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Article
Publication date: 22 March 2013

Encapsulation efficiency of coenzyme Q10‐liposomes in alginate

Phornsinee Sakchareonkeat, Tzou‐Chi Huang, Prisana Suwannaporn, Yu Hsuan Chiang, Jue Liang Hsu and Yong Han Hong

The purpose of this study is to evaluate the effectiveness of alginate as a vehicle to protect coenzyme Q10 in liposomes.

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Abstract

Purpose

The purpose of this study is to evaluate the effectiveness of alginate as a vehicle to protect coenzyme Q10 in liposomes.

Design/methodology/approach

Encapsulation efficiency and stability were conducted at varying temperatures (20, 30, 40°C) for 5 d and at exposure to simulated gastric conditions (pH 2) for 2 h. The content of coenzyme Q10 was determined using HPLC (LC/MS). Cytotoxicity and phagocytosis of mouse macrophages (RAW264.7) was determined.

Findings

Results showed that thermostability was strongly improved by alginate complex formation with liposomes. Moreover, alginate could maintain coenzyme Q10 at a significantly higher level in simulated gastric pH for at least 2 h (p<0.00).

Practical implications

This allowed a higher amount of coenzyme Q10 remaining to be absorbed in the small intestine. Alginate not only showed no toxic effect on mouse macrophages but also activated their proliferation and phagocytosis ability.

Originality/value

As a consequence, alginate could be applied as an aid to encapsulation stability and immunostimulating potency.

Details

Nutrition & Food Science, vol. 43 no. 2
Type: Research Article
DOI: https://doi.org/10.1108/00346651311313463
ISSN: 0034-6659

Keywords

  • Alginate
  • Liposome
  • Coenzyme Q10
  • Encapsulation
  • Cytotoxicity
  • Phagocytosis
  • Nutrition
  • Heat

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Book part
Publication date: 13 October 2017

SMEs and Green Growth: The Effectiveness of Support Mechanisms and Initiatives Matters

Panagiotis Liargovas, Nikolaos Apostolopoulos, Ilias Pappas and Alexandros Kakouris

The aim of this chapter is to examine the way in which small- and medium-sized enterprises (SMEs) adapt their financial and operational planning in order to develop green…

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Abstract

The aim of this chapter is to examine the way in which small- and medium-sized enterprises (SMEs) adapt their financial and operational planning in order to develop green entrepreneurship. This is examined through two different practices which may be followed by companies: policies and strategies that lead enterprises to energy upgrade and policies and strategies relating to environmental protection. This chapter draws upon the dataset from 100 Greek SMEs. The process of data collection was conducted by delivering questionnaires to the sample of companies in question. The novelty of this research, in comparison with other surveys, is that the level of adopting green strategies is approached not only in the fields of energy or environmental efficiencies but also attempts to introduce techno-economic parameters with related items in the questionnaires delivered to the SMEs. Hence, a more thorough analysis for the greenness of Greek SMEs is discussed based on 10 (i.e. techno-economic) research hypotheses. The results indicate that the SMEs should be supported more effectively by the Greek government and European Union through funding initiatives. The funding initiatives do not have the expected results so far towards this direction. However, it seems that the SMEs realize the importance of green strategies as they believe the consumers are willing to pay more for green products.

Details

Green Economy in the Western Balkans
Type: Book
DOI: https://doi.org/10.1108/978-1-78714-499-620171004
ISBN: 978-1-78714-499-6

Keywords

  • Green strategies
  • SMEs
  • entrepreneurship
  • Greece

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Article
Publication date: 14 March 2016

Using modified IPA to define quality improvement strategies: A study of air-conditioning industry in Taiwan

Li-Hsing Ho, Pi-Yun Chang and Tieh-Min Yen

The purpose of this paper is to propose a modified Importance-Performance Analysis (IPA) model and calculates the performance of quality characteristic for the purpose of…

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Abstract

Purpose

The purpose of this paper is to propose a modified Importance-Performance Analysis (IPA) model and calculates the performance of quality characteristic for the purpose of defining quality improvement strategy.

Design/methodology/approach

This study developed modified IPA by introducing the Mahalanobis Distance and multiple regression analysis to evaluate the performance gap and implicit importance of quality characteristics. This paper used a large air-conditioning manufacturer in Taiwan as the case analysis and study targets. It discussed and validated the modified IPA analytical results by studying case history and market analysis.

Findings

Through the case study, the quality characteristics of air-conditioning product and service needed to be improved immediately are Green product (Q3) and Repair service (Q10), and the Price (Q11) and Serviceability (Q2) could be kept or enhanced to win the market competitive advantages.

Originality/value

This study developed a modified IPA to help organization identifying key quality characteristics of product and service, and choosing its improvement strategies to win the market competitive advantages effectively.

Details

The TQM Journal, vol. 28 no. 2
Type: Research Article
DOI: https://doi.org/10.1108/TQM-04-2014-0039
ISSN: 1754-2731

Keywords

  • Continuous improvement
  • Importance-performance analysis
  • Customer satisfaction
  • Comptetitive strategy
  • Mahalanobis Distance
  • Multiple regression analysis

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Article
Publication date: 1 April 2001

Investment management education: Is there a gap between the perceptions of academics and of practitioners?

H.P. Wolmarans

In recent years, investment management education has become increasingly relevant. As a result of this development, it is essential that various role players should be…

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Abstract

In recent years, investment management education has become increasingly relevant. As a result of this development, it is essential that various role players should be consulted to ensure that investment management is taught in line with practitioners’ requirements. The South African Qualifications Authority also specifies that educators and practitioners should collaborate to maintain relevance in all fields of education. The importance of various areas in investment management was investigated. This article compares the ranking of these areas in terms of their importance as perceived by academics and practitioners. The study being reported also aimed to determine whether gaps exist between the areas that academics regard to be important and the areas that practitioners regard as such. Areas that are generally regarded to be most important include asset allocation, fundamental analysis and the measurement of risk and return. Areas that are regarded to be least important include arts, antiques and other hard assets; rights and capitalisation issues; and real estate. Areas in need of research include the measurement of risk and return; asset allocation; derivatives; and global markets and instruments. The findings of this study could have a significant impact on the provision of relevant training for South African investment specialists.

Details

Meditari Accountancy Research, vol. 9 no. 1
Type: Research Article
DOI: https://doi.org/10.1108/1022252920010019
ISSN: 1022-2529

Keywords

  • Investment management education
  • SAQA requirements
  • Relevant areas in investment management

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Article
Publication date: 13 May 2019

Processing windows for Ti-6Al-4V fabricated by selective electron beam melting with improved beam focus and different scan line spacings

Christoph R. Pobel, Fuad Osmanlic, Matthias A. Lodes, Sebastian Wachter and Carolin Körner

Selective electron beam melting (SEBM) is a highly versatile powder bed fusion additive manufacturing method. SEBM is characterized by high energy densities which can be…

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Abstract

Purpose

Selective electron beam melting (SEBM) is a highly versatile powder bed fusion additive manufacturing method. SEBM is characterized by high energy densities which can be applied with nearly inertia free beam deflection at high speeds (<8.000 m/s). This paper aims to determine processing maps for Ti-6Al-4V on an Arcam Q10 machine with LaB6 cathode design.

Design/methodology/approach

Scan line spacings of 100, 50 and 20 µm in a broad parameter range, focusing on high deflection and build speeds are investigated.

Findings

There are broad processing windows for dense parts without surface flaws for all scan line spacings which are defined by the total energy input and the area melting velocity.

Originality/value

The differences and limitations are discussed taking into account the beam properties at high beam energy and velocity as well as evaporation related loss of alloying components.

Details

Rapid Prototyping Journal, vol. 25 no. 4
Type: Research Article
DOI: https://doi.org/10.1108/RPJ-04-2018-0084
ISSN: 1355-2546

Keywords

  • Research
  • Rapid prototyping
  • CAD
  • Titanium
  • Metals
  • Selective electron beam melting

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Article
Publication date: 7 December 2020

The capitalization of spatial healthcare accessibility into house prices in Taiwan: an application of spatial quantile regression

Ti-Ching Peng

Population ageing is fast becoming a major social concern across the globe. This ageing trend unavoidably fuels elders’ demand for healthcare services. As the main users…

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Abstract

Purpose

Population ageing is fast becoming a major social concern across the globe. This ageing trend unavoidably fuels elders’ demand for healthcare services. As the main users of health care service, whether the healthcare is geographically approachable in local areas is more imperative to senior residents with restricted mobility. This paper proposes to examine the effect of elders’ healthcare accessibility on property prices of Taipei Metropolis, Taiwan.

Design/methodology/approach

Luo and Qi’s (2009) enhanced two-step floating catchment area method – taking both healthcare demand and supply into account – was used to measure three types of healthcare services: “physician-to-elder ratio”, “hospital bed-to-elder ratio” and “ambulance-to-elder ratio”. Spatial quantile regression (SQR) model was then used to examine the spatial effect of healthcare accessibility on different property price ranges.

Findings

The “physician-to-elder ratio” and “hospital bed-to-elder ratio” demonstrated expected consistent positive effects across all quantiles of property prices (p < 0.01) in SQR, and its effects aggravated as the quantiles of property prices rose. The “ambulance-to-elder ratio” demonstrated a non-linear influence on property prices (i.e. a negative effect on lowest quantile prices but a positive on higher quantile prices) possibly due to the semi-obnoxious characteristic of the ambulance. That is, residents living in lower priced neighbourhoods may dislike ambulances’ annoying sound of sirens (i.e. ambulances’ disamenity), while residents living in higher valued neighbourhoods may on the contrary appreciate ambulances’ healthcare services (i.e. amenity).

Practical implications

These findings are expected to offer some insights for government’s policies in providing elders in their later years with good residential quality and easy access to healthcare resource.

Originality/value

This paper is one of the few studies that consider the capitalization of the spatial healthcare accessibility to elders into property prices. In this ageing trend across the globe, although all the accessibility to medical resources should be equally critical, the application of spatial quantile regression revealed residents’ inconsistent tendency against semi-obnoxious ambulances. It provides a different perspective in defining the importance of healthcare accessibility in neighbourhoods.

Details

International Journal of Housing Markets and Analysis, vol. ahead-of-print no. ahead-of-print
Type: Research Article
DOI: https://doi.org/10.1108/IJHMA-06-2020-0076
ISSN: 1753-8270

Keywords

  • Taiwan
  • Property prices
  • Elders
  • E2SFCA method
  • Health accessibility
  • Spatial quantile analysis

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Article
Publication date: 25 September 2020

About sad legacies: a study of the intergenerational occupational legacy in Brazil

Magno Rogério Gomes, Marina Silva da Cunha, Solange de Cássia Inforzato de Souza and Paulo Jorge Reis Mourão

This article aims to analyze the workers' probabilities of following their parents’ occupational legacy and whether these individuals are paid differently compared to…

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Abstract

Purpose

This article aims to analyze the workers' probabilities of following their parents’ occupational legacy and whether these individuals are paid differently compared to those who opted for occupations different from their parents, in Brazil.

Design/methodology/approach

To that end, the occupational legacy probability equation was estimated as the quantile wage equations with sample selection bias correction and the wage decomposition for Brazil from the microdata of the National Household Sample Survey (PNAD) of 2014. It was found that families have a strong influence on the process of choosing the careers of their children. The average probability of a young person following the occupational legacy of their parents was 41.63%. This percentage is different when analyzing different groups of individuals, such as being male or female, being in a traditional or single parent family, being in an income household lower or higher per capita.

Findings

The results also confirm the hypothesis that workers who tend to follow the occupational legacy have lower wages than individuals who choose other occupations and that this may cause a “poverty trap” since the lower the salary quantile, the stronger the “trap” as economically disadvantaged young people tend to follow in their parents' footsteps and to contribute to family income they face a tradeoff, opt between work or study, which ends up disrupting their education and forcing young people to entering the job market early, performing secondary occupations with lower income and arduous work, generating a “vicious cycle of poverty”.

Research limitations/implications

Given the database, we are comprised to its most recent version.

Practical implications

This is the first work on Latin American problem of occupational legacy.

Originality/value

This is the first work on Latin American problem of occupational legacy.

Details

International Journal of Manpower, vol. ahead-of-print no. ahead-of-print
Type: Research Article
DOI: https://doi.org/10.1108/IJM-04-2020-0156
ISSN: 0143-7720

Keywords

  • Occupational influence
  • Occupational choice
  • Quantile regressions
  • Oaxaca RIF

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Book part
Publication date: 27 August 2014

Altruism, Efficiency, and Health in the Family

Mark Dickie and Matthew J. Salois

The chapter investigates: (1) Do married parents efficiently allocate time to children’s health care? (2) Are parents willing to sacrifice consumption for health…

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Abstract

Purpose

The chapter investigates: (1) Do married parents efficiently allocate time to children’s health care? (2) Are parents willing to sacrifice consumption for health improvements at an equal rate for all family members? (3) How does family structure affect health trade-offs parents make? (4) Are parental choices consistent with maximization of a single utility function?

Methodology

A model is specified focusing on how parents allocate resources between consumption and goods that relieve acute illnesses for family members. Equivalent surplus functions measuring parental willingness to pay to relieve acute illnesses are estimated using data from a stated-preference survey.

Findings

Results provide limited support for the prediction that married parents allocate time to child health care according to comparative advantage. Valuations of avoided illness vary between family members and are inconsistent with the hypothesis that fathers’ and mothers’ choices reflect a common utility function.

Research implications

Prior research on children’s health valuation has relied on a unitary framework that is rejected here. Valuation researchers have focused on allocation of resources between parents and children while ignoring allocation of resources among children, whereas results suggest significant heterogeneity in valuation of health of different types of children and of children in different types of households.

Social implications

Results may provide a justification on efficiency grounds for policies to provide special protection for children’s health and suggest that benefit–cost analyses of policies affecting health should include separate estimates of the benefits of health improvements for children and adults.

Details

Preference Measurement in Health
Type: Book
DOI: https://doi.org/10.1108/S0731-219920140000024000
ISBN: 978-1-78441-029-2

Keywords

  • Children’s health
  • valuation
  • altruism
  • unitary model
  • efficiency

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Book part
Publication date: 18 July 2016

Forecasting Pain and Discomfort for Canines with Disease for Establishing Appropriate Medication Levels

Virginia M. Miori, Zhenpeng Miao and Yingdao Qu

This is the third in a series of papers aimed at providing models effective in predicting the degree of pain and discomfort in canines. The first two papers provided…

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Abstract

This is the third in a series of papers aimed at providing models effective in predicting the degree of pain and discomfort in canines. The first two papers provided benchmarking and examination of dogs suffering from osteoarthritis (OA). In this chapter, we extend the study to include dogs suffering from OA, sarcoma, and oral mucositis (a side effect of chemotherapy and radiation treatments). The R programming language and SAS JMP are used to clean data, generate ANOVA, LSR regression, decision tree, and nominal logistic regression models to predict changes in activity levels associated with the progression of arthritis. The predictive models provide a diagnostic basis for determining the degree of disease in a dog (based on demographics and activity levels) and provide forecasts that assist in establishing appropriate medication dosages for suffering dogs.

Details

Advances in Business and Management Forecasting
Type: Book
DOI: https://doi.org/10.1108/S1477-407020160000011005
ISBN: 978-1-78635-534-8

Keywords

  • Predictive modeling
  • SLR regression
  • ANOVA
  • decision trees
  • logistic regression

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Article
Publication date: 7 May 2019

Accruals quality and the cost of debt: the European evidence

Yasser Eliwa, Andros Gregoriou and Audrey Paterson

This paper aims to investigate the empirical relationship between the cost of debt (CoD) and accruals quality (AQ) of European listed firms during the period of 2005 to…

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Abstract

Purpose

This paper aims to investigate the empirical relationship between the cost of debt (CoD) and accruals quality (AQ) of European listed firms during the period of 2005 to 2014. Also, it aims to test the impact of the interrelationship between the financial crisis (2008-2009) and AQ on CoD. Finally, we decompose AQ into two components; the innate (InnateAQ) and discretionary components (DiscAQ); and test their relationships with CoD.

Design/methodology/approach

To empirically examine the relationship between AQ and CoD, a sample including 15 member states of the EU is constructed. AQ proxy is based on the McNichols (2002) modification of Dechow and Dichev (2002) model. A univariate analysis and a multivariate analysis are conducted to examine the relationship between AQ and CoD after controlling for firm characteristics and institutional variables.

Findings

We find a significant negative association between AQ and CoD in a vast proportion of the 15 countries under review. Also, the results indicate that during the crisis period, creditors pay relatively more attention to the quality of accounting information than during the pre-crisis period when they determine CoD of firms. Moreover, we report a link between the magnitude of this relationship and national characteristics and provide evidence of the significant effects of national characteristics and market forces on CoD. Finally, we find that InnateAQ drives the relationship with CoD.

Practical implications

This paper provides up-to-date evidence on the economic consequences of AQ and IFRS in the capital market. The results should, therefore, be of interest to managers, creditors, regulators and standard-setters.

Originality/value

To the best of the authors’ knowledge, this is the first paper to investigate the effects of AQ on CoD for European listed firms. Also, it examines the impact of financial crisis on the association between AQ and CoD.

Details

International Journal of Accounting & Information Management, vol. 27 no. 2
Type: Research Article
DOI: https://doi.org/10.1108/IJAIM-01-2018-0008
ISSN: 1834-7649

Keywords

  • EU
  • IFRS
  • Earnings quality
  • Accruals quality
  • The cost of debt

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