Principles of Psychiatric Genetics

International Journal of Health Care Quality Assurance

ISSN: 0952-6862

Article publication date: 31 August 2012

280

Keywords

Citation

(2012), "Principles of Psychiatric Genetics", International Journal of Health Care Quality Assurance, Vol. 25 No. 7. https://doi.org/10.1108/ijhcqa.2012.06225gaa.011

Publisher

:

Emerald Group Publishing Limited

Copyright © 2012, Emerald Group Publishing Limited


Principles of Psychiatric Genetics

Principles of Psychiatric Genetics

Article Type: Recent publications From: International Journal of Health Care Quality Assurance, Volume 25, Issue 7

Please note that unless expressly stated, these are not reviews of titles given. They are descriptions of the books, based on information provided by the publishers

Edited by: John I. Nurnberger Jr and Wade Berrettini,Cambridge University Press,ISBN:978-0-521-89649-8,July 2012

Keywords: Psychiatric genetics strategy, Behavioural disorder management, Genome research and healthcare

Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer’s disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.

Contents include:

  • Contribution of genetic epidemiology to our understanding of psychiatric disorders.

  • A basic overview of contemporary human genetic analysis strategies.

  • In silico analysis strategies and resources for psychiatric genetics.

  • Gene expression studies in psychiatric disorders.

  • Pharmacogenetics in psychiatry.

  • Functional validation of candidate genetic susceptibility factors for major mental illnesses: from protein chemistry, cell biology, animal study, to human brain imaging.

  • Epigenetic mechanisms in drug addiction and depression.

  • Panic disorder.

  • The genetics of phobic disorders and generalized anxiety disorder.

  • Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders.

  • Post-traumatic stress disorder.

  • Antisocial behavior: gene environment interplay.

  • Learning disabilities.

  • Autism and autism spectrum disorders.

  • Genetics of major depression.

  • The genetics of anorexia and bulimia nervosa.

  • Genetics and common human obesity.

  • Alcoholism.

  • Nicotine dependence.

  • Genetics of stimulant dependence.

  • Genetics of personality disorders.

  • Ethical issues in behavioral genetics.

  • Genetics of Tourette syndrome and related disorders.

  • Endophenotypes.

  • Developmental disorders.

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