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The aim of this paper is to present results of a foresight study on identifying priorities for health-related research and development (R&D) in Russia for the period until 2030.

Research priorities were identified through consistent integrated expert analysis and evaluation of the subject area, i.e. biomedical research preceding development of medical technologies.

Key global and national trends in the biomedical R&D sector and related areas (medicine and health) were identified. According to the experts, the following markets have the best prospects for Russia: regenerative medicine, biodegradable and other biocompatible materials, diagnostic systems, implants, surgical equipment, targeted delivery systems and non-invasive visualisation systems. Entering these markets requires providing support to R&D in the following areas: promising drug candidates, molecular diagnostics, molecular profiling and mechanisms of human diseases, cell technologies (therapies), new materials (biomimetics and other), bioelectronic, bioimaging and biosensors and human genome databases.

Regularly updating research priorities is a necessary prerequisite of successful science and technology development of countries, innovative companies and academic institutions. Allocation of (always limited) financial resources on the basis of such priority-setting exercises’ results is evidence of adherence to scientific planning principles. Combined with monitoring and evaluation tools, priority setting for biomedical R&D must become an integral component of Russia’s innovation policy.

This is a first-ever presentation of Russian experience in setting research priorities for the health-related sphere. Global and national contexts for development of biomedical R&D are described; markets and research areas with the biggest potential for Russian companies are identified.

In February this year the sequence of the human genome was published, opening a new chapter in medicine. Soon genetic testing will be at the heart of diagnosis, epidemiology, drug development and even regenerative medicine. Before we are born there will be new opportunities to remedy genetic defects, and afterwards to make almost lifelong prognoses. The debate will intensify on the use of human embryos in medical research, while the prospect of human cloning will fascinate some scientists and horrify others. Europe needs to be in the vanguard of this new industrial revolution, but a host of ethical concerns must first be addressed – because genomics is as much about privacy as Petri dishes.

The research analyzes good practices in health care “management experimentation models,” which fall within the broader range of the integrative public–private partnerships (PPPs). Introduced by the Italian National Healthcare System in 1991, the “management experimentation models” are based on a public governance system mixed with a private management approach, a patient-centric orientation, a shared financial risk, and payment mechanisms correlated with clinical outcomes, quality, and cost-savings. This model makes public hospitals more competitive and efficient without affecting the principles of universal coverage, solidarity, and equity of access, but requires higher financial responsibility for managers and more flexibility in operations.

In Italy the experience of such experimental models is limited but successful. The study adopts the case study methodology and refers to the international collaboration started in 1997 between two Italian hospitals and the University of Pittsburgh Medical Center (UPMC – Pennsylvania, USA) in the field of organ transplants and biomedical advanced therapies.

The research allows identifying what constitutes good management practices and factors associated with higher clinical performance. Thus, it allows to understand whether and how the management experimentation model can be implemented on a broader basis, both nationwide and internationally. However, the implementation of integrative PPPs requires strategic, cultural, and managerial changes in the way in which a hospital operates; these transformations are not always sustainable.

The recognition of ISMETT’s good management practices is useful for competitive benchmarking among hospitals specialized in organ transplants and for its insights on the strategies concerning the governance reorganization in the hospital setting. Findings can be used in the future for analyzing the cross-country differences in productivity among well-managed public hospitals.

In this paper we present preliminary findings from a study of the social, ethical and cultural aspects of ageing science and medicine. The paper draws on a collaborative, ongoing project between life scientists and sociologists, funded by the Economic and Social Research Council's (ESRC) New Dynamics of Ageing Programme1 and the ESRC Centre for the Economic and Social Aspects of Genomics2. The sociological element of this project involves participant observation and interviews with expert scientists who specialise in ageing and age‐related diseases, both in the UK and the US, as well as interviews with sceptics of ageing science and medicine. There has been much critique of how ageing science is anti‐ageing, reinforcing the ageism prevalent in Western culture. Our specific objective in this paper is to suggest how biogerontology can contribute to the social inclusion of older people, particularly in relation to health care. We discuss how agesim is endemic to some aspects of health care, and go on to show how the ways that biogerontology is reconceptualising what it is to age, and to be old, can help reinclude ageing and the aged in health‐care education, policy and practice.

The purpose of this paper is to discuss different 3D printing techniques and also illustrate the issues related to 3D printing and cost-effectiveness in the near future.

A systematic literature review methodology is adopted for this review paper. 3D printing is in the initial phase of implementation in healthcare; therefore, a study of 70 research papers is done, which discusses the research trends of 3D printing in healthcare sector from 2007 to mid-2018.

Though additive manufacturing has a vast application, it has not been used to its full potential. Therefore, more research is required in that direction. It is revealed from the review that only a few researchers have explored issues related to cost, which can clearly show cost-effectiveness of adopting 3D printing.

This paper helps in understanding the different 3D printing techniques and their application in the healthcare. It also proposed some methods which can be applied in delivering customized pharmaceuticals to the customer and to improve surgery.

The authors contribute to the literature on leadership by investigating how characteristics of principal investigators (PIs) affect innovation performance, and how collaborative and non-collaborative projects moderate this relationship within the context of inter-organisational research projects.

The authors analysed panel data from the National Science and Technology Information Service on 171 research projects within a biomedical and regenerative medicines programme overseen by the Korea Health Industry Development Institute. The authors used a hierarchical regression model, based on the ordinary least squares method, to examine the relationship between PI characteristics and performance, considering both quantity and quality.

The results show that the characteristics of PIs have diverse effects on the quantity and quality of innovation performance. Gender diversity within PIs negatively affects the quality of innovation performance, while the capacity of PIs positively influences it. Moreover, the degree of PI’s engagement is positively associated with the quantity of innovation performance but does not have a significant relationship with the quality of performance. In terms of moderating effects, collaborative projects with multiple leaders seem less reliant on PI capacity than non-collaborative projects led by a single leader, in terms of innovation performance.

The results contribute significantly to the literature on innovation management by examining the role of leadership in collaborative environments to enhance innovation performance, addressing the need for empirical evidence in this area. Analyses of PI characteristics in government R&D management can lead to improved team performance, more efficient processes and effective resource allocation, ultimately fostering innovation.

To introduce recent research and development of biopolymer deposition for freeform fabrication of three‐dimensional tissue scaffolds that is capable of depositing bioactive ingredients.

A multi‐nozzle biopolymer deposition system is developed, which is capable of extruding biopolymer solutions and living cells for freeform construction of 3D tissue scaffolds. The deposition process is biocompatible and occurs at room temperature and low pressures to reduce damage to cells. In contrast with other systems, this system is capable of, simultaneously with scaffold construction, depositing controlled amount of cells, growth factors, or other bioactive compounds with precise spatial position to form complex cell‐seeded tissue constructs. The examples shown are based on sodium alginate solutions and poly‐ε‐caprolactone (PCL). Studies of the biopolymer deposition feasibility, structural formability, and different material deposition through a multi‐nozzle heterogeneous system are conducted and presented.

Provides information about the biopolymer deposition using different nozzle systems, the relations of process parameters on deposition flow rate and scaffold structural formability. Three‐dimensional alginate‐based scaffolds and scaffold embedded with living cells can be freeform constructed according to various design configurations at room temperature without using toxic materials.

Other biopolymers may also be studied for structure formation. Studying cell viability and cellular tissue engineering behavior of the scaffolds after the cell deposition should be further investigated.

A very useful and effective tool for construction of bioactive scaffolds for tissue engineering applications based on a multi‐nozzle biopolymer deposition.

This paper describes a novel process and manufacturing system for fabrication of bioactive tissue scaffolds, automatic cell loading, and heterogeneous tissue constructs for emerging regenerative medicine.