Search results

1 – 10 of over 1000
Article
Publication date: 27 February 2007

Pascal Bador, Chérifa Boukacem‐Zeghmouri, Thierry Lafouge, Hélène Prost and Joachim Schöpfel

The article aims to investigate the correlation between citations and the document supply of print serials.

Abstract

Purpose

The article aims to investigate the correlation between citations and the document supply of print serials.

Design/methodology/approach

The study is based on data from INIST‐CNRS for document supply requests and from ISI for citations from 89 serials with JCR impact factors in pharmacology. Data were collected from 1992 to 2004.

Findings

The results distinguish four groups of serials with different relationships between document supply requests and citations. The characteristics of the serials of the four groups are described (year of creation, price, etc.). The evolution of the correlation between document supply and citations is analysed.

Originality/value

This is the second of three articles on a longitudinal study over 13 years on different aspects of the relationship between document supply and impact factor (citations) in pharmacology, a scientific domain with a high use of scientific information.

Details

Interlending & Document Supply, vol. 35 no. 1
Type: Research Article
ISSN: 0264-1615

Keywords

Article
Publication date: 15 December 2023

Stanimir Čekerinac, Ana Starčević, Miloš Basailović, Dušan Sekulić and Nevena Divac

Prison settings have limited resources, and it is of particular interest to analyze which antipsychotics are commonly prescribed in these conditions and to determine the…

Abstract

Purpose

Prison settings have limited resources, and it is of particular interest to analyze which antipsychotics are commonly prescribed in these conditions and to determine the prevalence of the adverse effects.

Design/methodology/approach

A cross-sectional, epidemiological survey was used to measure the prevalence of antipsychotic prescribing among adult prisoners in Sremska Mitrovica Prison in 2020.

Findings

The prevalence of antipsychotic use was 7.58%. The most commonly prescribed antipsychotic was clozapine (45.36%), but also olanzapine, haloperidol and risperidone were prescribed. The incidence of extrapyramidal adverse effects was nonexistent and the metabolic parameters did not differ between participants using metabolic syndrome–inducing antipsychotics and those who were prescribed metabolically inert medications. The prescribed doses were lower compared with the recommended.

Research limitations/implications

This research includes certain points that should be cautiously considered. First, the data were cross-sectional and the findings did not provide causal interpretations. Second, the data are from a single penitentiary institution, albeit the largest in the country; however, that may affect the generalizability of the findings. Third, because the included subjects were not hospitalized, some laboratory analyses were not available, according to the local regulations, and thus the prevalence of metabolic syndrome could not be precisely determined.

Practical implications

The prevalence of the antipsychotic use in prison environment is significantly higher than in general population. The most frequently prescribed antipsychotics are clozapine and olanzapine. The prevalence of adverse effects is rare, however, that is possibly due to low doses of the prescribed antipsychotics. The list of therapeutic options available to the incarcerated persons in this facility is also limited. The list of available antipsychotics does not include some atypical antipsychotics with more favorable safety and tolerability profile, such as aripiprazole or cariprazine. Long-acting antipsychotic injectables were also not available to these patients. Laboratory analyses are not regularly conducted and do not include some essential parameters such as lipid status or differential blood count. Low-dose antipsychotics for behavioral symptoms appears to be well tolerated under prison conditions where adherence is assured. It is effective during the prison stay but long-term effects, especially after release from prison, had not been studied.

Social implications

This paper advocates for better quality of health care in this correctional facility: more therapeutic options and better laboratory monitoring. The authors justify the use of clozapine in this settings due its benefits in reducing violence and aggression; however, further research would be necessary to clarify does the use of clozapine in incarcerated persons cause behavioral improvements that could result in shorter incarcerations, less recidivism and better quality of life.

Originality/value

To the best of the authors’ knowledge, this is the first insight of the antipsychotic prescribing practice in Serbia. There is very limited data on prisoners’ health care, especially mental health care, in Balkan countries. The antipsychotic prescribing pattern in this sample is characterized with higher than expected clozapine use, but without expected adverse effects.

Details

International Journal of Prison Health, vol. 20 no. 1
Type: Research Article
ISSN: 2977-0254

Keywords

Article
Publication date: 20 March 2017

John Pell

125

Abstract

Details

Reference Reviews, vol. 31 no. 3
Type: Research Article
ISSN: 0950-4125

Keywords

Article
Publication date: 18 May 2015

Vigdis Boasson and Emil Boasson

The purpose of this paper is to examine the role of geographic location of research-intensive firms in the ability to generate new research and products, which consequently…

Abstract

Purpose

The purpose of this paper is to examine the role of geographic location of research-intensive firms in the ability to generate new research and products, which consequently affects firm value.

Design/methodology/approach

The authors conduct the empirical study following a three-step process. First, if pharmaceutical firms are more likely to cite the patents of other firms and other innovators that are nearby, as opposed to firms and other innovators that are far away, then location (i.e. close proximity) is likely important when it comes to the ability to learn and to use the knowledge being generated by other innovators. The authors employ a “geographic information systems” (GIS) and geo-code each pair of citing and cited patents. In addition, the authors utilize spatial statistics such as Moran’s I to analyze the spatial clustering pattern of patent citations and knowledge flows. Next, the authors measure the pharmaceutical companies’ ability to generate useful patents as a function of the amount of innovation and industrial activity that is occurring close to them. Finally, the authors test whether a firm’s location relates to its firm value. Specifically, the authors model firm value as a function of its patents quality, but the authors also allow the firm’s patents quality to be a function of its location and locational attributes. In this way, the authors establish a link between location and firm value. Using a simultaneous system of equations, the authors find that location explains patent quality, which, in turn, explains firm value. In other words, there is a positive relationship between firm value, innovation and location.

Findings

In empirical tests using pharmaceutical firms and their patents, the authors first find that firms more often cite patents of other firms that are geographically closer to them than those firms that are farther away. The authors then find that a patent’s quality is a function of the firm’s near proximity to other knowledge-intensive institutions and activities. Finally, the authors find that because patent quality is a function of a firm’s geographic location, location consequently affects firm value.

Research limitations/implications

For knowledge-intensive firms, geographic location matters. More specifically, the authors contend that research-intensive firms are better able to use and to expand on existing knowledge when they are closer to other research-intensive enterprises. The implication is that firm value maximization involves a location factor.

Practical implications

The practical implication for investors is that investors should invest in those firms that are situated in a location that is rich in geographic innovation resources because those firms are more likely to generate more and higher quality patents or innovations.

Originality/value

The study is the first to establish the linkage among spatial knowledge diffusion, geographic drivers of innovation, and market valuation of the firm. The study is unique in that the authors not only present evidence on spatial knowledge flows by geo-coding the exact longitude and latitude location coordinates of citing and cited patens, but more importantly, the authors also identify geographic drivers of innovation, and examine their impacts on citation-weighted patent counts and knowledge stock. Finally, using a series of simultaneous equations, the authors show how geographic innovation resources positively affect citation-weighted patent stock and knowledge stock and consequently affect market value of the firm. Thus, the novel approach contributes not only to the literature that measures geographic localization of knowledge flow using patent citations, but also to the literature that examines the impact of geographic sources of innovations on patent outputs and patent quality and, thus on firm value for research-intensive firms.

Details

China Finance Review International, vol. 5 no. 2
Type: Research Article
ISSN: 2044-1398

Keywords

Article
Publication date: 21 August 2007

Pascal Bador, Chérifa Boukacem‐Zeghmouri, Thierry Lafouge, Hélène Prost and Joachim Schöpfel

The article aims to investigate the customers for the document supply of print serials.

Abstract

Purpose

The article aims to investigate the customers for the document supply of print serials.

Design/methodology/approach

The study is based on data from INIST‐CNRS for document supply requests in pharmacology. Data were collected from 1998 to 2005 (10,000+ customer accounts with 4.6m orders).

Findings

The article provides information about the distribution of orders per customer type, about the geographical origin of customers, about the ordering trends among pharmaceutical customers and of pharmaceutical journals.

Originality/value

This is the last of three articles on a longitudinal study over 13 years on different aspects of the relationship between document supply and impact factor (citations) in pharmacology, a scientific domain with a high use of scientific information.

Details

Interlending & Document Supply, vol. 35 no. 3
Type: Research Article
ISSN: 0264-1615

Keywords

Article
Publication date: 1 October 2006

Chérifa Boukacem‐Zeghmouri, Pascal Bador, Thierry Lafouge, Hélène Prost and Joachim Schöpfel

The article seeks to investigate the evolution of document supply of print serials.

Abstract

Purpose

The article seeks to investigate the evolution of document supply of print serials.

Design/methodology/approach

The study is based on data from INIST‐CNRS – document supply requests and access to electronic resources – of 95 serials with JCR impact factors in pharmacology. Data were collected from 1992 to 2003.

Findings

The results distinguish four groups of serials each with a different evolution of document supply requests. Nevertheless, the overall decline from 1999 is a global phenomenon linked to growing access to online journals and there seems little likelihood of a slowdown for the next few years.

Originality/value

This is the first of three articles on a longitudinal study over 12 years on different aspects of the relationship between document supply and impact factor (citations) in pharmacology, a scientific domain with a high use of scientific information.

Details

Interlending & Document Supply, vol. 34 no. 4
Type: Research Article
ISSN: 0264-1615

Keywords

Article
Publication date: 1 July 2004

Peter Strong

121

Abstract

Details

Reference Reviews, vol. 18 no. 5
Type: Research Article
ISSN: 0950-4125

Keywords

Article
Publication date: 12 August 2014

Duccio Papanti, Laura Orsolini, Giulia Francesconi and Fabrizio Schifano

“Spice” products are synthetic cannabimimetics (SC; also called “synthetic cannabinoids”)-based designer drugs used as a legal alternative to cannabis for their very strong…

Abstract

Purpose

“Spice” products are synthetic cannabimimetics (SC; also called “synthetic cannabinoids”)-based designer drugs used as a legal alternative to cannabis for their very strong tetrahydrocannabinol (THC)-like effects. The purpose of this paper is to provide an analysis of more recent clinical and pharmacology/toxicology findings relating to SC and describe how they could impact on health, with a particular focus on mental health.

Design/methodology/approach

A systematic search and descriptive analysis of the available evidence on psychopathological issues related to misuse was performed here, whilst taking into account the Pubmed/Medline databases, a range of conference proceedings and national/international agencies’ reports.

Findings

While THC is a partial agonist, SC are full agonists on the cannabinoid receptors (CB-rs) and the administration of multiple SC can produce additive and/or synergistic agonistic interaction effects on the endocannabinoid system. These levels of strong CB-rs’ activation may be high enough to produce severe physiological and psychological disturbances. The available evidence suggests an existing relationship between SC use and psychosis (“Spiceophrenia”). The acute SC intoxication is usually characterized by tachycardia/hypertension; visual/auditory hallucinations; mydriasis; agitation/anxiety; tachypnoea; nausea/vomiting; and seizures.

Research limitations/implications

The absence of clinical trials and longitudinal studies, together with the heterogeneity of SC compounds does not facilitate a precise assessment of the health risks related to their use, with long-term effects being of particular concern.

Originality/value

Appropriate, non-judgemental, prevention campaigns with a special focus on the differences between SC and cannabis may need to be organized on a large scale. At the same time, clinicians need to be regularly updated about novel psychoactive substances, including SC, to promptly recognize signs/symptoms of intoxication.

Details

Advances in Dual Diagnosis, vol. 7 no. 3
Type: Research Article
ISSN: 1757-0972

Keywords

Article
Publication date: 1 March 1974

F.W. LANCASTER

Mailed questionnaires were used to study the use of two printed current awareness devices in specialized areas of the neurosciences, one manually prepared and the other a product…

Abstract

Mailed questionnaires were used to study the use of two printed current awareness devices in specialized areas of the neurosciences, one manually prepared and the other a product of MEDLARS. The study determined who uses each publication, how much, for what purpose, and with what degree of success. A major purpose was to discover how valuable the publications are to users and what impact they have had on their own research or professional practice as well as on their information seeking behaviour. Comparisons are made between the results for the two publications. Some conclusions are drawn on information seeking behaviour in the neuroscience community and on requirements for effective current awareness services in this field.

Details

Journal of Documentation, vol. 30 no. 3
Type: Research Article
ISSN: 0022-0418

Article
Publication date: 9 February 2010

M. Hourdakis, D. Papandreou, P. Malindretos, D. Vassilakou, N. Papastergiou, D. Tantsidis and D. Kouvelas

It is commonly asserted that a lot of people may gain about 2.5 kg of weight or more over holiday periods, however data are limited. The purpose of this paper is to assess…

Abstract

Purpose

It is commonly asserted that a lot of people may gain about 2.5 kg of weight or more over holiday periods, however data are limited. The purpose of this paper is to assess potential changes that may occur in body weight, body mass index (BMI) and waist circumference during Easter holidays.

Design/methodology/approach

A total of 138 college students participate in the study in the morning after a 12 h fasting. Body weight is assessed using an electronic scale (Seca ± 0.1 g), wearing minimal clothing. Paired t‐test is used to assess changes in body weight before and after a holiday period.

Findings

The mean (±SD) weight increases significantly during the holiday period (+1.5 ± 2.4 kg, p < 0.001) and (+1.7 ± 1.3 kg, p < 0.001) for both males and females, respectively. When subjects are classified by BMI as normal or overweight (OW)/obese, a significant 2.6 ± 3.5 kg gain is found (p < 0.05) in the OW/obese group (≥25 kg/m2). The average holiday gain is less than what is commonly asserted. This gain is not usually reversed and may contribute to the increase of body weight that frequently occurs during adulthood.

Research limitations/implications

A convenience sample (college students), rather than a population‐based sample is used; also the activity level of the subjects is not measured, which might influence the body weight gain.

Originality/value

The paper should be of value to nutritionists and clinical dietetics.

Details

Nutrition & Food Science, vol. 40 no. 1
Type: Research Article
ISSN: 0034-6659

Keywords

1 – 10 of over 1000