Search results
1 – 10 of 49Hadeel Alhazimeh, Mohamed Ghazi Al-Fandi and Lina M.K. Al-Ebbini
Ascorbic acid (AA) is an essential vitamin for human health. Therefore, fast and cost-effective detecting of AA is essential, whether in human or food samples. The purpose of this…
Abstract
Purpose
Ascorbic acid (AA) is an essential vitamin for human health. Therefore, fast and cost-effective detecting of AA is essential, whether in human or food samples. The purpose of this paper is to develop an electrochemical nanosensor for AA detection.
Design/methodology/approach
The proposed nanosensor was developed by printing carbon nanoparticles ink and silver nanoparticles ink on a polydimethylsiloxane (PDMS) substrate. The surface of the PDMS substrate was first treated by corona plasma. Then, the nanomaterials printer was used to deposit both inks on the substrate. The working electrode surface was modified by drop-casting of carbon nanotubes. Morphological evaluation was applied using scanning electron microscopy and cyclic voltammetry. Also, a potentiostat was used to detect AA by differential pulse voltammetry.
Findings
It has been shown that the developed nanosensor linearly worked at a range of (0–5 mM), with a limit of detection lower than 0.8 mM and a relative standard deviation of 6.6%.
Originality/value
The developed nanosensor is characterized by a simple and cost-effective sensing tool for AA. In particular, the nanomaterials enhanced the nanosensor’s sensitivity due to the high catalytic activity.
Details
Keywords
Mohamed Ghazi Al-Fandi, Nid’a Hamdan Alshraiedeh, Rami Joseph Oweis, Rawan Hassan Hayajneh, Iman Riyad Alhamdan, Rama Adel Alabed and Omar Farhan Al-Rawi
This paper aims to report a prototype of a reliable method for rapid, sensitive bacterial detection by using a low-cost zinc oxide nanorods (ZnONRs)-based electrochemical sensor.
Abstract
Purpose
This paper aims to report a prototype of a reliable method for rapid, sensitive bacterial detection by using a low-cost zinc oxide nanorods (ZnONRs)-based electrochemical sensor.
Design/methodology/approach
The ZnONRs have been grown on the surface of a disposable, miniaturized working electrode (WE) using the low-temperature hydrothermal technique. Scanning electron microscopy and energy dispersion spectroscopy have been performed to characterize the distribution as well as the chemical composition of the ZnONRs on the surface, respectively. Moreover, the cyclic voltammetry test has been implemented to assess the effect of the ZnONRs on the signal conductivity between −1 V and 1 V with a scan rate of 0.01 V/s. Likewise, the effect of using different bacterial concentrations in phosphate-buffered saline has been investigated.
Findings
The morphological characterization has shown a highly distributed ZnONR on the WE with uneven alignment. Also, the achieved response time was about 12 minutes and the lower limit of detection was approximately 103 CFU abbreviation for Colony Forming Unit/mL.
Originality/value
This paper illustrates an outcome of an experimental work on a ZnONRs-based electrochemical biosensor for direct detection of bacteria.
Details
Keywords
Nibu Babu Thomas, Lekshmi P. Kumar, Jiya James and Nibu A. George
Nanosensors have a wide range of applications because of their high sensitivity, selectivity and specificity. In the past decade, extensive and pervasive research related to…
Abstract
Purpose
Nanosensors have a wide range of applications because of their high sensitivity, selectivity and specificity. In the past decade, extensive and pervasive research related to nanosensors has led to significant progress in diverse fields, such as biomedicine, environmental monitoring and industrial process control. This led to better and more efficient detection and monitoring of physical and chemical properties at better resolution, opening new horizons in the development of novel technologies and applications for improved human health, environment protection, enhanced industrial processes, etc.
Design/methodology/approach
In this paper, the authors discuss the application of citation network analysis in the field of nanosensor research and development. Cluster analysis was carried out using papers published in the field of nanomaterial-based sensor research, and an in-depth analysis was carried out to identify significant clusters. The purpose of this study is to provide researchers to identify a pathway to the emerging areas in the field of nanosensor research. The authors have illustrated the knowledge base, knowledge domain and knowledge progression of nanosensor research using the citation analysis based on 3,636 Science Citation Index papers published during the period 2011 to 2021.
Findings
Among these papers, the bibliographic study identified 809 significant research publications, 11 clusters, 556 research sector keywords, 1,296 main authors, 139 referenced authors, 63 nations, 206 organizations and 42 journals. The authors have identified single quantum dot (QD)-based nanosensor for biological applications, carbon dot-based nanosensors, self-powered triboelectric nanogenerator-based nanosensor and genetically encoded nanosensor as the significant research hotspots that came to the fore in recent years. The future trend in nanosensor research might focus on the development of efficient and cost-effective designs for the detection of numerous environmental pollutants and biological molecules using mesostructured materials and QDs. It is also possible to optimize the detection methods using theoretical models, and generalized gradient approximation has great scope in sensor development.
Research limitations/implications
The future trend in nanosensor research might focus on the development of efficient and cost-effective designs for the detection of numerous environmental pollutants and biological molecules using mesostructured materials and QDs. It is also possible to optimize the detection methods using theoretical models, and generalized gradient approximation has great scope in sensor development.
Originality/value
This is a novel bibliometric analysis in the area of “nanomaterial based sensor,” which is carried out in CiteSpace software.
Details
Keywords
This paper seeks to consider recent nanosensor developments and the various routes to market through reference to companies which are commercialising these products.
Abstract
Purpose
This paper seeks to consider recent nanosensor developments and the various routes to market through reference to companies which are commercialising these products.
Design/methodology/approach
This paper initially discusses nanosensor markets and applications. It then illustrates progress in commercial exploitation by considering a number of nanosensor companies and their products.
Findings
This paper shows that the commercialisation of nanosensors is still in its infancy but a range of products is now reaching the market. In addition to probes for atomic force and scanning probe microscopy, which presently comprise the bulk of the market, innovative biosensors, gas and chemical sensors are having a growing impact. Many of the supply companies are US‐based with strong links to universities and have frequently raised significant venture finance and subsequent funds from government agencies involved with defence, homeland security and healthcare. Several of the world's large, high‐technology companies are also pursuing nanosensor developments.
Originality/value
This paper provides an insight into the present‐day state of nanosensor commercialisation and gives examples of nanosensor companies and their products.
Details
Keywords
The purpose of this paper is to provide a technical review of recent nanosensor research.
Abstract
Purpose
The purpose of this paper is to provide a technical review of recent nanosensor research.
Design/methodology/approach
This paper describes a number of nanosensor research themes and recent development activities, with an emphasis on work conducted or reported since 2006. It considers a range of emerging nanosensing technologies and two specific areas of application.
Findings
This paper shows that nanosensor technology is developing rapidly and is the subject of a global research effort. Technologies such as nano‐electromechanical system, nano‐opto‐electromechanical system, nanophotonics and the combination of nanotechnology with microtechnology offer prospects to yield sensors for a wide range of chemical, biochemical and physical variables in applications which include healthcare, defence and homeland security, environmental monitoring and light sensing and imaging.
Originality/value
This paper provides a technically detailed, up‐to‐date account of recent nanosensor research.
Details
Keywords
Xingya Wang and Guangchang Pang
This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide readers…
Abstract
Purpose
This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide readers through selecting an appropriate detecting system and signal amplification method according to their research and application purpose.
Design/methodology/approach
This paper classifies the weak interactions between biomolecules, summarizes the common signal amplification methods used in biosensor design and compares the performance of different kinds of biosensors. It highlights a potential electrochemical signal amplification method: the G protein signaling cascade amplification system.
Findings
Developed biosensors which, based on various principles, have their own strengths and weaknesses have met the basic detection requirements for weak interaction between biomolecules: the selectivity, sensitivity and detection limit of biosensors have been consistently improving with the use of new signal amplification methods. However, most of the weak interaction biosensors stop at the research stage; there are only a minority realization of final commercial application.
Originality/value
This paper evaluates the status of research and application of weak interaction biosensors systematically. The G protein signaling cascade amplification system proposal offers a new avenue for the research and development of electrochemical biosensors.
Details
Keywords
This paper aims to describe the nanosensor research reported at the “Nanomaterials: Applications & Properties 2012” conference, held in the Ukraine in September 2012.
Abstract
Purpose
This paper aims to describe the nanosensor research reported at the “Nanomaterials: Applications & Properties 2012” conference, held in the Ukraine in September 2012.
Design/methodology/approach
Following a short overview of the event, this paper describes the nanosensor research reported at the conference, arranged according to the variables involved, i.e. chemical sensing, gas sensors and physical sensing. Brief consideration is also given to developments in power sources.
Findings
This shows that, although nanosensors were not a major theme at the event, several innovative developments for sensing a range of molecular and physical variables were reported.
Originality/value
This paper provides details of the nanosensor research reported at “Nanomaterials: Applications & Properties 2012”.
Details
Keywords
Mehdi Habibi, Yunus Dawji, Ebrahim Ghafar-Zadeh and Sebastian Magierowski
Nanopore-based molecular sensing and measurement, specifically DNA sequencing, is advancing at a fast pace. Some embodiments have matured from coarse particle counters to enabling…
Abstract
Purpose
Nanopore-based molecular sensing and measurement, specifically DNA sequencing, is advancing at a fast pace. Some embodiments have matured from coarse particle counters to enabling full human genome assembly. This evolution has been powered not only by improvements in the sensors themselves, but also in the assisting microelectronic CMOS readout circuitry closely interfaced to them. In this light, this paper aims to review established and emerging nanopore-based sensing modalities considered for DNA sequencing and CMOS microelectronic methods currently being used.
Design/methodology/approach
Readout and amplifier circuits, which are potentially appropriate for conditioning and conversion of nanopore signals for downstream processing, are studied. Furthermore, arrayed CMOS readout implementations are focused on and the relevant status of the nanopore sensor technology is reviewed as well.
Findings
Ion channel nanopore devices have unique properties compared with other electrochemical cells. Currently biological nanopores are the only variants reported which can be used for actual DNA sequencing. The translocation rate of DNA through such pores, the current range at which these cells operate on and the cell capacitance effect, all impose the necessity of using low-noise circuits in the process of signal detection. The requirement of using in-pixel low-noise circuits in turn tends to impose challenges in the implementation of large size arrays.
Originality/value
The study presents an overview on the readout circuits used for signal acquisition in electrochemical cell arrays and investigates the specific requirements necessary for implementation of nanopore-type electrochemical cell amplifiers and their associated readout electronics.
Details
Keywords
Faisal K. Algethami, Hadi M. Marwani, Abdullah M. Asiri and Mohammed M. Rahman
The purpose of this study is to prepare various CeO2-based carbon material (CNT, CB, GO) nanocomposites through a wet chemical process for the development of a sensor probe to…
Abstract
Purpose
The purpose of this study is to prepare various CeO2-based carbon material (CNT, CB, GO) nanocomposites through a wet chemical process for the development of a sensor probe to detect various environmental toxins by using an electrochemical approach under room temperature conditions. A comparative study on sensitive and selective phenolic sensor (4-methoxyphenol; 4-MP) has been fabricated by modifying a glassy carbon electrode (GCE) with various nanocomposites (NCs) such as CeO2, CeO2–CNT (carbon nanotubes), CeO2–CB (carbon black) and CeO2–GO (graphene oxide) NCs.
Design/methodology/approach
The CeO2–CNT NCs were prepared by the wet chemical method at low temperature. NCs were characterized by various methods such as transmission electron microscopy (TEM), Fourier-transform infra-red (FTIR), ultra-violet/visible (UV-Vis) spectroscopy and XRD (X-ray diffraction). CeO2–CNT NCs were immobilized as a film on the flat surface of the GCE by using binders (5% Nafion). The electrochemical measurements of the 4-MP detection with the CeO2–CNT NCs/Nafion/GCE sensor were studied by the current-voltage method.
Findings
In the optimal conditions, the sensitivity, detection limit and limit of quantification of 4-MP sensor probe were found to be 47.56 µAcm-2 µM−1, 12.0 ± 0.2 nM and 40.0 ± 0.5 nM (S/N of 3), respectively.
Research limitations/implications
This electrochemical sensor showed an acceptable analytical performance in the detection of 4-MP with higher sensitivity, lower detection limit, large dynamic concentration range, good reproducibility and fast response time.
Practical implications
This electrochemical approach can be applied practically for the determination of selective 4-MP in real environmental and extracted samples.
Social implications
CeO2–CNT NCs/Nafion/GCE sensor probe was used for the safety of environmental and health-care fields at larger scales.
Originality/value
This electrochemical approach is a significant achievement on the development of sensor probe. The results are indicated as being technically detailed with an up-to-date account of recent chemical sensor research studies.
Details