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1 – 1 of 1Elaine A.A. Sanibal, Nágila R.T. Damasceno, Magnus A. Gidlund and Elizabeth A.F.S. Torres
This paper aims to evaluate the association between the α‐tocopherol with the levels of serum anti‐oxLDL autoantibodies and the risk markers for cardiovascular disease.
Abstract
Purpose
This paper aims to evaluate the association between the α‐tocopherol with the levels of serum anti‐oxLDL autoantibodies and the risk markers for cardiovascular disease.
Design/methodology/approach
A normolipidemic control group (n=30) and a hypercholesterolemic group (n=33) were used. Plasma lipid profile (colorimetric method), anti‐oxLDL autoantibodies (ELISA) and α‐tocopherol (HPLC) were analysed.
Findings
The α‐tocopherol (β=−0.714; p=0.001) is negatively associated with anti‐oxLDL autoantibodies in serum and with other risk markers for cardiovascular disease (BMI, WC, total cholesterol, LDL‐c) and positively associated with HDL‐c.
Originality/value
Oxidized low density lipoprotein (oxLDL) and their autoantibodies are increased in subjects with hypercholesterolemia. The α‐tocopherol can influence the levels of serum anti‐oxLDL autoantibodies.
Details