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This chapter will describe and assess initiatives by the University of Oslo (UoO) in Norway, the purpose of which has been to expand and improve collaboration with universities in Africa, notably the University of Dar es Salaam (UDSM) in Tanzania. UoO has a long history of North-South cooperation with a wide range of institutions on the African continent. In 2009, the UoO initiated a collaborative program with UDSM entitled “Program for Institutional Transformation Research Outreach” (PITRO) III, supported by Norwegian Agency for Development Co-operation (NORAD). The chapter will situate the UoO-UDSM cooperation in relation to Norwegian aid, and compare the program with previous programs, giving attention to the ways they were developed, how problems and challenges were tackled, and the probable consequences for Tanzania’s development. The chapter will compare and contrast the structure and experiences from these programs, and will point out strengths and weaknesses. Attention will be given to the rights-based approach, an important new dimension in North-South cooperation on higher education in Africa. It will be argued that the incorporation of this approach provides a basis for developing new policies and programs that strengthen African collaboration within research, education, and capacity building in higher education.