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The use of sequence and structure databanks is examined in relation to their application in some of the main branches of protein studies. Also the question of availability is addressed by means of presenting some information on current sequence and structure databanks. Increasingly research in molecular science requires joint access to both sequence and structure databases, and the reasons for this development, together with some of the methods for integrated access, are analysed.

Gene term variation is a shortcoming in text‐mining applications based on biomedical literature‐based knowledge discovery. The purpose of this paper is to propose a technique for normalizing gene names in biomedical literature.

Under this proposal, the normalized forms can be characterized as a unique gene symbol, defined as the official symbol or normalized name. The unification method involves five stages: collection of the gene term, using the resources provided by the Entrez Gene database; encoding of gene‐naming terms in a table or binary matrix; design of a parametrized finite‐state graph (P‐FSG); automatic generation of a dictionary; and matching based on dictionary look‐up to transform the gene mentions into the corresponding unified form.

The findings show that the approach yields a high percentage of recall. Precision is only moderately high, basically due to ambiguity problems between gene‐naming terms and words and abbreviations in general English.

The major limitation of this study is that biomedical abstracts were analyzed instead of full‐text documents. The number of under‐normalization and over‐normalization errors is reduced considerably by limiting the realm of application to biomedical abstracts in a well‐defined domain.

The system can be used for practical tasks in biomedical literature mining. Normalized gene terms can be used as input to literature‐based gene clustering algorithms, for identifying hidden gene‐to‐disease, gene‐to‐gene and gene‐to‐literature relationships.

Few systems for gene term variation handling have been developed to date. The technique described performs gene name normalization by dictionary look‐up.

A review was carried out of the ‘information landscape’ within the pharmaceuticals‐based molecular biology community, which examined the research problems requiring biological‐sequence data, important sources of information, methods of access, information‐seeking behaviour of end users and the role of libraries and information centres. This work concentrated on the practical aspects of how biological sequence information is managed and used in a research setting and was carried out as part of the MSc in Information Science at the City University. Fifteen questionnaires were sent to information scientists in the UK pharmaceutical industry and a user study was carried out amongst scientists at Celltech. Most of the important primary data are available freely or cheaply via the Internet and molecular biologists were found to be self‐reliant in their use of these resources. Currency of information was found to be very important in the research process and the issue of Internet security was taken very seriously. Most questionnaire respondents saw a productive role in the future for information workers in the field of molecular biology, citing end‐user training and data integration as possible roles, although the degree of involvement will depend on the particular mix of skills and experience that exist within an information department.

Describes both MRPII and JIT, reviews their strengths and weaknesses, and investigates their potential complementary nature. Suggests a step‐by‐step implementation of MRPII/JIT integration. Shows that several technical problems are solvable, and that MRPII and JIT are suitable in many similar environments. Analyses justification of change using current and alternative accounting methods, and studies the implications of integration for methods of performance measurement. Suggests that JIT undermines traditional management accounting methods and demands non‐financial methods such as Activity‐Based Costing (ABC). However, also suggests that integrated schemes require major organizational and political change.

Despite arguments that traditional product costing and variance analysis operate contrary to the strategic goals of advanced manufacturing practices such as just in time (JIT), total quality management (TQM), and Six Sigma, little empirical evidence exists that cost accounting practices (CAP) are changing in the era of continuous improvement and waste reduction. This research supplies some of the first evidence of what CAP are employed to support the information needs of a world-class manufacturing environment. Using survey data obtained from executives of 121 U.S. manufacturing firms, the study examines the relationship between the use of JIT, TQM, and Six Sigma with various forms of traditional and non-traditional CAP. Analysis of variance tests (ANOVA) indicate that most traditional CAP continue to be used in all manufacturing environments, but a significant portion of world-class manufacturers supplement their internal management accounting system with non-traditional management accounting techniques.

The purpose of this paper is to answer two main research questions. First, the authors ask the degree to which the UK corporate governance code has changed in response to both systemic perturbations and the subsequent enquiries established to recommend solutions to perceived shortcomings. Second, the authors ask how the solutions proposed in these landmark governance texts might be explained.

The authors take a critical discourse approach to develop and apply a discourse model of corporate governance reform. The authors draw together data on popular, corporate-political and technocratic discourses on corporate governance in the UK and analyse these data using content analysis and the historical discourse approach.

The UK corporate governance code has changed little despite periodic crises and the enquiries set up to investigate and make recommendation. Institutional stasis, the authors find, is the product of discourse capture and control by elite corporate actors aided by political allies who inhabit the same elite habitus. Review group members draw intertextually on prior technocratic discourse to create new canonical texts that bear the hallmarks of their predecessors. Light touch regulation by corporate insiders thus remains the UK approach.

This is one of the first applications of critical discourse analysis in the accounting literature and the first to have conducted a discursive analysis of corporate governance reports in the UK. The authors present an original model of discourse transitions to explain how systemic challenges are dissipated.

This study explores how a small minority of social entrepreneurs break free from third sector constraints to conceive, create and grow non-profit organisations that generate social value at scale in new and innovative ways.

Six narrative case histories of innovative social enterprises were developed based on documents and semi-structured interviews with founders and long serving executives. Data were coded “chrono-processually”, which involves locating thoughts, events and actions in distinct time periods (temporal bracketing) and identifying the processes at work in establishing new social ventures.

This study presents two core findings. First, the paper demonstrates how successful social entrepreneurs draw on their lived experiences, private and professional, in driving the development and implementation of social innovations, which are realised through application of their capabilities as analysts, strategists and resources mobilisers. These capabilities are bolstered by personal legitimacy and by their abilities as storytellers and rhetoricians. Second, the study unravels the complex processes of social entrepreneurship by revealing how sensemaking, theorising, strategizing and sensegiving underpin the core processes of problem specification, the formulation of theories of change, development of new business models and the implementation of social innovations.

The study demonstrates how social entrepreneurs use sensemaking and sensegiving strategies to understand and address complex social problems, revealing how successful social entrepreneurs devise and disseminate social innovations that substantially add value to society and bring about beneficial social change. A novel process-outcome model of social innovation is presented illustrating the interconnections between entrepreneurial cognition and strategic action.

The official history of an organization is usually found on the organization’s website and in brochures. The purpose of this paper is to explore the narrative of an institution’s official history, the autobiography, as compared to the biography constructed by researchers.

A case study was conducted on the Organization of Latin American Immigrants in Israel (OLEI), covering the entire history of the organization. Based on a longitudinal, holistic and qualitative perspective, the research methodology combines data collected from interviews, archival and digital sources. The access to these data enables researchers to explore some of the reasons and circumstance behind the construction of the official history.

The analysis of the data revealed a significant gap between the autobiography and the biography in four episodes. The common thread running through them was the creation of a narrative that reinforces and emphasizes the growth and stability of the organization, through the use of strategies such as forgetting, erasing and remythologizing. This narrative was found to have been re-constructed following a period of instability.

The originality of this study relies on the use of the terminology of autobiography and biography for the exploration of the official history of an organization. The innovative research methodology applied in this paper, which compares an organization’s biography with its autobiography, enables the exploration of different dimensions and dynamics, emphasizing the value of understanding autobiography by constructing a biography.

This study explores the politics of ideology in the process of sensegiving and sensemaking at a Japanese retailer in Hong Kong. Studies on power and politics are scarce despite key role of power and politics in understanding the factors behind the conflict between the management's policy legitimization (sensegiving) and employees' policy interpretation (sensemaking). By using the three dimensions proposed in the critical sensemaking approach (discourse, rules and contexts), this paper explores the complex mechanism of power and politics in sensemaking and sensegiving.

Using 15 months of participant observation as a salesperson, this paper discusses how the Japan-centric customer service philosophy (dominant discourse), customer service policies and practices (organizational rules) and asymmetric power structure between the Japanese global headquarters and Hong Kong subsidiaries (formative contexts) are presented and perpetuated through the sensegiving–sensemaking process.

Dominant discourse was observed in the management's sensegiving, which placed the Japanese style of customer service over others. This ethnocentric dominant discourse informed the creation of customer service policies, although the realization of the discourse was determined by the employees' conflicting interpretations of the organizational rules. As a formative context, an asymmetric power structure was present that positioned the Hong Kong subsidiary as subservient to the global headquarters in Japan. This shows that the political process of sensegiving and sensemaking deeply implicates the dominant discourse, organizational rules and power structure as central forces that determine the level of perpetuating ideology.

This research illustrates the wider implications of power and politics in sensegiving–sensemaking studies and provides a complex picture of ethnocentric management.

The purpose of this paper is to explore whether there is a link between retrospective and prospective sensemaking by analyzing metaphors of past and potential future changes.

The article draws on interview data from employees, team managers and middle managers at an IT department of a Nordic bank.

The study found that organizational members' sensemaking of changes in the past were characterized by trivializing metaphors. In contrast, future-oriented sensemaking of potential changes were characterized by emotionally charged metaphors of uncertainty, war and the End, indicating that the organizational members anticipating a gloomier future.

These findings might be limited to the organizational context of an IT department of a bank with IT professionals having an urge for control and sharing a history of a financial sector changing dramatically the last decade.

This article contributes to the emerging field of future-oriented sensemaking by showing what characterize past and future-oriented sensemaking of changes at a bank. Further, the paper contributes with an empirical study unpacking how organizational members anticipate an undesired future which might not be grounded in retrospective sensemaking.