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Times of crisis and new entrepreneurial opportunities in highly regulated environments: the case of mRNA-biotechs during COVID-19 pandemic

Yann Truong (Department of Strategy, ESSCA School of Management, Lyon, France)
Yosr Ben Tahar (Paris School of Business, Paris, France)

International Journal of Entrepreneurial Behavior & Research

ISSN: 1355-2554

Article publication date: 1 November 2023

Issue publication date: 24 September 2024

98

Abstract

Purpose

Crises, such as COVID-19 pandemic, are critical events that provoke important changes in organizational practices, regulations and actors' roles. The pharmaceutical sector has been strongly affected because of the urgency to produce drugs that are effective and safe. However, the validation process and regulations are historically restrictive in this sector. This study aims to study how biotechnology firms, small companies lacking resources, have undertaken strategic actions during crisis time to induce important changes to their advantage within such a highly regulated environment.

Design/methodology/approach

Interviews were conducted with 21 managers in four mRNA-based biotechnology firms.

Findings

Results showed that rhetorical strategies and institutional actions are used in order to manage change opportunities. Media attention, greater openness of state agencies and public willingness to accept new ways of treatment illustrated this opportunity of change in favor of biotechnology firms.

Originality/value

Highly regulated environments tend to be unfavorable to smaller firms with limited resources to overcome these constraints. The authors show that times of crisis can reverse this assumption through the provision of new opportunities as long as the smaller firms skillfully use strategic actions to exploit the institutional changes at play.

Keywords

Citation

Truong, Y. and Tahar, Y.B. (2024), "Times of crisis and new entrepreneurial opportunities in highly regulated environments: the case of mRNA-biotechs during COVID-19 pandemic", International Journal of Entrepreneurial Behavior & Research, Vol. 30 No. 8, pp. 2158-2174. https://doi.org/10.1108/IJEBR-02-2023-0196

Publisher

:

Emerald Publishing Limited

Copyright © 2023, Emerald Publishing Limited

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