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This chapter describes a number of research experiences of the authors, directed to increasing our understanding of exceptional individuals, most typically those with learning or behavioral disabilities. A number of examples is presented, to demonstrate how a research emphasis on exceptional persons can help to advance our understanding of human learning and cognition, and how such findings can contribute to the development of an overall, adequate theory of learning and instruction. Several general points from these experiences are presented, generally that the study of human exceptionality (a) can help to clarify our understanding of what we learn, and why we should learn it, (b) can enhance our understanding of what is “possible,” (c) demonstrate that what we do is more important than who we are, (d) demonstrate that we learn best by doing, and that our experience informs our understanding, and (e) demonstrate that we are all exceptional cases.

This chapter reports on the results from several extended qualitative investigations of co-teaching in science and social studies content area classes, on both elementary and secondary levels. In these investigations, co-teaching partners were studied and interviewed over several years, with the view of uncovering attitudes and procedures closely associated with successful collaborative partnerships. In some cases, these investigations took place in the context of implementation of research-based instructional strategies. Analysis of data from these investigations revealed that there was considerable variability in the way co-teaching practices were implemented, the attitudes toward co-teaching expressed by teachers, and the success of the co-teaching partnerships. It was thought that several variables, including content expertise, concerns for high-stakes testing, and the personal compatibility of co-teachers played an important role in the success of the co-teaching relationship.