Alternative Healthy Eating Index (AHEI)-2010, an index that determines the quality of a diet, was created to predict the risk of chronic diseases. Nevertheless, it is unclear whether this index can predict the risk of prostate cancer, one of the most prevalent cancers among men around the world. The study aims to investigate the association between adherence to the AHEI-2010 and the risk of prostate cancer in Iranian men.
The case–control study was conducted in Kermanshah, Iran in the year 2016. The study included 50 cases of Iranian men with prostate cancer and 150 healthy controls. Anthropometric indices were measured by bioelectric impedance analysis (BIA). The AHEI-2010 included 11 food components that were assessed by using a 147-item food frequency questionnaire. A multivariate logistic regression was performed to analyze the association of the AHEI-2010 (expressed as a dichotomous variable) with prostate cancer.
As per the analysis, there were no significant differences in age, body mass index (BMI) and waist-to-hip ratio (WHR) between case and control groups, statistically. After adjustment for potential confounders, the higher AHEI-2010 scores were associated with a lower risk of prostate cancer (OR AHEI > 55 vs ≤ 55 = 0.26; 95% CI: 0.11-0.63). Moreover, the Mean of AHEI scores was higher in controls than in the cases (p < 0.001).
The authors’ findings suggest that adherence to the dietary patterns with high scores of AHEI-2010 is associated with a reduced risk of prostate cancer, so this index may be used as an effective measure to predict prostate cancer.
Bagheri, A., Nachvak, S.M., Abdollahzad, H. and Mohammadi, F. (2019), "Does alternative healthy eating index can predict the risk of prostate cancer?", Nutrition & Food Science, Vol. 50 No. 1, pp. 96-104. https://doi.org/10.1108/NFS-01-2019-0024
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