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1 – 5 of 5Biodegradable polymers are widely used in personalized medical devices or scaffolds for tissue engineering. The manufacturing process should be finished with sterilization…
Abstract
Purpose
Biodegradable polymers are widely used in personalized medical devices or scaffolds for tissue engineering. The manufacturing process should be finished with sterilization procedure. However, it is not clear how the different sterilization methods have an impact on the mechanical strength of the three-dimensional (3D)-printed parts, such as bone models or personalized mechanical devices. This paper aims to present the results of mechanical testing of polylactide-based bone models before and after sterilization.
Design/methodology/approach
Polylactide specimens prepared in fused filament fabrication technology were sterilized with different sterilization methods: ultraviolet (UV) and ethylene oxide. Mechanical properties were determined by testing tensile strength, Young’s modulus and toughness.
Findings
The tensile strength of material after sterilization was significantly higher after ethylene oxide sterilization compared to the UV sterilization, but in both sterilization methods, the specimens characterized lower tensile strength and Young’s modulus when compared to the control. In comparison of toughness results, there was no statistically significant differences. The findings are particularly significant in the perspective of using individual implants, bone grafts and dental guides.
Originality/value
Although fused filament fabrication (FFF) 3D printing devices equipped with UV light sterilization options are available, experimental results of the effect of selected sterilization methods on the mechanical strength of additively manufactured parts have not been described. This paper completes the present state of the art on the problem of sterilization of FFF parts from biodegradable materials.
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Sara Candidori, Serena Graziosi, Paola Russo, Kasra Osouli, Francesco De Gaetano, Alberto Antonio Zanini and Maria Laura Costantino
The purpose of this study is to describe the design and validation of a three-dimensional (3D)-printed phantom of a uterus to support the development of uterine balloon tamponade…
Abstract
Purpose
The purpose of this study is to describe the design and validation of a three-dimensional (3D)-printed phantom of a uterus to support the development of uterine balloon tamponade devices conceived to stop post-partum haemorrhages (PPHs).
Design/methodology/approach
The phantom 3D model is generated by analysing the main requirements for validating uterine balloon tamponade devices. A modular approach is implemented to guarantee that the phantom allows testing these devices under multiple working conditions. Once finalised the design, the phantom effectiveness is validated experimentally.
Findings
The modular phantom allows performing the required measurements for testing the performance of devices designed to stop PPH.
Social implications
PPH is the leading obstetric cause of maternal death worldwide, mainly in low- and middle-income countries. The proposed phantom could speed up and optimise the design and validation of devices for PPH treatment, reducing the maternal mortality ratio.
Originality/value
To the best of the authors’ knowledge, the 3D-printed phantom represents the first example of a modular, flexible and transparent uterus model. It can be used to validate and perform usability tests of medical devices.
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Christian Mauricio Cobos, Octavio Fenollar, Juan López Martinez, Santiago Ferrandiz and Luis Garzón
This paper aims to describe the influence of maleinized linseed oil (MLO), when used as a lubricant, on the thermal and rheological properties of PLA/MWCNTs (polylactic…
Abstract
Purpose
This paper aims to describe the influence of maleinized linseed oil (MLO), when used as a lubricant, on the thermal and rheological properties of PLA/MWCNTs (polylactic acid/multi-walled carbon nanotubes) and PLA/HNT (halloysite nanotubes) nanocomposites, as a reference for application in 3D printing processes.
Design/methodology/approach
Nanocomposites were obtained by melting in a twin-screw extruder, mixing PLA with MWCNTs and HNTs in different percentages of 0.5, 0.75 and 1 Wt.% for subsequent mixing by the same process with 5 phr MLO, for application in additive manufacturing, as analyzed by means of differential scanning calorimetry (DSC), capillary rheometry, melt flow rate (MFL) and field emission scanning electron microscopy (FESEM).
Findings
The results obtained for thermal characterization by using DSC indicate the non-variation of glass transition temperature Tg = 62 ± 2°C and a melting temperature (Tm) around 170°C. Crystallization temperature dropped by approximately 12°C, which should be kept in mind during the transformation processes. The values obtained by capillary rheometry indicate that the material’s viscosity is reduced by the influence of the MLO plasticizer’s lubricant effect on the PLA’s molecular structure. The melt flow index values confirm a rise of approximately 46% in the flow index and back up the capillary rheometry results. The values obtained were as follows: PLA/0.5 Wt.% MWCNT/MLO 5 phr 54.07, PLA/0.75 Wt.% MWCNT/MLO 5 phr 53.46, PLA/1 Wt.% MWCNT/MLO 5 phr 51.84y PLA/0.5 Wt.% HNT/MLO 5 phr 61.8, PLA/0.75 Wt.% HNT/MLO 5 phr 68.3 and PLA/1 Wt.% HNT/MLO 5 phr 71.2 g/10 min. Apart from the nanocharge distribution, the information obtained from the FESEM shows the existence of a cluster, which could have been avoided by more energetic stirring during the nanocompound manufacturing process.
Social implications
This paper presents an analysis of the insertion of plasticizer in nanocomposites for the application in additive manufacturing processes in fusion deposition modelling (FDM) system.
Originality/value
This is a novel original research work.
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