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Interest in people who are ‘dangerous by way of severe personality disorder’ (DSPD) has grown enormously over the last six years, following growing concern in government about the lack of services for this challenging group. This has led to the development of an innovative programme and the piloting of new treatments. The DSPD Programme results from a partnership between the Home Office's National Offender Management Service and the Department of Health, and aims to pilot a range of approaches involving both prison and health service provision. Associated with this pilot is a research and development programme that will provide valuable findings on whether or not treatment can affect risks for individuals who have hitherto been considered difficult or impossible to treat.