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The purpose of this paper is to buildup baseline data for ²²⁶Ra, ²³²Th and ⁴⁰K levels in different food samples and computes their cancer risk (CR).

This report has been performed to buildup baseline data for ²²⁶Ra, ²³²Th and ⁴⁰K levels in different food samples and computes their CR. ²²⁶Ra, ²³²Th and ⁴⁰K activity levels were measured using ?-ray spectrometry based on high-purity germanium (HPGe).

The findings exhibited that the annual effective dose (AED) and CR due to ²²⁶Ra ingestion in foodstuff samples have shown the trends cereal > vegetable > meat > fruits > sesame. Meanwhile, (AED) and (CR) due to ⁴⁰K displayed the trends vegetable > cereal > meat > fruits > sesame. Although the average value of radiological dose due to ingestion of some radionuclides slightly exceed the values of some foodstuff around the world. However, the overall average of (AED) for all foodstuff samples (226.6 µSv/y) was found to be far below the world average (AED) (300 µSv/y).

The main contributor to the AED was ⁴⁰K 85, ²²⁶Ra 9 and ²³²Th 6%. The computed magnitude values for CR owing to ²²⁶Ra, ²³²Th, ⁴⁰K (1.3 × 10⁻⁵) lower than International Commission on Radiological Protection (ICRP) CR of (2.5 × 10⁻³) for the general public.

The main contributor to the AED was ⁴⁰K 85 %, ²²⁶Ra 9% and ²³²Th 6%. The computed magnitude values for CR owing to ²²⁶Ra, ²³²Th, ⁴⁰K (1.3 × 10⁻⁵) lower than ICRP CR of (2.5 × 10⁻³) for the general public.

Between 1946 and 1962 the United States detonated 109 nuclear weapons in an area of the Pacific Ocean called the Pacific Proving Grounds, mainly at the Enewetak and Bikini Atolls in the Republic of the Marshall Islands. The British nuclear testing program spanned eleven years (1952-1963) and involved detonation of 21 weapons in addition to a number of smaller-scale experiments (the “minor” trials) in South Australia. In both cases lands that were inhabited by an original people were extensively contaminated by the testing and, following its cessation, these people desired the return of their lands in a condition that would support resumption of traditional lifestyles. Cleanup and reoccupation of the contaminated lands in these two arenas raised similar questions of cultural identity and communication and the importance of cultural as well as technical understanding in establishing conditions for safe resettlement. The approaches taken to resolving these questions in the two situations have been very different—featuring extensive stakeholder involvement in a technocratic decision making process in the Maralinga case and a series of attempted negotiations and claims under the terms of trust agreements with the U.S. government in the Marshall Islands case. Similar questions regarding what constitutes a safe final condition and the means by which safety will be maintained remain in each case however. The Australian case has reached the more definitive outcome of the two. A jointly drafted comprehensive environmental management plan, if fully implemented and sustained over the time periods necessary, could facilitate a semblance of the outstation lifestyle that the aboriginal Maralingan people desire. But what has been agreed to may still prove very difficult to live with given the levels of residual contamination and the many ways that traditional cultural practices put people in intimate contact with the land.

Two-photon polymerization (TPP) has become one of the most popular techniques for stereolithography at very high resolutions. When printing relatively large structures at high resolutions, one of the main limiting factors is the printing time. The purpose of this paper is to present a new slicing algorithm to minimize printing times.

Typically, slicing algorithms used for TPP do not take into account the fact that TPP can print at a range of resolutions (i.e. with different heights and diameters) by varying parameters such as exposure time, laser power, photoresist properties and optical arrangements. This work presents multiresolution layered manufacturing (MLM), a novel slicing algorithm that processes 3D structures to separate parts manufacturable at low resolution from those that require a higher resolution.

MLM can significantly reduce the printing time of 3D structures at high resolutions. The maximum theoretical speed-up depends on the range of printing resolutions, but the effective speed-up also depends on the geometry of each 3D structure.

MLM opens the possibility to significantly decrease printing times, potentially opening the use of TPP to new applications in many disciplines such as microfluidics, metamaterial research or wettability.

There are many instances of previous research on printing at several resolutions. However, in most cases, the toolpaths have to be manually arranged. In some cases, previous research also automates the generation of toolpaths, but they are limited in various ways. MLM is the first algorithm to comprehensively solve this problem for a wide range of true 3D structures.

In this work, a user-friendly Java-based open-source software has been developed for internal radiation dosimetry. Based on values published by the International Commission on Radiological Protection (ICRP), the software calculates the estimated absorbed dose for each organ and also the estimated effective dose, this for about forty of the most known radioactive drugs. In addition, the present software offers many features which include: 1) a very friendly graphical user-interface (GUI) designed to facilitate the process of selecting mandatory input data such as radiopharmaceutical product, administered activity and patient's data, 2) a tool for generating a medical report, which can be exported as PDF file or printed directly and then incorporated into the patient's record, 3) a SQLite database for storing patient's specific and dosimetric data. We believe that the present software can be a useful tool for nuclear medicine workers. It is freely available for download on GitHub (https://github.com/EL-Bakkali-Jaafar/RadioPharmaDose).

This audit was conducted on acute psychiatric in‐patient wards with the aim of establishing if valproate prescribing in acute mania followed evidence‐based guidelines with particular emphasis on formulations used and whether accelerated valproate dosing was employed.

Case notes from 43 (42 percent male) patients admitted with mania and subsequently discharged on valproate were reviewed. Valproate formulation, weight measurement (necessary for dose‐calculation in accelerated dosing), initial valproate dose and increments, serum valproate monitoring and other prescribed psychotropic agents were noted.

Most (95 percent) patients received sodium valproate (epilim chrono/generic), the remaining received valproate semi‐sodium (depakote). All but one patient received antipsychotic medication in combination. Weight was recorded in only four (9 percent) patients. The mean valproate daily dose after the first week was 1,027 mg (sd=408). It took 29 (sd=42) days to reach the maximum daily dose (1,426 mg sd=467) from valproate initiation. Serum levels were monitored in 34 (79 percent) cases, but the mean period between valproate initiation to the first serum level test was 38 (sd=47) days. A significant positive correlation was found between days taken to reach maximum dose and hospital stay (Spearman's rho=0.41, n=43, p=0.006, two‐tailed).

Accelerated valproate dosing was not common practice, which may have resulted in suboptimal efficacy, probably leading to combination treatment.

This study highlights the need for adequate initial dosing and dose increments when treating manic patients and suggests current practice is not evidence‐based. Local prescribing policy and national guidelines' influence on practice are discussed.

Coronavirus disease-2019 (COVID-19) is becoming a crucial health problem worldwide. Continued and high-speed mutations of this virus result in the appearance of new manifestations, making the control of this disease difficult. It has been shown that well-nourished patients have strong immune systems who mostly have short-term hospitalization compared to others. The purpose of this study is to review the major nutrients involved in the immune system reinforcement and to explain nutritional aspects during the recovery of COVID-19.

In this review paper, the mechanistic role of nutrients in boosting the immune system and the nutritional aspects during the recovery of COVID-19 patients were discussed. Papers indexed in scientific databases were searched using antioxidants, COVID-19, inflammation, immune system, macronutrient, micronutrient and probiotic as keywords from 2000 to 2022.

Because of the adverse effects of drugs like thrombosis, pulmonary embolism and hypercholesterolemia, a balanced diet with enough concentrations of energy and macronutrients could increase the patient's durability. The inflammatory cytokines in a vicious cycle delay patients’ rehabilitation. The main mechanistic roles of micronutrients are attributed to the downregulation of virus replication and are involved in energy homeostasis. Dysbiosis is defined as another disturbance among COVID-19 patients, and supplementation with beneficial strains of probiotics helps to exert anti-inflammatory effects in this regard. Being on a well-planned diet with anti-inflammatory properties could reverse cytokine storms as the major feature of COVID-19. Future studies are needed to determine the safe and effective dose of dietary factors to control the COVID-19 patients.

Being on a well-planned diet with anti-inflammatory properties could reverse cytokine storms as the major feature of COVID-19. Future studies are needed to determine the safe and effective dose of dietary factors to control the COVID-19 patients.

Combination of a number of sensors with different response parameters into sensor arrays would enhance the overall performance of the radiation detection system. This paper presents a conceptual approach to the development of sensor arrays system with instantaneous dose and dose rate readout. A dynamic selection of multiple sensors with various sensitivity and accuracy range is implemented by applying pattern recognition (PR) analysis, which maximizes measurement accuracy. A number of relevant PR methods are discussed.

Thick films based on NiO, ZnO, In₂O₃, CeO₂, TiO₂, CuO and CdO are the key sensing elements in the proposed approach. Pure and carbon‐doped metal oxides were screen‐printed on Si wafers to form pn‐heterojunctions. All devices were exposed to a disc‐type 137 Cs source with an activity of 370 kBq. The values of radiation damage of pn‐junctions were estimated from changes in their current‐voltage characteristics.

Sensors showed an increase in the values of current with the increase in radiation dose up to certain levels, exceeding these levels results in unstable dosimetric characteristics.

The sensitivity of metal oxide films to γ‐radiation exposure depends on their composition and thickness. Mixing the oxides in different proportions and the addition of conducting particles, such as carbon, alters films susceptibility to radiation. In particular, sensors based on such films have dose response characteristics with certain level of sensitivity and working dose range, conditioned by particular sensing material properties and the device structure.

Antipsychotic drugs are often used outside their licensed indication to manage aggression in adults with intellectual disabilities in the absence of a diagnosed psychiatric disorder. The current case series shows that antipsychotics could be effective, but they are often used with non‐drug measures and sometimes cause side‐effects. Clinicians did not always carry out a thorough assessment followed by a formulation before prescribing medications, as recommended in the national and international guides (Deb et al, 2009; Unwin & Deb, 2010). It is also apparent that clinicians did not carry out tests to detect side‐effects of risperidone such as metabolic syndrome. Clinicians should use psychotropic medication for a minimum period of time and at the lowest possible dose, and should consider non‐drug management of aggression at the outset and at a regular interval.

Seaweeds are known accumulators of trace elements and edible seaweeds are popular commodities in health food outlets. This particular study covered an area directly affected by discharges from the Dounreay and Sellafield nuclear plants. The results indicate that radionuclide activity levels in Scottish edible seaweeds are low but are marginally high on the north‐west coast than the north‐east. Natural radionuclides are about two orders of magnitude more abundant than those from the nuclear industry. Comparisons were made with Japanese seaweeds: activities were within the same range.

The purpose of this paper is to examine the impact of supplement form and dosage level on consumers’ perceptions of dietary supplement efficacy.

The authors draw upon literature on dietary supplements and accessibility–diagnosticity theory to derive their hypotheses. Hypotheses are tested through two experiments that use a 2 (supplement form: single-ingredient [SI] vs multi-ingredient [MI]) × 2 (dosage level: low vs high) factorial design.

The findings show that consumers perceive that lower dose MI supplements are more effective than lower dose SI supplements, consistent with a “more is better” heuristic. In contrast, under high doses, the supplement form effect is insignificant; that is, MI and SI supplements are perceived to be comparable in terms of efficacy.

Dietary supplements are not regulated the same way as prescription drugs. Consumers often draw inferences about supplement efficacy based on their perceptions rather than objective evidence. This may leave consumers vulnerable to potentially harmful consequences. This research has implications for designing supplement marketing efforts and public policy, which could help consumers to make informed choices when purchasing dietary supplements.

A growing awareness of the importance of maintaining a healthy lifestyle has motivated consumers of all ages to consider alternative remedies, most notably using dietary supplements. Past research offers little insight into understanding consumer reactions to dietary supplement form such as SI and MI supplements and their dosage levels. The studies reported here address this gap in research. Public policy and marketing implications are also discussed.