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This paper aims to give further insights into Alzheimer's disease (AD), a devastating neurodegenerative disorder which accounts for 60‐80 per cent of late‐onset dementia. AD is genetically complex where three genes are known to cause the early‐onset familial form of disease and ten genes have been identified to contribute to the risk of developing late‐onset sporadic AD.

The paper discusses the recently identified AD susceptibility loci and outlines the various hypotheses of how these loci and the pathways in which they function may elucidate the aetiology and pathogenesis of sporadic late‐onset AD.

The loci identified to increase susceptibility to sporadic AD are not random, but instead point to defects in specific biological processes and pathways that contribute to the development of the disease. These include impairments in: innate/adaptive immunity, specifically inflammation and the complement system; endocytosis/intracellualar trafficking, which includes the internalisation of material from the cell surface and the mechanisms by which molecules are transported; and lipid processing. High levels of lipids such as cholesterol have been associated with development of AD in later life.

The paper highlights that determining the function of the known susceptibility loci, and establishing how they increase risk for AD will aid in the development of new treatments.

This paper aims to understand the opportunities and challenges to engage emerging adult gamers (aged 18–25) in adopting healthier diet behaviours through online games and related platforms such as esports and streaming. The study uses a socio-ecological approach to understand influences and suggests approaches to changing behaviours.

Purposive and convenience sampling were used to identify (n = 13) online gaming industry professionals and emerging adult (EA) gamers for interview. Qualitative thematic analysis of data using NVivo was undertaken.

Bi-directional influences were found that are potentially impacting EA diet behaviours. Food industry advertising and sponsorships were identified as dominant influences within the behavioural ecology, using microcelebrities and esports events to target EAs. The study identifies a need for social marketers to engage EA gamers in healthful behaviours through interventions across various levels of the behavioural ecology, including those upstream with industry and potential government regulation, to promote better health and balance food marketing. It also identifies future research avenues for engaging gamers in good health.

To the best of the authors’ knowledge, this is the first study to explore the impact of the gaming behavioural ecology on EA diet behaviour. It identifies new channels that social marketers can use to engage EAs, who are difficult to reach through more traditional marketing channels.