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This is the third in a series of papers aimed at providing models effective in predicting the degree of pain and discomfort in canines. The first two papers provided benchmarking and examination of dogs suffering from osteoarthritis (OA). In this chapter, we extend the study to include dogs suffering from OA, sarcoma, and oral mucositis (a side effect of chemotherapy and radiation treatments). The R programming language and SAS JMP are used to clean data, generate ANOVA, LSR regression, decision tree, and nominal logistic regression models to predict changes in activity levels associated with the progression of arthritis. The predictive models provide a diagnostic basis for determining the degree of disease in a dog (based on demographics and activity levels) and provide forecasts that assist in establishing appropriate medication dosages for suffering dogs.

The railway track system is the platform by which loads from moving trains are transferred to the underlying soil or supporting infrastructure such as bridges. The most common type of railway track system is ballasted track, which has been in use for over a century. Ballasted track has proved versatile. It can be constructed using locally available materials and with modifications to the rails and sleepers, crossings transferring trains from one route to another can be created. The structure of a ballasted track system consists of two main parts. The upper portion, termed the superstructure, comprises the rails, fastenings and sleepers. It is formed of components whose shape, stiffness and strength are designed and closely controlled. Below the superstructure is the substructure, which comprises the ballast and sub-ballast. Although the materials used in the substructure may have been specified, their engineering properties and geometric placement are less well controlled. In this chapter, we will explore how a typical ballasted track system transfers load to the ground and the ways in which the track form deteriorates, requiring maintenance and eventually renewal.

Earthworks are the embankments and cuttings that allow a railway to maintain a certain line, level and grade through the landscape. Earth embankments consist of an engineered bank of earth that carries the railway above the natural ground. A cutting is used to carry the railway through ground with a natural level above the line of the railway. Modern (post 1960s) earthworks are carefully engineered to perform well. However, many railways run on earthworks that were constructed over 100 years ago without the use of mechanised plant. The quality of construction of older earthworks was often poor compared with present-day engineering practice. Ageing of the earthwork structures, and the greater demands of heavier and faster trains and climatic change, means that earthworks suffer ultimate and serviceability failures that can present operational difficulties. Older earthworks that fail or do not perform well require maintenance and repair, and sometimes complete replacement. This chapter explores the main engineering considerations for modern earthworks, and the challenges associated with older earthworks including their modes of failure and upgrade and repair.

This study proposes targeted modernization of the Department of Defense (DoD's) Joint Forces Ammunition Logistics information system by implementing the optimized innovative information technology open architecture design and integrating Radio Frequency Identification Device data technologies and real-time optimization and control mechanisms as the critical technology components of the solution. The innovative information technology, which pursues the focused logistics, will be deployed in 36 months at the estimated cost of $568 million in constant dollars. We estimate that the Systems, Applications, Products (SAP)-based enterprise integration solution that the Army currently pursues will cost another $1.5 billion through the year 2014; however, it is unlikely to deliver the intended technical capabilities.

This chapter describes the approach to sustainable rail passenger rolling stock in terms of interior passive safety requirements within the European market. It is intended to give the background and logistical approach for the future introduction of a standard as an aid for the design and validation of the interiors of passenger rail vehicles. Also discussed is the acceptance of the proposed European-based standard into the regulatory system of the technical specifications for interoperability. Methodologies for design assessment and validation will be discussed. This chapter is intended to encourage an acceptance of the standard for interior passive safety as a realistic and cost-effective method of improving rail vehicle safety in terms of the passenger interfaces with the rail stock interior.