Search results

The paper aims to promote the development of intelligent materials and the 4D printing technology by introducing recent advances and applications of additive layered manufacturing (ALM) technology of intelligent materials and the development of the 4D printing technology. Also, an arm-type ALM technology of shape memory polymer (SMP) with thermosetting polyurethane is briefly introduced.

This paper begins with an overview of the development and applications of intelligent materials around the world and the 4D printing technology. Then, the authors provide a brief outline of their research on arm-type ALM technology of SMP with thermosetting polyurethane.

The paper provides the recent developments and applications of intelligent materials and 4D printing technology. Then, it is suggested that intelligent materials mixed with different functional materials will be developed, and these types of materials will be more suitable for 4D printing.

This paper overviews the current developments and applications of intelligent materials and its use in 4D printing technology, and briefly states the authors’ research on arm-type ALM technology of SMP with thermosetting polyurethane.

Alzheimer’s disease (AD), the most common cause of dementia, is a neurodegenerative disorder caused by the aggregation of amyloid-beta (Aβ) at outside of neuron cells and also due to tau aggregation inside the cell. Corosolic acid is aimed to be selected as a main active constituent of Lagerstroemia speciosa for the study.

In the present study, molecular docking of corosolic acid and tau protein was examined using PyRx-v.0.8 software. Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) properties were described and a molecular dynamics study of the bound complex was performed using Desmond.

The docking score and interactions suggested that the corosolic acid (CID:6918774) could bind to tau protein to prevent the fibrillar network, to prevent AD. During simulation corosolic acid-bound protein root mean square deviation (RMSD) values showed more stability when compared to the Apo form of protein. Molecular dynamics study of tau protein and corosolic acid complex gave the insights to develop a drug-like candidate against AD.

The use of corosolic acid of Lagerstroemia speciosa to prevent AD is supported by preliminary analysis on a computational basis. This compound should explore in terms of experimental strategies for the further drug development process. However, in vitro and in vivo evaluation studies are required to suggest the use of corosolic acid against AD.

An Autodesk Ember three-dimensional (3D) printer was used to print optical components from Clear PR48 photocurable resin. The cured PR48 was characterized by the per cent of light transmitted and the index of refraction, which was measured with a prism spectrometer. Lenses and diffraction gratings were also printed and characterized. The focal length of the printed lenses agreed with predictions based on the thin lens equation. The periodicity and effective slit width of the printed gratings were determined from both optical micrographs and fits to the Fraunhofer diffraction equation. This study aims to demonstrate the advantages offered by a layer-by-layer DLP printing process for the manufacture of optical components for use in the visible region of the electromagnetic spectrum.

A 3D printer was used to print both lenses and diffraction gratings from Standard Clear PR48 photocurable resin. The manufacturing process of the lenses and the diffraction gratings differ mainly in the printing angle with respect to the printer x-y-axes. The transmission diffraction gratings studied here were manufactured with nominal periodicities of 10, 25 and 50 µm. The aim of this study was to optically determine the effective values for the distance between slits, d, and the effective width of the slits, w, and to compare these values with the printed layer thickness.

The normalized diffraction patterns measured in this experiment for the printed gratings with layer thickness of 10, 25 and 50 µm are shown by the solid dots in Figures 8(a)-(c). Also shown as a red solid line are the fits to the experimental diffraction data. The effective values of d and w obtained from fitting the data are compared to the nominal layer thickness of the printed gratings. The effective distance between slits required to fit the diffraction patterns are well approximated by the printed layer thickness to within 14, 4 and 16 per cent for gratings with a nominal 10, 25 and 50 µm layer thickness, respectively.

Chromatic aberration is present in all polymer lenses, and the authors have not attempted to characterize it in this study. These materials could be used for achromatic lenses if paired with a crown-type material in an achromatic doublet configuration, because this would correct the chromatic aberration issues. It is worthwhile to compare the per cent transmission in cured PR48 resin (approximately 80 per cent) to the percent transmission found in common optical materials like BK7 (approximately 92 per cent) over the visible region. The authors attribute the lower transmission in PR48 to a combination of surface scattering and increased absorption. At the present time, the authors do not know what fraction of the lower transmission is related to the surface quality resulting from sample polishing.

There are inherent limitations to the 3D manufacturing process that affect the performance of lenses. Approximations to a curved surface in the design software, the printing resolution of the Autodesk Ember printer and the anisotropy due to printing in layers are believed to be the main issues. The performance of the lenses is also affected by internal imperfections in the printed material, in particular the presence of bubbles and the inclusion of debris like dust or fibers suspended in air. In addition, the absorption of wavelengths in the blue/ultraviolet produces an undesirable yellowing in any printed part.

One of the most interesting results from this study was the manufacture of diffraction gratings using 3D printing. An analysis of the diffraction pattern produced by these printed gratings yielded estimates for the slit periodicity and effective slit width. These gratings are unique because the effective slit width fills the entire volume of the printed part. This aspect makes it possible to integrate two or more optical devices in a single printed part. For example, a lens combined with a diffraction grating now becomes possible.

The purpose of this paper is to identify the compensation between research groups and companies that contribute the most for the innovative performance of Brazilian public higher educational institutions (PHEI), using as database the 2010’s tabular plan from CNPq’s Directory of Research Groups.

Descriptive and multivariate statistical techniques such as spearman correlation, cluster analysis, ANOVA and discriminant analysis were used.

Compensations that contribute the most for the updating of the PHEI are identified as transfer of financial resources from the partner to the group; providing grants for the group; transfer of material supplies to partner’s activities; temporary physical transfer of human resources from the group to the activities conducted by the partner; other forms of compensation that do not fit in the previous categories; and partnering with transfers of resources of any kind going in any direction.

As a limitation, it is pointed out the discontinuity of the tabular plan, which presents 2010 as the last available data.

The results can contribute to programs and policies to encourage innovation within universities.

It may be inferred that the stimulus to specific compensations may expand the quantitative idea of interaction points between the university and companies, linking qualitative aspects, which leads to an understanding that such interactions may, in fact, contribute directly to the activity of generating and spreading knowledge and innovation.