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Genetics, a discipline of biology, is one of the most recent and rapidly advancing disciplines in science. This study aims to present a bibliometric analysis of the genetics research output of Iranian authors, map the intellectual structure of these studies and investigate the development path of this literature and the interrelationships among the main topics.

This study searched the Web of Science database for documentation of Iranian-published genetics research published up to 2020. Further, this study used HistCite software to profile and analyze the most cited articles and references and to draw their historiographies.

A database search revealed 21,329 documents that created the study population. The highest cited publications based on the Global Citation Score (GCS) and Local Citation Score (LCS) achieved scores of 602 and 47, respectively. The publication growth rate study demonstrated consistent expansion over time. The scientific maps based on LCS and GCS had five and four clusters, respectively. Furthermore, journal articles emerged as the predominant type of publication.

The significance of this study is in its contribution to understanding the genetics research position in Iran, informing policymakers and researchers, helping scientific collaboration and its impact on public attitudes and quality of life. The results of the present study, with benefits for various groups of communities, such as policymakers, academic groups and public society, can bridge the gap between theoretical research and practical implications.

The results of this study, by helping future advancement in health care, medical genetics and disease prevention, may have a direct and indirect positive influence on the quality of life. Furthermore, it may lead to more informed discussions on health care and biotechnology as well as influencing public attitudes and perceptions.

Ultimately, this study concludes that despite the proliferation of publications in terms of quantity and complexity, especially in areas such as disease diagnosis, prevention and treatment, there remains a need for more attention to other facets of genetics such as biology and biotechnology. Iranian publications are most related to population genetics, human genetics, molecular genetics, medical genetics, genomics, developmental genetics and evolutionary genetics out of 10 branches of genetics. This study reveals patterns in scientific outputs and authorship collaborations and plays an alternative and innovative role in revealing Iranian research trends in genetics.

The purpose of this study is to determine the funding ratio of BRICS nations in various research areas. The leading funding institutions that support research in the developing world have also been researched.

This study involves the funding acknowledgment analysis of the data retrieved from the “Clarivate Analytics' InCites database” under “22 specific research areas” to determine whether the publication was funded.

This study shows that China achieves the highest funding ratio of 88.6%, followed by Brazil (73.74%), Russia (72.93%) and South Africa (70.94%). However, India has the lowest funding ratio of 58.2%. For the subject areas, the highest funding ratio is by microbiology in Russia (86.6%), India (84.3%) and China (96.9%) and space science in Brazil (93.7%) and South Africa (94.82%). However, economics and business achieves the lowest funding ratio in Brazil (38.6%), India (20.1%) and South Africa (30.24%). Moreover, the regional funding agencies are the leading research sponsors in the BRICS nations.

This study implies increasing the funding ratio across various research areas, including arts, humanities and social sciences. The nations, particularly India, also need to gear up sponsoring the research to improve the funding ratio for scientific development, bringing overall good.

This study efforts to show the status of countries and research subjects in terms of funding ratio and reveals the prominent funders working toward scientific growth.

This conceptual article presents a schematic of rat maternal behavior and niche stress epigenetic effects as a case study that is then aligned with current evolutionary concepts, which raises new questions regarding immigrant assimilation and niche dynamics.

The necessary background material for rat maternal and niche(s) stress factors are incorporated into a recursive, test-operate-test (rTOT), information-only-transfer, schematic (Patterson, 2023), which is an extension and refinement of the test-operate-test-exit (TOTE) schematic of Miller et al. (1960).

The generated epigenetic rTOT demonstrates the fundamental evolutionary unit of the flexible organism within its niche(s). The rTOT also confirms that epigenetic processes, epigenetic inheritance and phenotype plasticity are significant conceptual tools for understanding evolution. The teleology of rat adaptations for niche fitness via maternal behavior has been demonstrated. Sterling's (2011) allostasis, or predictive homeostasis, is extended to include species-niche(s) interaction(s) that are governed by recursive information feedback loops that function via self-organized criticality (SOC) for species and niche(s). Use of a rat model for biosocial issues in humans is strengthened.

Epigenetic rTOT only covers the species side of the evolutionary unit. Niche(s) require(s) a separate rTOT schematic. The information modeled does not include the entire system producing epigenetic effects but models a substantial portion of it.

Epigenetic rTOT demonstrates the utility of phenotypic plasticity, epigenetics and epigenetic inheritance as explanations for inheritable behavior patterns. rTOT is a useful computational model for evolutionary issues. The issues involved in niche modeling using an rTOT schematic are briefly reviewed.

When the demonstrated epigenetic model of rat genetics and inherited behavior are applied to the issues of immigrant enclaves, epigenetic complications for the difficulties of assimilation into the culture within which the enclaves are embedded become apparent. However, the questions raised must be addressed with extreme care to avoid cultural imperialism. Such cultural issues must be modeled with an rTOT application that covers the materials involved. The limitations of human Learning III restrictions when attempting to model Learning IV issues are addressed. Research into the means by which abuse and trauma are maintained by epigenetic means is urgently needed.

The rTOT schematic visualizes rat maternal behavior and stress epigenetic effects that produce inheritable behavior patterns, which answers Jablonka's (2017) request for new computational modeling representations. The concept of allostasis, or predictive homeostasis, (Sterling, 2011) is extended to the niche(s) of the organism under study so that allostasis becomes a fully cybernetic concept governed by SOC for both the organism and its niche(s). This new case study confirmed evolutionary effects of epigenetics, epigenetic inheritance and phenotypic plasticity. Niche control of organism evolution is presented. Epigenetic applications for immigrant assimilation issues have been suggested and niche dynamic questions have been raised.

This study aims to investigate the consumer behavior toward telemedicine services in India during the COVID-19 pandemic onset. With lockdown restrictions and safety concerns in visiting brick-and-mortar clinics or hospitals during the pandemic, Telemedicine had emerged as a potent alternative for seeking redressal to health issues. Based on theory and focus interviews with the telemedicine users, the researchers proposed a model to understand the intent and actual usage of telemedicine in India.

The cross-sectional study undertaken used a questionnaire designed on a seven-point Likert scale and administered to respondents with the objective of identifying the determinants of intent and actual usage of telemedicine services. Simple random sampling was used to collect primary data. The data was cleaned and finally a sample of 405 responses complete in all respects was considered for analysis. The questionnaire comprised of 34 items and following the recommendation of Hair et al. (2016), which says the minimum sample size in structural equation modeling should be ten times the number of indicator variables, a sample size of 405 was deemed adequate.

The research paper finds that performance expectancy, attitude, credibility and self-efficacy positively impact the intention of consumers to use telemedicine services. As the effort expectancy or risk perception toward telemedicine increases the intent and actual usage of telemedicine decreases. The intention to use telemedicine emerged as a strong predictor of the actual usage of telemedicine. Intent to use telemedicine was explained 81.4% by its predictors of performance expectancy, effort expectancy, attitude, risk, credibility and self-efficacy, and actual usage was explained 79.9% by its predictors. This study also reports that telemedicine was found to be popular among chronic as well as episodic patients though the preference was skewed in favor of the episodic patients. One of the advantages of telemedicine is its availability round the clock, and the study found that 8 a. m. to 12 noon time slot as the most preferred slot for seeking telemedicine services.

Chang (2004) opined that telemedicine can fulfill the needs of all stakeholders: citizens, health-care consumers, medical doctors and health-care professionals, policymakers, and so on. Considering the promise telemedicine holds, this realm must be studied and leveraged to the full potential. The study found that patients were using telemedicine even for their day-to-day aliments. This indicates a growing popularity of telemedicine and as such an opportunity for telemedicine companies to leverage it. In India, pharmaceutical companies cannot give commercial advertisements for medicines, and the same can only be sold through a registered medical practitioner’s prescription. As such there is total dependency on the medical practitioner for the sale of medicines. Telemedicine companies offer services of home delivering medicines clubbed with medical consultation thus giving them forward integration in their business models. Using telemedicine the patients had control over the timings of the services offered, and as such the waiting time to get a consultation and subsequent treatment was reduced considerably. Best medical advice from across the globe is available to the patient at less cost. Medical practitioners also stand to benefit as they can treat a variety of cases, collaborate among the medical fraternity and give consultation safely in case of fatal contagious diseases.

This study points to a definite growing popularity of telemedicine services not only in episodic patients but also chronic patients. Telemedicine with its unique advantages holds the promise to grow exponentially in the future and is a compelling health-care segment to focus on for delivering health-care solution to the geographically distant consumers.

Monocytes are a leukocytes’ subset that plays an important role in immunity. Protein kinase B (AKT) is involved in monocytes' survival, proliferation and differentiation. Using phorbol 12-myristate 13-acetate (PMA) as an inducer for cell line U937 differentiation into macrophage-like cells may be used as a model for cancer cell therapy or other biomedical research studies. The authors investigated the Akt1 signaling pathway's involvement with PMA as a differentiating agent and survival in the U937 cell line.

PMA was utilized to stimulate the differentiation of the U937 cell line into macrophage-like cells at a concentration of 10 nM. Akt1-phosphorylated Serine 473, Bad-phosphorylated Serine 136 and Caspase9-phosphorylated Serine 196 were tested by flow cytometry for the involvement of the Akt1 signaling pathway during differentiation in addition to the expression of CD14, CD206 and CD83. DNA cell cycle variation analysis was done using PI staining and cell viability and apoptosis detection using Annexin V and PI flow cytometry.

There was a decrease in phosphorylated Akt1 and Bad activation and an increase in Caspase9 activation, with an increase in surface markers CD14, CD206 and CD83 acquired by PMA-differentiated cells. DNA cell cycle analysis revealed cell accumulation in the G2/M phase and fewer cells in the S phase of PMA-induced U937. Apoptosis induction for Ly294002 or Wortmannin-inhibited cells and part of PMA-induced cells were detected.

These results may be used to create a model for biomedical research studies and advance the understanding of the mechanism involving differentiation of the U937 cell line.

Despite the growing interest regarding the Brazilian rice industry, there is not much literature focusing on the role of the institutions in the process of technological capability accumulation and in the formation of the technological trajectories within this industry. This paper aims to discover the role of local institutions in the generation and dissemination of knowledge for creating the technological capability that can define different technological trajectories, using the Brazilian rice industry as an empirical field.

To achieve said objective, this paper uses secondary data (documental research) and a multiple case study design based on primary empirical evidence (content analysis and direct observation) about the Brazilian rice industry.

The paper’s main contribution is the empirical application of a framework that allows us to evaluate the institutions’ roles and activities and how these capabilities evolve as the firms’ technological levels progress and the technological trajectory is formed. Regarding aspects related to public policy, the authors found some implications that are mainly related to the need to consolidate this type of institution in developing countries with the goal of strengthening its technological capabilities, allowing these countries to operate on the technological boundary and to compete with developed countries.

There are few attempts to relate the technological capability, technological trajectories and institutions in the Brazilian rice industry. Therefore, to the best of the authors’ knowledge, the novelty of this study lies in the analysis of these theoretical approaches in this industrial sector, more specifically, in the Brazilian rice industry.

The purpose of this study was to analyze importance of artificial intelligence (AI) in education and its emphasis on assessment and adversity quotient (AQ).

The study utilizes a systematic literature review of over 141 journal papers and psychometric tests to evaluate AQ. Thematic analysis of quantitative and qualitative studies explores domains of AI in education.

Results suggest that assessing the AQ of students with the help of AI techniques is necessary. Education is a vital tool to develop and improve natural intelligence, and this survey presents the discourse use of AI techniques and behavioral strategies in the education sector of the recent era. The study proposes a conceptual framework of AQ with the help of assessment style for higher education undergraduates.

Research on AQ evaluation in the Indian context is still emerging, presenting a potential avenue for future research. Investigating the relationship between AQ and academic performance among Indian students is a crucial area of research. This can provide insights into the role of AQ in academic motivation, persistence and success in different academic disciplines and levels of education. AQ evaluation offers valuable insights into how individuals deal with and overcome challenges. The findings of this study have implications for higher education institutions to prepare for future challenges and better equip students with necessary skills for success. The papers reviewed related to AI for education opens research opportunities in the field of psychometrics, educational assessment and the evaluation of AQ.

Smart urban governance research has progressed over the past few decades following changes and increasingly complicated city management difficulties. Therefore, the purpose of this paper is to use a scoping review and bibliometric analysis to examine all the publications on smart urban governance, especially in Asia.

A total of 1,900 smart urban governance articles indexed in the Scopus database was analyzed through scoping review and bibliometric analysis. The articles were analyzed by the number of publications per year, contributing countries, subject areas, authors, cited documents, related issues and cited papers. Furthermore, VOSviewer was used to provide a visual analysis of the co-occurrence of keywords.

This study indicated that urban smart governance publications continue to increase yearly. Even though the area of analysis is Asia, the USA and China seriously contributed to the analysis. Therefore, the topic of smart urban governance has become a discussion for scholars in the international. From the Scopus database analysis, the top three subject areas are social sciences (28%), environmental science (20%) and medicine (16%). The synthesis using bibliometric analysis by VOSviewer obtained 13 clusters.

This study only focuses on the Scopus database and one specific topic, using one bibliometric analysis tool. Meanwhile, national and international index databases are not used.

This paper examined publication trends on smart urban governance. This paper provided a comprehensive analysis of topic-specific knowledge areas based on previous studies. Additionally, this paper suggested the direction of the development of smart urban governance in the future.

Recently, powerful instruments for biomedical engineering research studies, including disease modeling, drug designing and nano-drug delivering, have been extremely investigated by researchers. Particularly, investigation in various microfluidics techniques and novel biomedical approaches for microfluidic-based substrate have progressed in recent years, and therefore, various cell culture platforms have been manufactured for these types of approaches. These microinstruments, known as tissue chip platforms, mimic in vivo living tissue and exhibit more physiologically similar vitro models of human tissues. Using lab-on-a-chip technologies in vitro cell culturing quickly caused in optimized systems of tissues compared to static culture. These chipsets prepare cell culture media to mimic physiological reactions and behaviors.

The authors used the application of lab chip instruments as a versatile tool for point of health-care (PHC) applications, and the authors applied a current progress in various platforms toward biochip DNA sensors as an alternative to the general bio electrochemical sensors. Basically, optical sensing is related to the intercalation between glass surfaces containing biomolecules with fluorescence and, subsequently, its reflected light that arises from the characteristics of the chemical agents. Recently, various techniques using optical fiber have progressed significantly, and researchers apply highlighted remarks and future perspectives of these kinds of platforms for PHC applications.

The authors assembled several microfluidic chips through cell culture and immune-fluorescent, as well as using microscopy measurement and image analysis for RNA sequencing. By this work, several chip assemblies were fabricated, and the application of the fluidic routing mechanism enables us to provide chip-to-chip communication with a variety of tissue-on-a-chip. By lab-on-a-chip techniques, the authors exhibited that coating the cell membrane via poly-dopamine and collagen was the best cell membrane coating due to the monolayer growth and differentiation of the cell types during the differentiation period. The authors found the artificial membrane, through coating with Collagen-A, has improved the growth of mouse podocytes cells-5 compared with the fibronectin-coated membrane.

The authors could distinguish the differences across the patient cohort when they used a collagen-coated microfluidic chip. For instance, von Willebrand factor, a blood glycoprotein that promotes hemostasis, can be identified and measured through these type-coated microfluidic chips.

The purpose of this paper is to investigate the efficacy of bacterial exopolysaccharides (Eps) in reactive black 5 (RB5) textile dye wastewater bioremediation.

The Eps were produced by bacteria isolated from cotton gin trash soils collected from different cotton-growing regions in Kenya for comparison purposes. A broth medium reconstituted using molasses was assessed for its capacity to produce the Eps. RB5 textile dye wastewater was optimized for dye removal under different temperatures, times and molasses concentrations. Dye removal was studied by Lovibond-Day Light Comparator, UV–Vis spectrophotometer and FTIR.

It was found that cotton gin trash soils contained Eps-producing bacteria. Three of the Eps studied were found to have the capacity to remove at least 80% of the dye from the wastewater.

This research did not assess the efficacy of the RB5 dye removal from the wastewater by mixtures of the Eps.

Bioremediation of textile dye wastewater with Eps produced by bacteria cultured from cotton gin trash soil is significant because it will offer an effective and cleaner alternative to the chemical coagulants.

Alternative treatment of textile wastewater with the Eps would result in safer water being released into the water bodies as opposed to the chemically treated wastewater that contains remnant chemicals.

Research on the use of Eps produced by bacteria isolated from cotton gin trash soils for removal of RB5 dye from textile wastewater has not been done before.