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Increasing competition in global markets requires many countries to seek new growth sectors. In addition, the nature of competition is changing. This paper applies the business ecosystem concept and studies San Diego as a spatial health and life sciences ecosystem. The purpose of this paper is to identify issues that should be considered in design of innovation policies and regional industry development.

The research approach is built on a literature review of business ecosystems and spatial innovation. The empirical study is based on semi-structured interviews, observations, and information gathering and verification during field research.

The results include a description of the ecosystem structure and dynamics. This paper demonstrates the bottom-up nature of San Diego’s health and life sciences ecosystem without a dominant lead actor, and presents prerequisites for fostering spatial ecosystems.

A single case may not be able to offer a generalized picture of this topic. However, the study raises several considerations for researchers and decision-makers involved in innovation policy design. Future work should extend the study and involve other spatial and substance contexts to compare findings and to pursue a more generic picture of innovation ecosystems and networks.

This paper demonstrates that applying the concept of business ecosystems to the spatial context provides new insights in terms of dynamic mechanisms and factors contributing to economic growth in a particular location. Understanding how to facilitate the creation of successful spatial ecosystems is in the focal point of innovation policies.

The purpose of this paper is to provide a selected bibliography of recent resources on library instruction and information literacy.

Introduces and annotates periodical articles, monographs, and audiovisual material examining library instruction and information literacy.

Provides information about each source, discusses the characteristics of current scholarship, and describes sources that contain unique scholarly contributions and quality reproductions.

The information may be used by librarians and interested parties as a quick reference to literature on library instruction and information literacy.

Convergence in the life sciences and health care industries – the combining of two or more of drugs, diagnostics and devices to create an improved health care product – is leading to new opportunities for business growth and product differentiation. This report aims to examine the issues around convergence, including the drivers, risks and regulatory issues.

This report is based on industry and literature reviews and builds on research carried out by Deloitte Research on the life sciences and health care industry.

The paper finds that technological advances, evolving health care needs and shifting market conditions are creating favourable conditions for convergence. Developing convergent technologies, however, has risks and uncertainties that life sciences companies need to consider along with regulatory issues. Cross‐sector partnerships are becoming more of a necessity and reality for health care firms, who have to be aware of the many operational and ownership issues involved.

Market pressures and opportunities are motivating life sciences firms of all types and sizes to invest in convergence. Convergent technology is transforming cardiovascular care, orthopedic treatment, tissue wound management and other clinical areas by creating solutions that are less invasive, less painful, more patient‐specific, more convenient and sometimes more affordable. Consequently, players from all sectors are entering the competition for R&D assets, setting up new rivalries and alliances.

In mapping the many factors surrounding convergence in the life sciences industry, this report enables firms to evaluate their own opportunities and priorities. It proposes a framework that companies can use to decide which pathway to convergence is best for them.

This chapter introduces readers to a complex adaptive systems approach for integrating research on genes, behavior, and social structures/institutions. Until recently, scientists have resorted to reductionism as a decoding and epistemological strategy for understanding human health. The complex bonds among health’s biological, behavioral, and social dimensions, however, cannot be fully grasped with reductionist schemas. Moreover, because reducing and simplifying can lead to incomplete understanding of phenomena, the resulting deficient knowledge has the potential to be harmful.

To achieve its purpose, this primer will: (1) introduce fundamental notions from complexity science, useful for inquiry and practice integrating research on genes, behavior, and social structures; (2) outline selected methodological strategies employed in studying complex adaptive/dynamic systems; (3) address the question, “Specifically, how can a dynamic systems approach be helpful for integrating research on genes, behavior, and social structures/institutions, to improve the public’s health?”; and (4) provide examples of studies currently deploying a complexity perspective.

The originality/value of this primer rests in its critique of the research status quo and the proposition of an alternative lens for integrating genomic, biomedical, and sociological research to improve the public’s health. The topic of complex adaptive/dynamic systems has begun to flourish within sociology, medicine, and public health, but many researchers lack exposure to the topic’s basic notions and applications.

Modern health care presents challenges for science and technology that go well beyond surgical procedures and physiological monitoring. But although technology is making a rod for policymakers’ backs, it may also be throwing them a lifeline. The research focus is increasingly on information and communications technologies, which are opening up new possibilities in preventive health, self‐diagnosis and even remote surgery. For a public accustomed to paternalistic medicine, the redistribution of R&D resources may come as a shock – but Europe’s overstretched health services need more than sticking plaster solutions.

Big Data analysis is one of the key challenges to the provision of health care to emerge in the last few years. This challenge has been spearheaded by the huge interest in the “4Ps” of health care (predictive, preventive, personalized, and participatory). Big Data offers striking development opportunities in health care and life sciences. Healthcare research is already using Big Data to analyze the spatial distribution of diseases such as diabetes mellitus at detailed geographic levels. Big Data is also being used to assess location-specific risk factors based on data of health insurance claims. Other studies in systems medicine utilize bioinformatics approaches to human biology which necessitate Big Data statistical analysis and medical informatics tools. Big Data is also being used to develop electronic algorithms to forecast clinical events in real time, with the intent to improve patient outcomes and thus reduce costs.

Yet, this Big Data era also poses critically difficult ethical challenges, since it is breaking down the traditional divisions between what belongs to public and private domains in health care and health research. Big Data in health care raises complex ethical concerns due to use of huge datasets obtained from different sources for varying reasons. The clinical translation of this Big Data is thus resulting in key ethical and epistemological challenges for those who use these data to generate new knowledge and the clinicians who eventually apply it to improve patient care.

Underlying this challenge is the fact that patient consent often cannot be collected for the use of individuals’ personal data which then forms part of this Big Data. There is also the added dichotomy of healthcare providers which use such Big Data in attempts to reduce healthcare costs, and the negative impact this may have on the individual with respect to privacy issues and potential discrimination.

Big Data thus challenges societal norms of privacy and consent. Many questions are being raised on how these huge masses of data can be managed into valuable information and meaningful knowledge, while still maintaining ethical norms. Maintaining ethical integrity may lack behind in such a fast-changing sphere of knowledge. There is also an urgent need for international cooperation and standards when considering the ethical implications of the use of Big Data-intensive information.

This chapter will consider some of the main ethical aspects of this fast-developing field in the provision of health care, health research, and public health. It will use examples to concretize the discussion, such as the ethical aspects of the applications of Big Data obtained from clinical trials, and the use of Big Data obtained from the increasing popularity of health mobile apps and social media sites.

Quality, accessible and appropriate housing is key to older people’s ability to live independently. The purpose of this paper is to understand older people’s housing aspirations and whether these are currently being met. Evidence suggests one in five households occupied by older people in England does not meet the standard of a decent home. The Building Research Establishment has calculated that poor housing costs the English National Health Service £1,4bn annually (Roys et al., 2016).

This paper reports on the findings of a participatory theatre approach to engaging with those not often heard from – notably, those ageing without children and older people with primary responsibility for ageing relatives – about planning for housing decisions in later life. The project was led by an older people’s forum, Elders Council, with Skimstone Arts organisation and Northumbria University, in the north east of England.

Findings suggest there is an urgent need to listen to and engage with people about their later life housing aspirations. There is also a need to use this evidence to inform housing, health and social care policy makers, practitioners, service commissioners and providers and product and service designers, to encourage older people to become informed and plan ahead.

Use of a participatory theatre approach facilitated people to explore their own decision making and identify the types of information and support they need to make critical decisions about their housing in later life. Such insights can generate evidence for future housing, social care and health needs. Findings endorse the recent Communities and Local Government (2018) Select Committee Inquiry and report on Housing for Older People and the need for a national strategy for older people’s housing.

Although this call is evidenced through an English national case study, from within the context of global population ageing, it has international relevance.

There is extensive empirical literature that has sought to establish the prevalence of, and risk factors for, loneliness and social isolation in later life. Traditional empirical gerontological approaches have characterised loneliness as a linear experience that is both pathological and easily relieved with external intervention. The purpose of this paper is to explore the potential of qualitative interview data to reveal the possible complexities in understanding loneliness, including conceptual considerations for the dynamic and multi-dimensional aspects of loneliness.

The authors draw on two different studies where the purpose was to qualitatively examine the meaning of loneliness in the lives of older people and how they understood loneliness in the context of their daily life (n=37).

Interviews with “lonely” older people revealed that loneliness is a complex and dynamic experience. The authors also identified a range of internal and external factors that contribute to vulnerability for loneliness as well as resources to alleviate it.

The dynamic and multi-dimensional characteristics of loneliness in older people may help explain why community-based interventions to diminish it may be so challenging.

“Experts by experience' (EBE) involvement in professional health-care education programmes contributes to developing students” caring skills by supporting students’ understanding of the lived experience and reality of service-users’ situations. Also, involvement in health-care education is a beneficial experience for EBEs themselves. This study aims to explore specifically older people’s experiences and perceptions of their involvement of EBE in gerontological education to generate insight into their understanding of this experience.

In this qualitative study, EBEs contributing to delivery of health-care professional education programmes at a UK university took part in focus groups (n = 14) to discuss their views and experiences of involvement in EBE teaching. Data were analysed using open coding.

Four themes emerged from the data, suggesting that older EBEs’ involvement in education may be beneficial for their well-being. The four themes were “contributing to improved care”, “having a purpose”, “being included” and “feeling appreciated”.

Findings support the requirement for nurse educators to develop EBE programmes that involve older people as not only a teaching strategy for students but also a method of promoting the health and well-being of the older EBEs.

There is limited research regarding specifically older EBEs’ experiences of involvement in gerontological education. This is an important area of study because involvement in education may constitute a means of engaging in social, community and voluntary activities for older people, which recent UK health policies advocate as methods of promoting and facilitating healthy ageing.

This discussion paper reviews and critiques literature related to the evolution of the medical humanities as an academic discipline and its contribution to healthcare provision. We argue that despite considerable advances in the field of medical humanities, needs have been identified for a more inclusive, outward‐facing and applied discipline. These needs can be met in the form of what we have called the health humanities, which both embrace interdisciplinarity and engage with the contributions of those marginalised from the medical humanities ‐ for example, allied health professionals, nurses, patients and carers. It is argued that there is a need for new thinking to develop the discipline of health humanities, to develop, provide and share research, expertise, training and education.