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LETS Act: a behavioral activation treatment for substance use and depression

Stacey B Daughters ( UNC Chapel Hill Chapel Hill United States )
Jessica F Magidson ( Massachusettes General Hospital/Harvard Medical School Boston United States )
Carl W. Lejuez ( University of Kansas Lawrence United States )
Yun Chen ( University of North Carolina at Chapel Hill Chapel Hill United States )

Advances in Dual Diagnosis

ISSN: 1757-0972

Article publication date: 2 July 2016




Substance use disorders (SUDs) often co-occur with major depressive disorder (MDD), yet treatments targeting this comorbidity are limited, especially in resource limited settings where individuals with SUDs often receive treatment.


Based upon principles of reinforcement and behavioral economic models of substance use, as well as the Brief Behavioral Activation Treatment for Depression (BATD; Lejuez et al., 2011), the Life Enhancement Treatment for Substance Use (LETS ACT; Daughters et al., 2008) was developed to meet the unique needs of patients with MDD-SUD comorbidity.


The current manuscript presents a summary of the theoretical foundations and key components of LETS ACT.


A specific focus on increasing dissemination via the flexible delivery dependent on patient and treatment setting characteristics is provided throughout.


Daughters, S.B., Magidson, J.F., Lejuez, C.W. and Chen, Y. (2016), "LETS Act: a behavioral activation treatment for substance use and depression", Advances in Dual Diagnosis, Vol. 9 No. 2/3.



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