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Health literacy is the degree to which individuals have the capacity to obtain, process and understand basic health information and services needed to make appropriate health decisions. The purpose of this paper is to focus on sixth graders’ (N=21, aged 13–14) health literacy, particularly in relation to the rational use of medicines and the role of pharmacies.

The socio-scientific issues (SSI) approach by way of the three-stage model, the stages being scenario, inquiry and decision making, was adopted in this intervention study. The study was a qualitative case study and data consisted of cartoons, audio recordings of group discussions and group interviews. Qualitative data were analyzed using content analysis.

At the beginning of the intervention, pupils possessed detailed information about the rational use of medicines; however, they did not refer to the role of pharmacy as a source of medicine information which they did after the intervention. They were also more aware particularly how to store and dispose of unnecessary medicines. Their theoretical and practical knowledge related to pharmacy careers and production of medicines was enhanced.

The SSI approach by way of the three-stage model provides an excellent opportunity to schools for local co-operation with the community and familiarization with the careers. Moreover, it offers the possibility to enhance pupils’ health literacy.

The SSI approach is so far less implemented in the context of medicine education and to improve health literacy.