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Article
Publication date: 14 May 2020

M.N. Doja, Ishleen Kaur and Tanvir Ahmad

The incidence of prostate cancer is increasing from the past few decades. Various studies have tried to determine the survival of patients, but metastatic prostate cancer is still…

Abstract

Purpose

The incidence of prostate cancer is increasing from the past few decades. Various studies have tried to determine the survival of patients, but metastatic prostate cancer is still not extensively explored. The survival rate of metastatic prostate cancer is very less compared to the earlier stages. The study aims to investigate the survivability of metastatic prostate cancer based on the age group to which a patient belongs, and the difference between the significance of the attributes for different age groups.

Design/methodology/approach

Data of metastatic prostate cancer patients was collected from a cancer hospital in India. Two predictive models were built for the analysis-one for the complete dataset, and the other for separate age groups. Machine learning was applied to both the models and their accuracies were compared for the analysis. Also, information gain for each model has been evaluated to determine the significant predictors for each age group.

Findings

The ensemble approach gave the best results of 81.4% for the complete dataset, and thus was used for the age-specific models. The results concluded that the age-specific model had the direct average accuracy of 83.74% and weighted average accuracy of 79.9%, with the highest accuracy levels for age less than 60.

Originality/value

The study developed a model that predicts the survival of metastatic prostate cancer based on age. The study will be able to assist the clinicians in determining the best course of treatment for each patient based on ECOG, age and comorbidities.

Details

Data Technologies and Applications, vol. 54 no. 2
Type: Research Article
ISSN: 2514-9288

Keywords

Open Access
Article
Publication date: 25 January 2023

Omran Alomran, Robin Qiu and Hui Yang

Breast cancer is a global public health dilemma and the most prevalent cancer in the world. Effective treatment plans improve patient survival rates and well-being. The five-year…

Abstract

Purpose

Breast cancer is a global public health dilemma and the most prevalent cancer in the world. Effective treatment plans improve patient survival rates and well-being. The five-year survival rate is often used to develop treatment selection and survival prediction models. However, unlike other types of cancer, breast cancer patients can have long survival rates. Therefore, the authors propose a novel two-level framework to provide clinical decision support for treatment selection contingent on survival prediction.

Design/methodology/approach

The first level classifies patients into different survival periods using machine learning algorithms. The second level has two models with different survival rates (five-year and ten-year). Thus, based on the classification results of the first level, the authors employed Bayesian networks (BNs) to infer the effect of treatment on survival in the second level.

Findings

The authors validated the proposed approach with electronic health record data from the TriNetX Research Network. For the first level, the authors obtained 85% accuracy in survival classification. For the second level, the authors found that the topology of BNs using Causal Minimum Message Length had the highest accuracy and area under the ROC curve for both models. Notably, treatment selection substantially impacted survival rates, implying the two-level approach better aided clinical decision support on treatment selection.

Originality/value

The authors have developed a reference tool for medical practitioners that supports treatment decisions and patient education to identify patient treatment preferences and to enhance patient healthcare.

Details

Digital Transformation and Society, vol. 2 no. 2
Type: Research Article
ISSN: 2755-0761

Keywords

Article
Publication date: 12 June 2017

Shabia Shabir Khan and S.M.K. Quadri

As far as the treatment of most complex issues in the design is concerned, approaches based on classical artificial intelligence are inferior compared to the ones based on…

Abstract

Purpose

As far as the treatment of most complex issues in the design is concerned, approaches based on classical artificial intelligence are inferior compared to the ones based on computational intelligence, particularly this involves dealing with vagueness, multi-objectivity and good amount of possible solutions. In practical applications, computational techniques have given best results and the research in this field is continuously growing. The purpose of this paper is to search for a general and effective intelligent tool for prediction of patient survival after surgery. The present study involves the construction of such intelligent computational models using different configurations, including data partitioning techniques that have been experimentally evaluated by applying them over realistic medical data set for the prediction of survival in pancreatic cancer patients.

Design/methodology/approach

On the basis of the experiments and research performed over the data belonging to various fields using different intelligent tools, the authors infer that combining or integrating the qualification aspects of fuzzy inference system and quantification aspects of artificial neural network can prove an efficient and better model for prediction. The authors have constructed three soft computing-based adaptive neuro-fuzzy inference system (ANFIS) models with different configurations and data partitioning techniques with an aim to search capable predictive tools that could deal with nonlinear and complex data. After evaluating the models over three shuffles of data (training set, test set and full set), the performances were compared in order to find the best design for prediction of patient survival after surgery. The construction and implementation of models have been performed using MATLAB simulator.

Findings

On applying the hybrid intelligent neuro-fuzzy models with different configurations, the authors were able to find its advantage in predicting the survival of patients with pancreatic cancer. Experimental results and comparison between the constructed models conclude that ANFIS with Fuzzy C-means (FCM) partitioning model provides better accuracy in predicting the class with lowest mean square error (MSE) value. Apart from MSE value, other evaluation measure values for FCM partitioning prove to be better than the rest of the models. Therefore, the results demonstrate that the model can be applied to other biomedicine and engineering fields dealing with different complex issues related to imprecision and uncertainty.

Originality/value

The originality of paper includes framework showing two-way flow for fuzzy system construction which is further used by the authors in designing the three simulation models with different configurations, including the partitioning methods for prediction of patient survival after surgery. Several experiments were carried out using different shuffles of data to validate the parameters of the model. The performances of the models were compared using various evaluation measures such as MSE.

Details

International Journal of Intelligent Computing and Cybernetics, vol. 10 no. 2
Type: Research Article
ISSN: 1756-378X

Keywords

Open Access
Article
Publication date: 3 February 2021

Geoff A.M. Loveman and Joel J.E. Edney

The purpose of the present study was the development of a methodology for translating predicted rates of decompression sickness (DCS), following tower escape from a sunken…

Abstract

Purpose

The purpose of the present study was the development of a methodology for translating predicted rates of decompression sickness (DCS), following tower escape from a sunken submarine, into predicted probability of survival, a more useful statistic for making operational decisions.

Design/methodology/approach

Predictions were made, using existing models, for the probabilities of a range of DCS symptoms following submarine tower escape. Subject matter expert estimates of the effect of these symptoms on a submariner’s ability to survive in benign weather conditions on the sea surface until rescued were combined with the likelihoods of the different symptoms occurring using standard probability theory. Plots were generated showing the dependence of predicted probability of survival following escape on the escape depth and the pressure within the stricken submarine.

Findings

Current advice on whether to attempt tower escape is based on avoiding rates of DCS above approximately 5%–10%. Consideration of predicted survival rates, based on subject matter expert opinion, suggests that the current advice might be considered as conservative in the distressed submarine scenario, as DCS rates of 10% are not anticipated to markedly affect survival rates.

Originality/value

According to the authors’ knowledge, this study represents the first attempt to quantify the effect of different DCS symptoms on the probability of survival in submarine tower escape.

Details

Journal of Defense Analytics and Logistics, vol. 5 no. 1
Type: Research Article
ISSN: 2399-6439

Keywords

Article
Publication date: 12 October 2021

Marina Johnson, Abdullah Albizri, Antoine Harfouche and Salih Tutun

The global health crisis represents an unprecedented opportunity for the development of artificial intelligence (AI) solutions. This paper aims to integrate explainable AI into…

Abstract

Purpose

The global health crisis represents an unprecedented opportunity for the development of artificial intelligence (AI) solutions. This paper aims to integrate explainable AI into the decision-making process in emergency scenarios to help mitigate the high levels of complexity and uncertainty associated with these situations. An AI solution is designed to extract insights into opioid overdose (OD) that can help government agencies to improve their medical emergency response and reduce opioid-related deaths.

Design/methodology/approach

This paper employs the design science research paradigm as an overarching framework. Open-access digital data and AI, two essential components within the digital transformation domain, are used to accurately predict OD survival rates.

Findings

The proposed AI solution has two primary implications for the advancement of informed emergency management. Results show that it can help not only local agencies plan their resources for timely response to OD incidents, thus improving survival rates, but also governments to identify geographical areas with lower survival rates and their primary contributing factor; hence, they can plan and allocate long-term resources to increase survival rates and help in developing effective emergency-related policies.

Originality/value

This paper illustrates that digital transformation, particularly open-access digital data and AI, can improve the emergency management framework (EMF). It also demonstrates that the AI models developed in this study can identify opioid OD trends and determine the significant factors improving survival rates.

Details

Industrial Management & Data Systems, vol. 123 no. 1
Type: Research Article
ISSN: 0263-5577

Keywords

Article
Publication date: 2 April 2021

George Besseris and Panagiotis Tsarouhas

The study aims to provide a quick-and-robust multifactorial screening technique for early detection of statistically significant effects that could influence a product's life-time…

Abstract

Purpose

The study aims to provide a quick-and-robust multifactorial screening technique for early detection of statistically significant effects that could influence a product's life-time performance.

Design/methodology/approach

The proposed method takes advantage of saturated fractional factorial designs for organizing the lifetime dataset collection process. Small censored lifetime data are fitted to the Kaplan–Meier model. Low-percentile lifetime behavior that is derived from the fitted model is used to screen for strong effects. A robust surrogate profiler is employed to furnish the predictions.

Findings

The methodology is tested on a difficult published case study that involves the eleven-factor screening of an industrial-grade thermostat. The tested thermostat units are use-rate accelerated to expedite the information collection process. The solution that is provided by this new method suggests as many as two active effects at the first decile of the data which improves over a solution provided from more classical methods.

Research limitations/implications

To benchmark the predicted solution with other competing approaches, the results showcase the critical first decile part of the dataset. Moreover, prediction capability is demonstrated for the use-rate acceleration condition.

Practical implications

The technique might be applicable to projects where the early reliability improvement is studied for complex industrial products.

Originality/value

The proposed methodology offers a range of features that aim to make the product reliability profiling process faster and more robust while managing to be less susceptible to assumptions often encountered in classical multi-parameter treatments.

Details

International Journal of Quality & Reliability Management, vol. 39 no. 1
Type: Research Article
ISSN: 0265-671X

Keywords

Article
Publication date: 10 December 2020

S. Gomathi, Rashi Kohli, Mukesh Soni, Gaurav Dhiman and Rajit Nair

Since December 2019, global attention has been drawn to the rapid spread of COVID-19. Corona was discovered in India on 30 January 2020. To date, in India, 178,014 disease cases…

Abstract

Purpose

Since December 2019, global attention has been drawn to the rapid spread of COVID-19. Corona was discovered in India on 30 January 2020. To date, in India, 178,014 disease cases were reported with 14,011 deaths by the Indian Government. In the meantime, with an increasing spread speed, the COVID-19 epidemic occurred in other countries. The survival rate for COVID-19 patients who suffer from a critical illness is efficiently and precisely predicted as more fatal cases can be affected in advanced cases. However, over 400 laboratories and clinically relevant survival rates of all present critically ill COVID-19 patients are estimated manually. The manual diagnosis inevitably results in high misdiagnosis and missed diagnosis owing to a lack of experience and prior knowledge. The chapter presents an option for developing a machine-based prognostic model that exactly predicts the survival of individual severe patients with clinical data from different sources such as Kaggle data.gov and World Health Organization with greater than 95% accuracy. The data set and attributes are shown in detail. The reasonableness of such a mere three elements may depend, respectively, on their representativeness in the indices of tissue injury, immunity and inflammation. The purpose of this paper is to provide detailed study from the diagnostic aspect of COVID-19, the work updates the cost-effective and prompt criticality classification and prediction of survival before the targeted intervention and diagnosis, in particular the triage of the vast COVID-19 explosive epidemic.

Design/methodology/approach

Automated machine learning (ML) provides resources and platforms to render ML available to non-ML experts, to boost efficiency in ML and to accelerate research in machine learning. H2O AutoML is used to generate the results (Dulhare et al., 2020). ML has achieved major milestones in recent years, and it is on which an increasing range of disciplines depend. But this performance is crucially dependent on specialists in human ML to perform the following tasks: preprocess the info and clean it; choose and create the appropriate apps; choose a family that fits the pattern; optimize hyperparameters for layout; and models of computer learning post processes. Review of the findings collected is important.

Findings

These days, the concept of automated ML techniques is being used in every field and domain, for example, in the stock market, education institutions, medical field, etc. ML tools play an important role in harnessing the massive amount of data. In this paper, the data set relatively holds a huge amount of data, and appropriate analysis and prediction are necessary to track as the numbers of COVID cases are increasing day by day. This prediction of COVID-19 will be able to track the cases particularly in India and might help researchers in the future to develop vaccines. Researchers across the world are testing different medications to cure COVID; however, it is still being tested in various labs. This paper highlights and deploys the concept of AutoML to analyze the data and to find the best algorithm to predict the disease. Appropriate tables, figures and explanations are provided.

Originality/value

As the difficulty of such activities frequently goes beyond non-ML-experts, the exponential growth of ML implementations has generated a market for off-the-shelf ML solutions that can be used quickly and without experience. We name the resulting work field which is oriented toward the radical automation of AutoML machine learning. The third class is that of the individuals who have illnesses such as diabetes, high BP, asthma, malignant growth, cardiovascular sickness and so forth. As their safe frameworks have been undermined effectively because of a common ailment, these individuals become obvious objectives. Diseases experienced by the third classification of individuals can be lethal (Shinde et al., 2020). Examining information is fundamental in having the option to comprehend the spread and treatment adequacy. The world needs a lot more individuals investigating the information. The understanding from worldwide data on the spread of the infection and its conduct will be key in limiting the harm. The main contributions of this study are as follows: predicting COVID-19 pandemic in India using AutoML; analyzing the data set predicting the patterns of the virus; and comparative analysis of predictive algorithms. The organization of the paper is as follows, Sections I and II describe the introduction and the related work in the field of analyzing the COVID pandemic. Section III describes the workflow/framework for AutoML using the components with respect to the data set used to analyze the patterns of COVID-19 patients.

Details

World Journal of Engineering, vol. 19 no. 1
Type: Research Article
ISSN: 1708-5284

Keywords

Article
Publication date: 8 August 2016

Skender Buci and Agim Kukeli

The purpose of this paper is to assess the survival probability among patients with liver trauma injury using the anatomical and psychological scores of conditions…

677

Abstract

Purpose

The purpose of this paper is to assess the survival probability among patients with liver trauma injury using the anatomical and psychological scores of conditions, characteristics and treatment modes.

Design/methodology/approach

A logistic model is used to estimate 173 patients’ survival probability. Data are taken from patient records. Only emergency room patients admitted to University Hospital of Trauma (former Military Hospital) in Tirana are included. Data are recorded anonymously, preserving the patients’ privacy.

Findings

When correctly predicted, the logistic models show that survival probability varies from 70.5 percent up to 95.4 percent. The degree of trauma injury, trauma with liver and other organs, total days the patient was hospitalized, and treatment method (conservative vs intervention) are statistically important in explaining survival probability.

Practical implications

The study gives patients, their relatives and physicians ample and sound information they can use to predict survival chances, the best treatment and resource management.

Originality/value

This study, which has not been done previously, explores survival probability, success probability for conservative and non-conservative treatment, and success probability for single vs multiple injuries from liver trauma.

Details

International Journal of Health Care Quality Assurance, vol. 29 no. 7
Type: Research Article
ISSN: 0952-6862

Keywords

Article
Publication date: 1 June 2002

Robert Hamilton, Barry Howcroft, Zhonghua Liu and Keith Pond

Outlines the UK law on insovency and asks whether the financial ratios banks use to assess credit worthiness can discriminate between the companies placed in administrative…

598

Abstract

Outlines the UK law on insovency and asks whether the financial ratios banks use to assess credit worthiness can discriminate between the companies placed in administrative receivership (AR) by their lending banks which can or cannot be rescued. Applies both linear discriminant analysis and logistic regression to samples of UK companies placed into AR in 1998, explains the methodology and shows broadly similar results from the two methods; and a predictive accuracy of 85‐90 per cent for the rescued companies and 55‐60 per cent for the failures. Analyses the key ratios for survival in more detail, looking at debtor turnover, the gearing ratio and the current ratio. Recogises the limitations of the study but sees it as a promising approach to predicting survivability.

Details

Managerial Finance, vol. 28 no. 6
Type: Research Article
ISSN: 0307-4358

Keywords

Article
Publication date: 1 April 2001

Patti Cybinski

This paper describes a number of models used in bankruptcy studies to date. They arise from two basic model designs used in studies of financial distress: cross-sectional studies…

1556

Abstract

This paper describes a number of models used in bankruptcy studies to date. They arise from two basic model designs used in studies of financial distress: cross-sectional studies that compare healthy and distressed firms, and time-series formulations that study the path to failure of (usually) distressed firms only. These two designs inherently foster different research objectives. Different instances of the most recent work taken from each of the above research groups, broadly categorized by design, are described here including new work by this author. It is argued that those that investigate the distress continuum with predominantly explanatory objectives are superior on a number of criteria to the studies that follow what is essentially a case-control structure and espouse prediction as their objective.

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