crescent electrodes keeps almost the same actuated contact line, applies uniform force on the droplet periphery and prevents the droplet from large deformation. A droplet velocity of 0.6 mm/s is achieved by exciting the crescent electrodes at 315 V. Furthermore, the behavior of system is characterized for process parameters such as actuation voltage, dielectric constant of insulator layer, fluidic material properties and the resultant velocity and contact angle. The study of contact angle distribution and droplet motion revealed that it is helpful to generate EWOD mechanism on a PCB which does not need more complicated fabrication processes.

The ability to handle and manipulate the droplets is very important for chemistry on-chip analysis such as immunoassay chips. Furthermore, a PCB-based electrowetting-on-dielectric device is of high interest because it does not need cleanroom facilities and avoids additional high-cost fabrication processes. In the present research, the EWOD mechanism is studied on a PCB by using different electrode patterns.

The purpose of this study is to develop the concept of self-adapting system which would be able to control a flow on the wing-high-lift system and protect the flow against strong separation.

The self-adapting system has been developed based on computational approach. The computational studies have been conducted using the URANS solver. The experimental investigations have been conducted to verify the computational results.

The developed solution is controlled by closed-loop-control (CLC) system. As flow actuators, the main-wing trailing-edge nozzles are proposed. Based on signals received from the pressure sensors located at the flap trailing edge, the CLC algorithm changes the amount of air blown from the nozzles. The results of computational simulations confirmed good effectiveness and reliability of the developed system. These results have been partially confirmed by experimental investigations.

The presented research on an improvement of the effectiveness of high-lift systems of modern aircraft was conducted on the relatively lower level of the technology readiness. However, despite this limitation, the results of presented studies can provide a basis for developing innovative self-adaptive aerodynamic systems that potentially may be implemented in future aircrafts.

The studies on autonomous flow-separation control systems, operating in a closed feedback loop, are a great hope for significant advances in modern aeronautical engineering, also in the UAV area. The results of the presented studies can provide a basis for developing innovative self-adaptive aerodynamic systems at a higher level of technological readiness.

The presented approach is especially original and valuable in relation to the innovative concept of high-lift system supported by air-jets blown form the main-wing-trailing-edge nozzles; the effective and reliable flow sensors are the pressure sensors located at the flap trailing edge, and the effective and robust algorithm controlling the self-adapting aerodynamic system – original especially in respect to a strategy of deactivation of flow actuators.

The purpose of this paper is to simulate the behaviour of the symmetrical turn‐up vortex amplifier (STuVA) to obtain insight into its maximum through‐flow operation within the eight‐port STuVA, and understand the relation between its design parameters and flow characteristics. Furthermore, it is to test the performance of different turbulent models and near‐wall models using the same grid, the same numerical methods and the same computational fluid dynamics code under multiple impingement conditions.

Three turbulence models, the standard k‐ε, the renormalization group (RNG) k‐ε model and the Reynolds stress model (RSM), and three near‐wall models have been used to simulate the confined incompressible turbulent flow in an eight‐port STuVA using unstructured meshes. The STuVA is a special symmetrical design of turn‐up vortex amplifier, and the simulation focused on its extreme operation in the maximum flow state with no swirling. The predictions were compared with basic pressure‐drop flow rate measurements made using air at ambient conditions. The effect of different combinations of turbulence and near‐wall models was evaluated.

The RSM gave predictions slightly closer to the experimental data than the other models, although the RNG k‐ε model predicted nearly as accurately as the RSM. They both improved errors by about 3 per cent compared to the standard k‐ε model but took a long time for convergence. The modelling of complex flows depends not only on the turbulence model but also on the near‐wall treatments and computational economy. In this study a good combination was the RSM, the two layer wall model and the higher order discretization scheme, which improved accuracy by more than 10 per cent compared to the standard k‐ε model, the standard wall function and first order upwind.

The results of this paper are valid for the global pressure drop flow rate. It should be desirable to compare some local information with the experiment.

This paper provides insight into the maximum through‐flow operation within the eight‐port STuVA to understand the relation between its design parameters and flow characteristics and study the performance of turbulence and near wall models.

A pneumatic‐fluidic system has been designed and built, with the purpose to recognize the side orientation of pieces.

Recently, powerful instruments for biomedical engineering research studies, including disease modeling, drug designing and nano-drug delivering, have been extremely investigated by researchers. Particularly, investigation in various microfluidics techniques and novel biomedical approaches for microfluidic-based substrate have progressed in recent years, and therefore, various cell culture platforms have been manufactured for these types of approaches. These microinstruments, known as tissue chip platforms, mimic in vivo living tissue and exhibit more physiologically similar vitro models of human tissues. Using lab-on-a-chip technologies in vitro cell culturing quickly caused in optimized systems of tissues compared to static culture. These chipsets prepare cell culture media to mimic physiological reactions and behaviors.

The authors used the application of lab chip instruments as a versatile tool for point of health-care (PHC) applications, and the authors applied a current progress in various platforms toward biochip DNA sensors as an alternative to the general bio electrochemical sensors. Basically, optical sensing is related to the intercalation between glass surfaces containing biomolecules with fluorescence and, subsequently, its reflected light that arises from the characteristics of the chemical agents. Recently, various techniques using optical fiber have progressed significantly, and researchers apply highlighted remarks and future perspectives of these kinds of platforms for PHC applications.

The authors assembled several microfluidic chips through cell culture and immune-fluorescent, as well as using microscopy measurement and image analysis for RNA sequencing. By this work, several chip assemblies were fabricated, and the application of the fluidic routing mechanism enables us to provide chip-to-chip communication with a variety of tissue-on-a-chip. By lab-on-a-chip techniques, the authors exhibited that coating the cell membrane via poly-dopamine and collagen was the best cell membrane coating due to the monolayer growth and differentiation of the cell types during the differentiation period. The authors found the artificial membrane, through coating with Collagen-A, has improved the growth of mouse podocytes cells-5 compared with the fibronectin-coated membrane.

The authors could distinguish the differences across the patient cohort when they used a collagen-coated microfluidic chip. For instance, von Willebrand factor, a blood glycoprotein that promotes hemostasis, can be identified and measured through these type-coated microfluidic chips.

A fully automatic low and high level fluidic control system for monitoring the levels of all kinds of fluids has been developed by the Air Power Division of Hunts Engineering of the Nuffield Estate, Poole, Dorset.

This paper aims presents topology optimization of microfluidic channels with reverse flow.

A circular chamber with an inlet and an outlet are chosen as an initial design domain. The energy dissipation is chosen as an objective function. The incompressible Navier–Stokes equation is applied for simulating the fluidic motion in channels. An artificial friction force which is proportional to the flow velocity is substituted into the Navier–Stokes equation for controlling the design variable.

The effect of a bifurcation angle between the inlet and the outlet on a topological structure is analyzed. The flow velocity, pressure and design variable for every bifurcation angle are obtained.

This work is instructive to the design of a microfluidic system.

The purpose of this paper is to analyze numerically forced convective conjugate heat transfer characteristics for laminar flow through a wavy minichannel.

The mass and momentum conservation equations for the flow of water in the fluidic domain and the coupled energy conservation equations in both the fluid and solid domain are solved numerically using the finite element method. The exteriors of both the walls are subjected to a uniform heat flux.

The results reveal that the theoretical model without consideration of the effect of wall thickness always predicts a lower value of average Nusselt number ( Nu¯) as compared to the case of conjugate analysis, although it varies with the thickness as well as material of the wall. For the low amplitude of the wall (α = 0.2), the performance factor (PF) becomes very high for Re in the regime of 5 (⩽) Re (⩽) 15. For any geometrical configurations, conjugate heat transfer analysis predicts higher PF as compared to that of nonconjugate analysis.

The present study finds relevance in several applications, such as solar collectors and heat exchangers used in chemical industries and heating-ventilation and air-conditioning, etc.

To the best of the authors’ knowledge, the analysis of combined influences of the thickness and the material of the wall of the channel together with the geometrical parameters of the channel, namely, amplitude and wavelength on the heat transfer and fluid flow characteristics for flow through wavy minichannel in the laminar regime is reported first time in the literature.