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Article

R. Craig Lefebvre, Lauren McCormack, Olivia Taylor, Carla Bann and Paula Rausch

The aim of this paper is to enhance the effectiveness of pharmacovigilance programs that provide information about medical products to benefit consumers, aid health care…

Abstract

Purpose

The aim of this paper is to enhance the effectiveness of pharmacovigilance programs that provide information about medical products to benefit consumers, aid health care professional’s decision-making and improve community health. This research sought to determine whether distinct segments of consumers can be identified for prescription drug safety social marketing and communication activities and if these segments would respond differently to information about prescription drug products.

Design/methodology/approach

Theories of risk information-seeking behavior were used to develop questions for respondents in an online survey panel. Latent class analyses identified clusters that were similar in their ability to accurately interpret risks and benefits, preferred sources of health information, medication use and other related factors. Multinomial logistic regression models identified demographic and psychographic differences across the segments. Logistic and linear regression models were then used to compare each segment’s responses to a specific drug safety information product.

Findings

The 1,244 respondents were clustered into four segments: not engaged (12 per cent), low-involvement users (29 per cent), careful users (50 per cent) and social information seekers (9 per cent). These segments were distinguished by perceived seeking control, self-appraisal of skill, information insufficiency, self-efficacy, information competency and health literacy. Sources of health information and health-seeking behaviors were also different across the four segments. Significant differences were found among the segments in their comprehension and perceived utility of the content and their intentions to take relevant actions.

Practical implications

From an array of potential behavioral influences, adults can be segmented by risk information-seeking constructs and related behaviors. These segments respond differently to drug safety information. Use of the personas developed in this work can help pharmacovigilance programs around the world develop more relevant and tailored social marketing products, services and content.

Originality/value

A social marketing approach using empirically tested theoretical constructs can be useful for drug safety or pharmacovigilance programs. The results were used to create personas that quickly convey relevant information to drug safety program managers and staff.

Details

Journal of Social Marketing, vol. 6 no. 4
Type: Research Article
ISSN: 2042-6763

Keywords

Content available

Abstract

Details

Benchmarking: An International Journal, vol. 12 no. 1
Type: Research Article
ISSN: 1463-5771

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Article

Wei Shang, Hsinchun Chen and Christine Livoti

The purpose of this paper is to propose a framework to detect adverse drug reactions (ADRs) using internet user search data, so that ADR events can be identified early…

Abstract

Purpose

The purpose of this paper is to propose a framework to detect adverse drug reactions (ADRs) using internet user search data, so that ADR events can be identified early. Empirical investigation of Avandia, a type II diabetes treatment, is conducted to illustrate how to implement the proposed framework.

Design/methodology/approach

Typical ADR identification measures and time series processing techniques are used in the proposed framework. Google Trends Data are employed to represent user searches. The baseline model is a disproportionality analysis using official drug reaction reporting data from the US Food and Drug Administration’s Adverse Event Reporting System.

Findings

Results show that Google Trends series of Avandia side effects search reveal a significant early warning signal for the side effect emergence of Avandia. The proposed approach of using user search data to detect ADRs is proved to have a longer leading time than traditional drug reaction discovery methods. Three more drugs with known adverse reactions are investigated using the selected approach, and two are successfully identified.

Research limitations/implications

Validation of Google Trends data’s representativeness of user search is yet to be explored. In future research, user search in other search engines and in healthcare web forums can be incorporated to obtain a more comprehensive ADR early warning mechanism.

Practical implications

Using internet data in drug safety management with a proper early warning mechanism may serve as an earlier signal than traditional drug adverse reaction. This has great potential in public health emergency management.

Originality/value

The research work proposes a novel framework of using user search data in ADR identification. User search is a voluntary drug adverse reaction exploration behavior. Furthermore, user search data series are more concise and accurate than text mining in forums. The proposed methods as well as the empirical results will shed some light on incorporating user search data as a new source in pharmacovigilance.

Details

Online Information Review, vol. 41 no. 4
Type: Research Article
ISSN: 1468-4527

Keywords

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Article

Xieling Chen, Shan Wang, Yong Tang and Tianyong Hao

The purpose of this paper is to explore the research status and development trend of the field of event detection in social media (ED in SM) through a bibliometric…

Abstract

Purpose

The purpose of this paper is to explore the research status and development trend of the field of event detection in social media (ED in SM) through a bibliometric analysis of academic publications.

Design/methodology/approach

First, publication distributions are analyzed including the trends of publications and citations, subject distribution, predominant journals, affiliations, authors, etc. Second, an indicator of collaboration degree is used to measure scientific connective relations from different perspectives. A network analysis method is then applied to reveal scientific collaboration relations. Furthermore, based on keyword co-occurrence analysis, major research themes and their evolutions throughout time span are discovered. Finally, a network analysis method is applied to visualize the analysis results.

Findings

The area of ED in SM has received increasing attention and interest in academia with Computer Science and Engineering as two major research subjects. The USA and China contribute the most to the area development. Affiliations and authors tend to collaborate more with those within the same country. Among the 14 identified research themes, newly emerged themes such as Pharmacovigilance event detection are discovered.

Originality/value

This study is the first to comprehensively illustrate the research status of ED in SM by conducting a bibliometric analysis. Up-to-date findings are reported, which can help relevant researchers understand the research trend, seek scientific collaborators and optimize research topic choices.

Details

Online Information Review, vol. 43 no. 1
Type: Research Article
ISSN: 1468-4527

Keywords

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Article

Elaine Aparecida Regiani de Campos, Istefani Carisio de Paula, Regina Negri Pagani and Patricia Guarnieri

The aim of this paper is to develop a systematic literature review (SLR) aiming to identify reverse logistics (RL) concepts and practices applied to the end-of-life (EOL…

Abstract

Purpose

The aim of this paper is to develop a systematic literature review (SLR) aiming to identify reverse logistics (RL) concepts and practices applied to the end-of-life (EOL) and end-of-use (EOU) of pharmaceuticals and to identify and synthesize, through bibliometric indicators, research opportunities on RL, considering the analysis of publications in the periodical Supply Chain Management: An International Journal (SCMij).

Design/methodology/approach

The SLR followed two steps, namely, search for articles on the subject and content analysis of selected material and bibliometric analysis of publications using VOSviewer®.

Findings

The SLR allowed the compilation of evidences regarding pharmaceutical RL in the groups: environmental risk, the RL evolution and regulatory and stakeholder’s educational perspective. Despite the timid specific literature on pharmaceutical RL, it was also possible to point out research gaps and opportunities. Pharmaceutical RL seems to be influenced by studies from traditional RL including mathematical modeling, managerial strategies and technologies but prescind of a systemic solution. Besides reducing environmental impact, the motivation to implement pharmaceutical RL resides in its potential for revenue. Considering integrated logistics as a trend and an emerging issue, RL for the pharmaceutical industry needs to be addressed more thorough and broadly.

Research limitations/implications

The limited number of papers returned in this SLR of pharmaceutical RL impaired the bibliometric analysis of them, leading to the inclusion of papers on general RL.

Originality/value

This study provides an overview of the evolution of RL in the pharmaceutical industry, it also clarifies concepts and EOL/EOU practices, particularly directed to the pharmaceutical industry RL.

Details

Supply Chain Management: An International Journal, vol. 22 no. 4
Type: Research Article
ISSN: 1359-8546

Keywords

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Article

Fatema AlZahra AlHusaini and Muneer Mohammed Saeed Al Mubarak

The purpose of this paper is to contribute to the literature by assessing factors that typically engender adverse drug reactions (ADRs) jeopardizing medical safety. These…

Abstract

Purpose

The purpose of this paper is to contribute to the literature by assessing factors that typically engender adverse drug reactions (ADRs) jeopardizing medical safety. These factors are population knowledge, clarity in disclosure of the risks inhering ADRs and ADRs incidence. It seeks to minimize negative effect by early identification of drug reactions.

Design/methodology/approach

On the one hand, the study employs a model that shows relationships between various factors, and on the other hand, ADRs medical safety in the public healthcare sector.

Findings

Clarity of consultancy services in public healthcare significantly impact ADR medical safety. Population and healthcare provider education on ADRs medical safety are necessities. Implementation of an ADR reporting system in every healthcare institute is essential. This helps service providers to give a clear and accurate information to patients. It also makes patients more aware of consequences of ADRs.

Research limitations/implications

Time, place and sampling method are found to be the main study limitations. Researchers should take into their consideration the significant relationships between the factors and ADRs medical safety to improve level of awareness in the healthcare public sector.

Practical implications

Ways to improve ADR medical safety in healthcare sector are underscored. Healthcare service providers and professionals need to take into account the stipulated study factors in order to improve medical safety and reduce unnecessary medical costs.

Originality/value

Very few studies have been conducted on this topic; most of those that have been conducted were undertaken in western countries. This study assesses the level of healthcare safety in the country and suggests mechanisms to elevate that level.

Details

International Journal of Health Care Quality Assurance, vol. 31 no. 6
Type: Research Article
ISSN: 0952-6862

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Article

Marie Claire Van Hout

The misuse of pharmaceutical opioid analgesics is identified as a global public health concern. Codeine represents an interesting quandary in terms of its regulated…

Abstract

Purpose

The misuse of pharmaceutical opioid analgesics is identified as a global public health concern. Codeine represents an interesting quandary in terms of its regulated status, with individuals varying in their metabolism of codeine, estimation of safe dosages, risk of adverse health consequences and abuse potential. Efforts to quantify and address hidden non-compliant medical codeine use, overuse and intentional misuse is compromised by availability to the public in prescribed and over the counter forms. The paper aims to discuss these issues.

Design/methodology/approach

A review of literature on codeine use, misuse and dependence, and associated innovative medical and pharmacy interventions is presented, and was conducted as part of a larger scoping review on codeine.

Findings

The review highlights the complexities associated with monitoring public health awareness of codeine's abuse potential, and customer/patients trends in non-compliant codeine use for therapeutic and recreational purposes. Aberrant codeine behaviours centre on visiting multiple doctors for prescriptions, repeated lost or stolen prescriptions, forging prescriptions and use of multiple pharmacies. Innovations to monitor misuse of codeine include national prescription databases and recent developments in real-time monitoring of dispensing activity.

Practical implications

Further development of real-time monitoring processes with process evaluation is advised.

Originality/value

This viewpoint is intended to demonstrate how efforts to quantify and address codeine use are compromised by its availability. It intends to encourage further policy and practitioner dialogue on how to monitor, support and intervene with consumers misusing codeine.

Details

Drugs and Alcohol Today, vol. 14 no. 4
Type: Research Article
ISSN: 1745-9265

Keywords

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Article

Margaret Armstrong, Guillaume Cornut, Stéphane Delacôte, Marc Lenglet, Yuval Millo, Fabian Muniesa, Alexandre Pointier and Yamina Tadjeddine

The purpose of this paper is to highlight the potentials offered by New Product Committees for the development of responsible innovation in the financial services…

Abstract

Purpose

The purpose of this paper is to highlight the potentials offered by New Product Committees for the development of responsible innovation in the financial services industry; and to provide grounds for policy recommendations.

Design/methodology/approach

The paper takes the form of collective, interdisciplinary reflection and experience within the industry.

Findings

New Product Committees can serve a practical approach to responsible innovation in finance.

Originality/value

The paper fills a gap in the empirical consideration of New Product Committees in the financial services industry and proposes original directions for policy orientations within organizations and at a regulatory level.

Details

Journal of Financial Regulation and Compliance, vol. 20 no. 2
Type: Research Article
ISSN: 1358-1988

Keywords

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Article

Marjan Dzeparoski and Suzana Trajkovic-Jolevska

The purpose of this paper is to show that advertising as part of product promotion is in strict correlation with the specific regulation of each product category, food…

Abstract

Purpose

The purpose of this paper is to show that advertising as part of product promotion is in strict correlation with the specific regulation of each product category, food supplements and herbal/over-the-counter medicines. Main contributions of the paper are two-fold. First, it demonstrates that there are products when certain botanical is registered according to legislation as herbal medicine, but at the same time it can be found in sales as food supplement. This can happen within the same country, but it is more frequent within different countries. Second, the possibility for regulation harmonization is discussed.

Design/methodology/approach

In this paper, a comparative analysis of regulation for concerned products in European Union and countries of interest is made. In two case studies, a comparative analysis of marketing of the products in Macedonia and Serbia is made.

Findings

Food supplements are subject to more liberal regulation in comparison with herbal/over-the-counter medicines, but should not be attributed indications and properties that they do not possess. Regulation is stricter and more complex for over-the-counter medicines as a separate class of medicines, these must be correlated with registered properties and indications and are subject to approval by regulatory bodies (print media: advertisement in newspaper/magazine, poster, brochure, flyer, banner and billboard and electronic media: TV spot, radio advertising and internet advertisement).

Research limitations/implications

Countries of interest: EU, Macedonia, Serbia, Montenegro, Albania, Kosovo, Bosnia and Herzegovina.

Practical implications

The paper will contribute toward the creation of promotional and marketing steps in placement of these products on the market in countries of interest, based on regulation of the product category.

Social implications

The discussed opportunities for harmonization are applicable and realistic and can positively contribute for better flow and placement of food supplements and herbal/over-the-counter medicines in different countries. The results of the case studies can also be used for regulatory activities and preparation of marketing materials for other products on other markets of interest with same or similar regulation.

Originality/value

For the first time, a comparative analysis of regulation is made for concerned products in countries of interest. Possibility for regulation harmonization is discussed.

Details

International Journal of Pharmaceutical and Healthcare Marketing, vol. 12 no. 1
Type: Research Article
ISSN: 1750-6123

Keywords

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Article

Liliana Alexandra Monteiro Guerra and Paula Façanha da Cruz Fresco

The primary purpose of this paper is to collect reliable information to characterize the pharmacy services in Portuguese prisons. The secondary purpose is to develop a set…

Abstract

Purpose

The primary purpose of this paper is to collect reliable information to characterize the pharmacy services in Portuguese prisons. The secondary purpose is to develop a set of suggestions for improving these services and, therefore, improve the health services provided to the inmate population.

Design/methodology/approach

A three pages survey was developed that included questions covering the characterization of prison health teams, pharmacy services and pharmacy activities. This survey was sent to all Portuguese prisons, with capacity higher than 50 prisoners. The response rate was of 87.5 per cent.

Findings

It was found that only 6.1 per cent of prisons had pharmacists and that in 63 per cent the guards still participated in pharmacy activities. There were not Pharmacy and Therapeutics Committees in 94 per cent of prisons and 94.4 per cent did not present adequate storage conditions for drugs. Only 51.7 per cent of prisons had computers in the pharmacy and only 3.4 per cent had access to the internet. This study found that there is a gap between public and prison pharmacy services, since most prison pharmacies in Portugal are solely locals of storage and distribution of drugs, with no effective management nor promotion of drug rational use.

Originality/value

This paper is the first study about pharmacy services in Portuguese prisons. The information collected could be very useful to improve the Portuguese prison pharmacy services provided to prisoners.

Details

International Journal of Prisoner Health, vol. 9 no. 4
Type: Research Article
ISSN: 1744-9200

Keywords

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