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The purpose of this study was to examined the health effects of raw and cooked aqueous and methanol extracts of Vigna unguiculata on kidney function in Wistar rats.

Thirty-six Wistar rats (weighing 160 ± 10 g) were randomly assigned into nine (9) groups (n = 4). Group I (control): no extract. Groups II and III (aqueous extract of the cooked 350 mg/kg and 550 mg/kg). Groups IV and V (methanol extracts of cooked 350 mg/kg and 550 mg/kg). Groups VI and VII (methanol extracts of raw 350 mg/kg and 550 mg/kg). Groups VIII and IX (aqueous extract of raw 350 mg/kg and 550 mg/kg). After the seventh day of the trial, the rats were euthanized with chloroform, and blood samples were collected for biochemical analysis.

Results showed that the doses applied for cooked and raw V. unguiculata significantly (p < 0.05) enhanced kidney functions by increasing the body weight, glucose level, concentration of serum urea, creatinine, total protein, potassium and chloride in test groups compared with control. The packed cell volume and haemoglobin concentrations of raw aqueous extract at 550 mg/kg (36.5 ± 5.1; 12.3 ± 2.8) were significantly (p = 0.001) higher (29.8 ± 11.8; 10.3 ± 3.9) than the 350 mg/kg dose of the same extract, and cooked aqueous extract at 350 mg/kg dose was significantly (p = 0.001) higher (28.0 ± 10.1; 9.3 ± 3.4) than that of 550 mg/kg (25.8 ± 4.9; 8.8 ± 3.9) dose of the extracts.

The nutritional content of V. unguiculata potentially can augment the nutritional content of a diet and to a large extent, the regular consumers’ health. Essentially, V. unguiculata is composed of both macro and micronutrients capable of promoting normal kidney function.

The alternative medical practices of both Ottoman and Andalusian heritages could be shown through bloodletting and cupping therapies that have been utilized in various ancient civilizations. The current study endeavors to explore the historical implementation of bloodletting as a sustainable medical heritage by Muslim physicians in the Andalusian and Ottoman empires as a part of their surgical heritage that is documented in their manuscripts and miniatures.

The primary research materials utilized in this case study are the copy of the manuscript Al-Tasrif li-man ‘Ajiza ‘an al-Taʾlif in Berlin library and the copy of the manuscript Cerrahiye-I Ilhaniye of the National Library in Paris. The study applies an analytical comparative approach to examine the practice of bloodletting by two Muslim physicians as a part of reviving heritage usage.

The present study investigates the heritage in both periods throughout implementation of cupping therapy by Al-Zahrawi and Sabuncuoglu, while also examining the resemblances and divergences in the techniques of bloodletting as a heritage medical treatment employed by these Muslim physicians and still used in Muslim culture and could be used in medical tourism purposes.

The current study aims to investigate the understanding and implementation of heritage bloodletting and cupping therapy as a sustainable tool in surgical purposes, through an exploration of treatment methods detailed in both manuscripts. Additionally, it examines the contributions made by the two surgeons toward the development of new cups and the refinement of processes involved in bloodletting and cupping therapy. Furthermore, the study highlights the locations where cupping can be performed and differentiates between dry and wet cupping techniques, as depicted in the painted instruments documented in both manuscripts.

To study the consumption pattern, attitude and knowledge of the general population about dietary supplements (DS) in the United Arab Emirates (UAE).

A community-based cross-sectional study was conducted to collect data on knowledge, attitude and consumption pattern related to the use of DS. Participants aged = 18 years were asked to complete a self-administered online questionnaire that included demographic characteristics, health and lifestyle information, consumption patterns, attitudes and knowledge levels regarding the use of DS.

A total of 207 individuals participated in the study, and 117 (56.5%) participants reported using DS products as influenced by the pandemic of coronavirus disease 2019 (COVID-19), of which 63 (53.8%) participants had been using DS for more than one month but less than one year. The majority of the participants was females (64.7%), non-UAE nationals (60.9%) and employed (51.7%). Multivitamins (77.8%) were the most commonly used DS. Use of DS was more prevalent among older participants (n = 78 (61.9%), p = 0.006), non-UAE nationals (n = 79 (62.7%), p = 0.025) and employed (n = 69 (64.5%), p = 0.023). Improving general health (76.1%) and immune booster (47%) were the most frequently identified reasons for using DS, which is relatable to the COVID-19 pandemic. The majority of study participants (72.12%) reported knowing relatively little about the use of DS. About 154 participants (74.4%) did not know that DS products do not treat diseases.

Further studies with a larger sample size need to be conducted to examine the association between gender or chronic disease and the consumption and type of DS products used to fill the gap in the literature and overcome the limitations identified in this study.

This study highlights the need for community education programs and strategies that can raise awareness of the health benefits and risks of using DS. Further studies with a larger sample size need to be conducted to examine the association between gender or chronic disease and the consumption and type of DS products used to fill the gap in the literature and overcome the limitations identified in this study.

In the spirit of the theme of this current volume, this chapter offers a contribution to care/user-involved research in terms of a personal experience. It is argued that while recognizing how difficult it is for patients/care users to be ‘fully informed’, they should at least be ‘adequately’ informed. Full information can be confusing, daunting, anxiety-inducing and not necessarily helpful to the patient or service user. But adequate information can reduce uncertainty, return some power and sense of control to the user and consequently improve the patient experience. This experience is reflected by a former educator of health professionals who is now a full-time service user – hence the ‘expertise’ offered comes from both sides of the engagement. The focus is on problems associated with waiting for treatment.

The ketogenic diet (KD) has gained popularity due to its ability to improve type 2 diabetes, weight loss, antioxidant and anti-inflammatory activity. However, long-term use of the KD might not be safe due to its adverse effects. This study examined the effects of the KD alone or in combination with Zamzam water (holy water for Muslims) on glucose homeostasis, lipid parameters and oxidant-antioxidant variables in rats.

Based on the diet given for ten weeks, three groups of adult male Wistar rats were made (12 rats/group): (1) rats which fed on a chow diet and ordinary water, (2) rats which fed on KD and ordinary water and (3) rats which were given KD along with Zamzam. Fasting blood glucose (FBG), serum insulin, insulin resistance (HOMA-IR), LDL cholesterol, HDL cholesterol, superoxide dismutase and malondialdehyde were compared by one-way ANOVA followed by post-hoc Tukey’s HSD test among groups.

Rats which fed on KD and Zamzam water had significantly reduced FBG and LDL cholesterol compared to the rats which fed on a chow diet and ordinary water (p-values 0.001), and KD and ordinary water (p-value 0.004 and 0.006, respectively). Serum insulin, insulin resistance, HDL cholesterol, superoxide dismutase and malondialdehyde did not differ significantly.

Consumption of KD along with Zamzam for ten weeks significantly reduces FBG and LDL cholesterol. KD alone does not decrease these parameters in ten weeks duration.

Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder that significantly impacts the quality of life of affected individuals. Diet has been identified as a potential modifiable risk factor for IBS, yet its association with IBS risk in the Kurdish adult male population remains understudied. This case-control study aimed to investigate the association between the lifeline diet score (LLDS), a validated tool assessing overall diet quality and the risk of IBS in Kurdish adult men.

A total of 200 Kurdish adult men were recruited, comprising 100 IBS patients (cases) and 100 healthy controls without IBS. Medical records and interview questionnaires were used to confirm IBS diagnoses, while detailed dietary questionnaires were administered to assess participants’ dietary habits and calculate their respective LLDS scores. Logistic regression analysis was used to examine the association between LLDS and IBS risk, adjusting for potential confounding factors.

Participants with higher LLDS scores exhibited a significantly reduced risk of IBS compared to those with lower LLDS scores (OR= 0.38, 95% confidence intervals = 0.18–0.77; p <0.001). The association remained statistically significant even after controlling for potential confounders such as socioeconomic status, age, eating rate, protein, fat, physical activity and body mass index.

This case-control study demonstrates a significant inverse association between the LLDS and the risk of IBS in Kurdish adult men. Higher LLDS scores, indicative of a healthier and more balanced diet, were associated with a decreased risk of IBS. These findings highlight the potential role of dietary patterns in IBS prevention and management within the Kurdish adult male population.

This study aims to examine the blockchain landscape in supply chain management by drawing insights from academic and industry literature. It identifies the key drivers, categorizes the products involved and highlights the business values achieved by early adopters of blockchain technology within the supply chain domain. Additionally, it explores fingerprinting techniques to establish a robust connection between physical products and the blockchain ledger.

The authors combined the interpretive sensemaking systematic literature review to offer insights into how organizations interpreted their business challenges and adopted blockchain technology in their specific supply chain context; content analysis (using Leximancer automated text mining software) for concept mapping visualization, facilitating the identification of key themes, trends and relationships, and qualitative thematic analysis (NVivo) for data organization, coding and enhancing the depth and efficiency of analysis.

The findings highlight the transformative potential of blockchain technology and offer valuable insights into its implementation in optimizing supply chain operations. Furthermore, it emphasizes the importance of product provenance information to consumers, with blockchain technology offering certainty and increasing customer loyalty toward brands that prioritize transparency.

This research has several limitations that should be acknowledged. First, there is a possibility that some relevant investigations may have been missed or omitted, which could impact the findings. In addition, the limited availability of literature on blockchain adoption in supply chains may restrict the scope of the conclusions. The evolving nature of blockchain adoption in supply chains also poses a limitation. As the technology is in its infancy, the authors expect that a rapidly emerging body of literature will provide more extensive evidence-based general conclusions in the future. Another limitation is the lack of information contrasting academic and industry research, which could have provided more balanced insights into the technology’s advancement. The authors attributed this limitation to the narrow collaborations between academia and industry in the field of blockchain for supply chain management.

Practitioners recognize the potential of blockchain in addressing industry-specific challenges, such as ensuring transparency and data provenance. Understanding the benefits achieved by early adopters can serve as a starting point for companies considering blockchain adoption. Blockchain technology can verify product origin, enable truthful certifications and comply with established standards, reinforcing trust among stakeholders and customers. Thus, implementing blockchain solutions can enhance brand reputation and consumer confidence by ensuring product authenticity and quality. Based on the results, companies can align their strategies and initiatives with their needs and expectations.

In essence, the integration of blockchain technology within supply chain provenance initiatives not only influences economic aspects but also brings substantial social impacts by reinforcing consumer trust, encouraging sustainable and ethical practices, combating product counterfeiting, empowering stakeholders and contributing to a more responsible, transparent and progressive socioeconomic environment.

This study consolidates current knowledge on blockchain’s capacity and identifies the specific drivers and business values associated with early blockchain adoption in supply chain provenance. Furthermore, it underscores the critical role of product fingerprinting techniques in supporting blockchain for supply chain provenance, facilitating more robust and efficient supply chain operations.

As the Rohingya minority is expelled from their native society, many families have migrated to India where they face societal, legal, and educational discrimination due to lack of transactional relationship with the Indian state. This study aims to understand how the schooling of Rohingya children in the Kalindi Kunj’s Myanmar Refugee Camp in the city of New Delhi (India) is associated with the aspirations of the children and of their parents in the face of cultural disruptions in the socialization of the children. This ethnographical study is based on the narratives of both children and their parents from the Rohingya refugee community as a tool to capture their life-worlds.

The process of chronic pain (CP) and strategies is to improve the patient’s health and well-being. CP is a frequent medical problem that presents a major challenge to healthcare providers because of its complex natural history, imprecise aetiology, and inadequate response to pharmacological treatment. Although different definitions exist it is widely accepted that CP is an ongoing pain that lasts more than 3 months or that persists longer than the reasonably expected healing time for the involved tissues. Also, it is acknowledged that its treatment is much different than the treatment for acute pain. When addressing a person with CP, one should always keep in mind that pain is much more about the individual than the underlying medical condition. Every person is different, and healthcare providers should take a tailor-made approach to managing their pain. This is the only way to ensure good results in pain treatment. Treatment goals should be discussed and adapted to the patient profile. It is fundamental to have clear goals from the beginning and to ensure these are realistic, individualized, and measurable. Effective treatment for CP is only achieved through a holistic framework in which the patient’s well-being is the first concern and an interdisciplinary and societal approach is implemented from the first day.

Changes in eating habits and food preferences caused by circadian rhythm disruptions in shift workers increase the risk for chronic diseases. Several studies demonstrated that shift work exerts adverse effects on various risk factors for cardiometabolic disease and cancer. Moreover, shift work leads to altered eating patterns, including diets low in alkaline foods (such as vegetables, fruit and legumes) and high in acidogenic foods (such as meat, fish and cheese). Previously not examined, this imbalance could result in a high dietary acid load (DAL). DAL has been linked to low-grade metabolic acidosis, tissue inflammation and other metabolic alterations. The aim of this study was to investigate the hypothesis that shift work is positively associated with an increased DAL.

The authors used cross-sectional data from the National Health and Nutrition Examination Surveys (2007–2010). The sample for this analysis was drawn from a representative multistage-probability sample of US civilians. DAL estimations included potential renal acid load (PRAL) and net endogenous acid production (NEAP). Acid load scores and nutrient intake were compared between regular day workers (n = 3,814; mean age, 43.7 ± 0.3; mean body mass index (BMI), 28.6 ± 0.1; females 46.9%) and shift workers (n = 881; age, 37.4 ± 0.6; BMI, 28.4 ± 0.3; females 48.1%). Evening/night shift workers combined with rotating shift workers were contrasted to participants on a regular daytime schedule.

Potassium and magnesium intake were significantly lower in shift workers, whereas no significant differences with regard to total energy intake were found. The authors found significantly higher crude NEAP_F scores in shift workers (mean: 61.8 ± 1.2 mEq/day) compared to regular day workers (mean: 58.7 ± 0.5 mEq/day, P = 0.023). After adjustment for confounders, however, this association remained no longer significant. There were no significant intergroup differences regarding NEAP_R and PRAL_R.

This study revealed significant differences in crude NEAP_F scores between shift workers and day workers. After adjustment for confounders, this association was no longer significant. Such discrepancy is probably because of the scarce homogeneity in the analyzed sample which represents the main limitation of this study. Thus, the results did not confirm the hypothesis that shift work is associated with elevated DAL scores. Importantly, the data suggest significant intergroup differences in nutrient intakes without confirming our initial hypothesis with regard to DAL.

In light of the detrimental health outcomes associated with an increased DAL, this study reinforces the call for evidence-based dietary guidelines in shift workers. Studies in other shift working populations are thus warranted.