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The reliable transcranial imaging of brain inner structures for diagnostic purposes is deemed crucial owing to the decisive importance and contribution of the brain in human life. The purpose of this paper is to investigate the potential application of medical ultrasounds to transcranial imaging using advanced techniques, such as the total focussing method.

Initially, the fundamental details of the total focussing method are presented, while the skull properties, such as the increased acoustic velocity and scattering, are thoroughly examined. Although, these skull characteristics constitute the main drawback of typical transcranial ultrasonic propagation algorithms, they are exploited to focus the acoustic waves towards the brain. To this goal, a virtual source is designed, considering the wave refraction, to efficiently correct the reconstructed brain image. Finally, the verification of the novel method is conducted through numerical simulations of various realistic setups.

The theoretically designed virtual source resembles a focussed sensor; therefore, the directivity increment, owing to the propagation through the skull, is confirmed. Moreover, numerical simulations of real-world scenarios indicate that the typical artifacts of the conventional total focussing method are fully overcome because of the increased directivity of the proposed technique, while the reconstructed image is efficiently corrected when the proposed virtual source is used.

A new systematic methodology along with the design of a flexible virtual source is developed in this paper for the reliable and precise transcranial ultrasonic image reconstruction of the brain. Despite the slight degradation owing to the skull scattering, the combined application of the total focussing method and the featured virtual source can successfully detect arbitrary anomalies in the brain that cannot be spotted by conventional techniques.

To describe the utility of three of the main cognitive neuroscientific techniques currently in use within the neuroscience community, and how they can be applied to the emerging field of neuromarket research.

A brief development of functional magnetic resonance imaging, magnetoencephalography and transcranial magnetic stimulation are described, as the core principles are behind their respective use. Examples of actual data from each of the brain imaging techniques are provided to assist the neuromarketer with subsequent data for interpretation. Finally, to ensure the neuromarketer has an understanding of the experience of neuroimaging, qualitative data from a questionnaire exploring attitudes about neuroimaging techniques are included which summarize participants' experiences of having a brain scan.

Cognitive neuroscientific techniques have great utility in market research and can provide more “honest” indicators of consumer preference where traditional methods such as focus groups can be unreliable. These techniques come with complementary strengths which allow the market researcher to converge onto a specific research question. In general, participants considered brain imaging techniques to be relatively safe. However, care is urged to ensure that participants are positioned correctly in the scanner as incorrect positioning is a stressful factor during an imaging procedure that can impact data quality.

This paper is an important and comprehensive resource to the market researcher who wishes to use cognitive neuroscientific techniques.

Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique. Based on the unique functions of TMS, it has been widely used in clinical, scientific research and other fields. Nowadays, the robot-assisted automatic TMS has become the trend. In order to simplify the operation procedures of robotic TMS and reduce the costs, the purpose of this paper is to apply the marker-based augmented-reality technology to robotic TMS system.

By using the marker of ARToolKitPlus library and monocular camera, the patient’s head is positioned in real time. Furthermore, the force control is applied to keep contact between the coil and subject’s head.

The authors fuse with visual positioning which is based on augmented-reality and force-control technologies to track the movements of the patient’s head, bring the coil closer to the stimulation site and increase treatment effects. Experimental results indicate that the trajectory tracking control of robotic TMS system designed in this paper is practical and flexible.

This paper provides a trajectory tracking control method for the robotic TMS. The marker-based augmented-reality technology is implemented which simplifies the operation procedures of robotic TMS as well as reduce the costs. During the treatment process, the patients would wear an AR glasses, which can help patients relax through virtual scenes and reduce the uncomfortableness produce by treatment.

This paper aims to explore the relevant literature available regarding the use of repetitive transcranial magnetic stimulation (rTMS) as a mode of treatment for obsessive-compulsive disorder (OCD); to evaluate the evidence to support the use of rTMS as a treatment option for OCD.

The authors electronically conducted data search in five research databases (MEDLINE, CINAHL, Psych INFO, SCOPUS and EMBASE) using all identified keywords and index terms across all the databases to identify empirical studies and randomized controlled trials. The authors included articles published with randomized control designs, which aimed at the treatment of OCD with rTMS. Only full-text published articles written in English were reviewed. Review articles on treatment for conditions other than OCD were excluded. The Covidence software was used to manage and streamline the review.

Despite the inconsistencies in the published literature, the application of rTMS over the supplementary motor area and the orbitofrontal cortex has proven to be promising in efficacy and tolerability compared with other target regions such as the prefrontal cortex for the treatment of OCD. Despite the diversity in terms of the outcomes and clinical variability of the studies under review, rTMS appears to be a promising treatment intervention for OCD.

The authors of this scoping review acknowledge several limitations. First, the search strategy considered only studies published in English and the results are up to date as the last day of the electronic data search of December 10, 2020. Though every effort was made to identify all relevant studies for the purposes of this review per the eligibility criteria, the authors still may have missed some relevant studies, especially those published in other languages.

This review brought to bare the varying literature on the application of rTMS and what is considered gaps in the knowledge in this area in an attempt to evaluate and provide information on the potential therapeutic effects of rTMS for OCD.

The rapid progress of neuroscience and the interdisciplinary collaboration between neuroscience and psychology have begun to provide valuable insights for understanding the dynamic and implicit nature of human motivation by identifying the in vivo neural mechanism of motivation. One of the fundamental questions in the field of the neuroscience of motivation is what neural mechanisms underlie the direction, intensity, and guidance of our motivation and subsequent actions. This prologue explains how neuroscience can contribute to the understanding of human motivation. To accomplish this purpose, we present what neuroscientific data look like, identify 13 key motivation-relevant brain structures, and introduce 3 key motivation-centric brain circuits – namely, the reward circuit, the value-based decision-making pathway, and the self-regulation/self-control network.

The purpose of this paper is to explore the role of emotion in learning, specifically, e‐learning and its relationship to the phenomenon called energetic learning.

After first presenting operation definitions, the paper looks through the lens of new findings in neuroscience to build an understanding of the role of emotions in learning, then focuses specifically on how e‐learning systems contribute to energetic learning, providing examples of e‐learning platforms and software programs currently available that have specific attributes contributing to energetic learning.

With technology comes a natural excitement in terms of connectivity and its support of self‐driven, experiential learning which is part of the evolutionary heritage. As the understanding of the neuroscience and biology of human learning advances, the personal needs of individual learners are being begun to understand better. Bringing these needs together with e‐learning system capabilities will offer a significant jump in the learning rate and efficiency as we move into a future filled with change, uncertainty, complexity and anxiety.

The paper introduces the concept of energetic learning with specific focus on the contribution of e‐learning to energetic learning.

This study aims to investigate the effectiveness of two types of social media videos used for destination image development: induced/commercial-oriented content and organic content (where content is made without commercial interest, such as vlogs classified as user-generated content).

Experimental research using “Emotive EEG” (electroencephalogram) in a controlled environment was conducted with 30 participants (20 males, 10 females), age range 18 to 26. Emotive EEG recording was performed while the participants watched both types of video clips. Test results for both groups indicate that induced content is preferred over organic content.

This study opens up future research avenues where neuromarketing’s “Marketer Friendly” EEG equipment can be applied to the customer selection process.

Marketing analysts can gauge the interest and response of customers on different types of social media video content for destination marketing based on the findings of this study.

Through a review of historically famous cases and a chronicle of neurotechnology development, this chapter discusses brain structure and brain function as two distinct yet interrelated paths to understand the relative contributions of anatomical and physiological mechanisms to the human brain–behavior relationship. From an organizational neuroscience perspective, the chapter describes over a dozen neuroimaging technologies that are classified under four groupings: morphologic, invasive metabolic, noninvasive metabolic, and electromagnetic. We then discuss neuroimaging variables that may be useful in social science investigations, and we underscore electroencephalography as a particularly useful modality for the study of individuals and groups in organizational settings. The chapter concludes by considering emerging science and novel brain technologies for the organizational researcher as we look to the future.

Repetitive transcranial magnetic stimulation (rTMS) is a neurostimulatory technique used to modulate orbital frontal corticostriatal (OFC) activity and clinical symptomatology for psychiatric disorders involving OFC dysfunction. We examined the effectiveness of rTMS in the treatment of major depressive disorder in an applied clinical setting (Awakening KC CNI) to assess efficacy and optimize rTMS parameters within clinical practice. A retrospective review of medical records was carried out on patients with major depressive disorder undergoing rTMS therapy at Awakenings KC Clinical Neuroscience Institute (CNI), a suburban tertiary psychiatric clinic. A detailed de-identified data set of clinical outcomes was compiled. Patient Health Questionnaire 9 (PHQ-9) total score, clinical remission rate and week achieved were evaluated over 6 weeks of treatment to assess clinical response referencing two different rTMS instruments (MagVenture; NeuroStar). Our survey included 247 participants from males (N=98) and females (N=149) with average baseline PHQ-9 scores of 21.7±4, classified as severe depression. Clinically rated remission rates of 72% were achieved in 3.1±1.0 weeks and associated with prior history of psychiatric hospitalization, suicide attempts and substance use disorder. Average baseline PHQ-9 scores decreased significantly over time with proportionately greater remission rates achieved for patients treated using the MagVenture over NeuroStar instrument. rTMS in applied clinical practice is efficacious over a wide range of settings and patients. Clinical response was related to severity of depression symptoms (e.g., prior hospitalization; suicide attempts) validating efficacy in critically ill groups. Clinical response may be impacted by rTMS instrument, magnetic field parameters or individual factors.

Noninvasive brain stimulation (NIBS) such a transcranial magnetic stimulation, intermittent theta burst stimulation, transcranial direct current stimulation and electroconvulsive therapy have emerged as an efficacious and well-tolerated therapy for treatment-resistant psychiatric disorders. While novel NIBS techniques are an exciting addition to the current repertoire of neuropsychiatric therapies, their success is somewhat limited by the wide range of treatment responses seen among treated patients.

In this study, the authors will review the studies on relevant genetic polymorphisms and discuss the role of RNA genotyping in personalizing NIBS.

Genome studies have revealed several genetic polymorphisms that may contribute for the heterogeneity of treatment response to NIBS where the presence of certain single nucleotide polymorphisms (SNPs) are associated with responders versus nonresponders.

Historically, mental illnesses have been arguably some of the most challenging disorders to study and to treat because of the degree of biological variability across affected individuals, the role of genetic and epigenetic modifications, the diversity of clinical symptomatology and presentations and the interplay with environmental factors. In lieu of these challenges, there has been a push for personalized medicine in psychiatry that aims to optimize treatment response based on one’s unique characteristics.