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Article
Publication date: 17 November 2011

Update on neuroimaging findings in autism spectrum disorder

Iain Jordan and Declan Murphy

Autism spectrum disorder (ASD) has been studied as a neurodevelopmental disorder since Leo Kanner's early observations of abnormal head circumference in autistic children…

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Abstract

Purpose

Autism spectrum disorder (ASD) has been studied as a neurodevelopmental disorder since Leo Kanner's early observations of abnormal head circumference in autistic children. In the past few years, there has been much progress made in elucidating the anatomical and functional abnormalities in ASD. This paper aims to summarise the extant research.

Design/methodology/approach

This paper provides a summary of relevant research findings in the neuroimaging of autism for the past 12 month period. Papers were identified using the Medline search terms: autism; ASD (functional); magnetic resonance imaging (MRI); neuroimaging; diffusion tensor imaging (DTI); and endophenotype.

Findings

Relatively recent techniques such as functional MRI and DTI have furthered the initial work derived from early histological and structural imaging studies. Even newer techniques, such as DTI tractography and support vector machine analysis, and other computer‐based learning methods have allowed us to move beyond regional variations in grey and white matter volume and study ASD as a disorder of connectivity, and of regional cerebral function and neural circuitry. Brain regions and neural circuits that are implicated in the core symptoms of ASD (deficits in social reciprocity, language and communication, and restricted and stereotyped interests) have been repeatedly shown to be abnormal in those individuals.

Originality/value

This paper aims to provide a background for clinicians to the current research and focuses on developments in the field of neuroimaging of ASD from the past year, which have generated further insights into the neurobiology of ASD.

Details

Advances in Mental Health and Intellectual Disabilities, vol. 5 no. 6
Type: Research Article
DOI: https://doi.org/10.1108/20441281111187162
ISSN: 2044-1282

Keywords

  • Autism spectrum disorders
  • Neuroimaging
  • Endophenotype
  • Neurobiology
  • Functional MRI
  • Diffusion tensor imaging
  • Developmental biology
  • Neurology

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Article
Publication date: 22 October 2019

The role of absorptive capacity within supply chain quality integration

Ziad Alkalha, Iain Reid and Benjamin Dehe

There is a consensus suggesting that the theoretical underpinning associated with supply chain quality management practices remain evolutionary to current thinking…

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Abstract

Purpose

There is a consensus suggesting that the theoretical underpinning associated with supply chain quality management practices remain evolutionary to current thinking. Therefore, this study aims to explore how absorptive capacity (AC) supports supply chain quality integration (SCQI) by building product and process quality within a supply chain (SC).

Design/methodology/approach

A comparative case study of global pharmaceutical manufacturers in a developing market was undertaken. A two-round qualitative research method was designed to collect data through 54 semi-structured interviews with pharmaceutical managers and senior managers.

Findings

The results demonstrate that AC is essential to the development of SCQI because of its ability to use valuable strategic and operational knowledge, which is important when improving consistent internal product and process quality, along with establishing a robust SC design. The authors found that AC enables companies to design their quality and continuously improve their products and processes among their SC members.

Research limitations/implications

The authors acknowledge that these sets of findings are difficult to generalise to other sectors, however, the authors are confident that they can be extrapolated to other companies in the pharmaceutical industry.

Practical implications

The study develops a framework to support practitioners and decision makers to leverage their AC towards facilitating their SCQI practices.

Originality/value

This study explains the role of the AC process in relation to SCQI practices, in the context of the pharmaceutical SC. The study profiles the characteristics of dynamic capabilities to increase the companies’ competencies, processes and resources.

Details

Supply Chain Management: An International Journal, vol. 24 no. 6
Type: Research Article
DOI: https://doi.org/10.1108/SCM-10-2018-0375
ISSN: 1359-8546

Keywords

  • Case studies
  • Developing countries
  • Quality management
  • Supply-chain management
  • Pharmaceuticals
  • Supply chain quality
  • Absorptive capacity
  • Dynamic capability

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Article
Publication date: 1 March 2007

Personality traits of bullies as a contributory factor in workplace bullying: An exploratory study

Elizabeth Seigne, Iain Coyne, Peter Randall and Jonathan Parker

This paper examines the relationship between personality characteristics - as indexed by the ICES Personality Inventory (Bartram, 1994; 1998) and the IBS Clinical…

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Abstract

This paper examines the relationship between personality characteristics - as indexed by the ICES Personality Inventory (Bartram, 1994; 1998) and the IBS Clinical Inventory (Mauger, Adkinson, Zoss, Firestone & Hook, 1980) - and bullying behavior. Although it proved to be difficult to obtain a large enough sample of bullies, the findings indicated that bullies are aggressive, hostile, and extraverted and independent. Furthermore, bullies are egocentric, selfish, and show little concern for the opinions of others. High levels of aggressiveness, assertiveness, competitiveness and independence are traits that are also associated with leadership.

Details

International Journal of Organization Theory & Behavior, vol. 10 no. 1
Type: Research Article
DOI: https://doi.org/10.1108/IJOTB-10-01-2007-B006
ISSN: 1093-4537

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Article
Publication date: 10 May 2011

Leadership effectiveness: the costs and benefits of being emotionally intelligent

Dirk Lindebaum and Susan Cartwright

This paper serves two purposes: first, it is an apology for a failure to produce a planned special issue, along with the rationales as to why the authors decided to…

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Abstract

Purpose

This paper serves two purposes: first, it is an apology for a failure to produce a planned special issue, along with the rationales as to why the authors decided to withdraw it; and second, a commentary on the apparent failure of the research community to address a neglected area of inquiry in emotional intelligence (EI) research.

Design/methodology/approach

The authors provide a commentary.

Findings

The authors draw attention to the possiblity that employing highly emotionally intelligent individuals may not always yield desirable outcomes for organisations, thus seeking to ignite a more balanced debate as to the merits of EI in management and leadership studies. The authors also detail briefly several avenues for future research.

Originality/value

The theme of the planned special issue was situated at the forefront EI research, so this commentary succinctly highlights the theorising that informed the background to it.

Details

Leadership & Organization Development Journal, vol. 32 no. 3
Type: Research Article
DOI: https://doi.org/10.1108/01437731111123924
ISSN: 0143-7739

Keywords

  • Emotional intelligence
  • Leadership
  • Research work
  • Serials

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Article
Publication date: 1 October 1978

Commonplaces

Clive Bingley, Sarah Lawson and Edwin Fleming

WENT TO Brittany in July for a week's holiday with my dear wife, and found it agreeaby empty of both tourists and the flood of crude oil which had enveloped the coast a…

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Abstract

WENT TO Brittany in July for a week's holiday with my dear wife, and found it agreeaby empty of both tourists and the flood of crude oil which had enveloped the coast a few months ago when the tanker Amoco Cadiz broke up. Plenty of rain, though, so we spent the week perambulating between restaurants, and returned lighter of pocket and heavier of tum, to find a charming letter from a librarian in Hong Kong, who said he had met my sister there recently and she had expressed great admiration for me. I replied that in that case it couldn't have been my sister and would he please send a photo of the lady.

Details

New Library World, vol. 79 no. 10
Type: Research Article
DOI: https://doi.org/10.1108/eb038416
ISSN: 0307-4803

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Article
Publication date: 1 August 2004

Political hacktivism: tool of the underdog or scourge of cyberspace?

Caroline Auty

Using the Internet as a means of registering discontent with politicians, policies and groups is a growing phenomenon. There are various ways of manifesting protest on the…

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Abstract

Using the Internet as a means of registering discontent with politicians, policies and groups is a growing phenomenon. There are various ways of manifesting protest on the Internet, including building protest sites, cyber‐squatting, defacing Web sites and organising denial of service attacks. Some of these methods are extremely effective, being cheap to use and requiring limited technical ability. Others err on the wrong side of the law and involve full‐scale hacking. Overall, hacktivism can be a productive part of the political process.

Details

Aslib Proceedings, vol. 56 no. 4
Type: Research Article
DOI: https://doi.org/10.1108/00012530410549240
ISSN: 0001-253X

Keywords

  • Internet
  • Worldwide web
  • Politics

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Article
Publication date: 1 January 2004

Cross‐contamination from raw chicken during meal preparation

Iain Haysom and Kay Sharp

In this study a simple meal was prepared from raw chicken and lettuce in a manner which incorporated examples of common food hygiene malpractice. Prior to meal…

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Abstract

In this study a simple meal was prepared from raw chicken and lettuce in a manner which incorporated examples of common food hygiene malpractice. Prior to meal preparation, the chicken was inoculated with varying levels of Salmonella Typhimurium. The spread of microbial contamination (total viable counts, Enterobacteraceae counts and the presence of Salmonella species) from the chicken to sites in the kitchen was traced. Results indicate how easily bacterial contaminants from food may be spread around a kitchen. Levels of contamination on foods ready for consumption and in areas considered clean after washing up and wiping surfaces are established. These indicate that contaminants are unlikely to be removed from some sites unless cleaning procedures are rigorous.

Details

British Food Journal, vol. 106 no. 1
Type: Research Article
DOI: https://doi.org/10.1108/00070700410515190
ISSN: 0007-070X

Keywords

  • Food safety
  • Contamination
  • Bacteria

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Article
Publication date: 1 April 1966

The Library World Volume 67 Issue 10

IT is seldom that I can bring myself to write anything for publication, and as I had a longish article on “The education of librarians in Great Britain” printed as…

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IT is seldom that I can bring myself to write anything for publication, and as I had a longish article on “The education of librarians in Great Britain” printed as recently as 1964 in the Lucknow Librarian (which is edited by my friend Mr. R. P. Hingorani) I had not contemplated any further effort for some time to come. But as THE LIBRARY WORLD evidently wishes to cover all the British schools of librarianship it would be a pity for Brighton to be left out, even though, coming as it does towards the end of a gruelling series, I can see little prospect of this contribution being read. Perhaps, therefore, I need not apologise for the fact that, as my own life and fortunes have been (and still are) inextricably bound up with those of the Brighton school, any account which I write of the school is bound to be a very personal one.

Details

New Library World, vol. 67 no. 10
Type: Research Article
DOI: https://doi.org/10.1108/eb009506
ISSN: 0307-4803

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Article
Publication date: 1 September 2000

Strategic Issues for Facilities Managers

Martin Fojt

The virtual organization is upon us, or so we are led to believe. No longer will we have to worry about finding enough space for so many workstations, as people will be…

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Abstract

The virtual organization is upon us, or so we are led to believe. No longer will we have to worry about finding enough space for so many workstations, as people will be sitting in cyberspace waiting either to send or receive their next communication. It will not matter where in the universe someone is, provided that they can communicate. People will be working in physical isolation, but this does not matter as they can, yes you’ve guessed it, communicate! There is no doubting that communicating is good and absolutely necessary, but it is quality of communication which is needed, not just any old garbled message. Are standards of communication deteriorating? The media by which we are sending messages are improving, of that there is little doubt, but it is the content and usefulness of this content which must be brought to question.

Details

Facilities, vol. 18 no. 9
Type: Research Article
DOI: https://doi.org/10.1108/02632772200000001
ISSN: 0263-2772

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Article
Publication date: 1 March 2001

Property Journals Index 1990‐2000

K.G.B. Bakewell

Compiled by K.G.B. Bakewell covering the following journals published by MCB University Press: Facilities Volumes 8‐18; Journal of Property Investment & Finance Volumes…

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Abstract

Compiled by K.G.B. Bakewell covering the following journals published by MCB University Press: Facilities Volumes 8‐18; Journal of Property Investment & Finance Volumes 8‐18; Property Management Volumes 8‐18; Structural Survey Volumes 8‐18.

Details

Structural Survey, vol. 19 no. 3
Type: Research Article
DOI: https://doi.org/10.1108/0263080X200100001
ISSN: 0263-080X

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