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Synthesizing a nanoparticle distribution in magnetic fluid hyperthermia

P. Di Barba (Department of Electrical Engineering, University of Pavia, Pavia, Italy)
F. Dughiero (Department of Electrical Engineering, University of Padova, Padova, Italy)
E. Sieni (Department of Electrical Engineering, University of Padova, Padova, Italy)

Abstract

Purpose

The purpose of this paper is to present the synthesis of magnetic fluid characteristics, like diameter of nanoparticles (NPs) and their concentration, in order to obtain a prescribed temperature rate. An evolution strategy algorithm is used in the optimization procedure, while three‐dimensional finite‐element (FE) modelling is used for magnetic field and thermal field analysis in transient conditions.

Design/methodology/approach

FE analysis has been used in order to compute the magnetic and thermal field in a suitable model of the tumor region. The power density due to NP has been accordingly derived.

Findings

The NP distribution, giving a prescribed thermal response, is synthesized.

Practical implications

The proposed method can be used to design a therapeutic treatment based on magnetic fluid hyperthermia.

Originality/value

The paper belongs to a streamline of innovative studies on computational hyperthermia.

Keywords

Citation

Di Barba, P., Dughiero, F. and Sieni, E. (2011), "Synthesizing a nanoparticle distribution in magnetic fluid hyperthermia", COMPEL - The international journal for computation and mathematics in electrical and electronic engineering, Vol. 30 No. 5, pp. 1507-1516. https://doi.org/10.1108/03321641111152667

Publisher

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Emerald Group Publishing Limited

Copyright © 2011, Emerald Group Publishing Limited