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The purpose of this paper is to focus on some of the reported natural advanced glycation end‐products (AGE) inhibitors providing an outline of AGE‐breakers and the potential anti‐glycation properties of some foodstuffs.

Literature searches were conducted to find a link between common household spices, medicinal herbs, AGE and diabetes which could lead to practical home‐based recommendations for changes in a person's diet.

Findings tend to indicate the potential of some dietary components to prevent and/or inhibit AGE formation. Thus, these dietary agents may be exploited for controlling AGE‐mediated diabetic pathological conditions and as possible natural protector of AGE formation in vivo. Consequently, the quest for new AGE inhibitors is considered of paramount importance which can be of therapeutic potential in patients with diabetes or age‐related diseases.

Studies on the inhibition of AGE formation have received increasing recognition from both a nutritional and medical research standpoint. Inhibition of the formation of AGE is believed to play a key role in the prevention of diabetic and cardiovascular complications. Investigation of nutritional bioactive compounds with anti‐glycation properties provides future perspectives for prevention or intervention related to AGEs complications.

This paper adds on to the evidence of the use of dietary agents as natural inhibitors of AGE and hence the prevention of diabetic complications and age‐related diseases.

This paper aims to investigate the effect of L-citrulline supplementation on blood pressure (BP) in middle-aged and elderly populations.

Three electronic databases, namely, Google Scholar, PubMed and Scopus, were searched from 1990 to November 2020. Random effects model analysis was applied for quantitative data synthesis, and 6 trials with 150 participants were identified and included in the analysis.

Results showed an overall non-significant effect of L-citrulline supplementation on both systolic BP (SBP) and diastolic BP (DBP) in middle-aged and elderly participants. However, stratified analysis indicated a significant reduction in SBP (SMD: −0.41, 95% CI: −0.84, 0.02; p = 0.06, heterogeneity p = 0.41; I2 = 10%) but not in DBP (SMD:−0.15, 95% CI: −0.57, 0.28; p = 0.51, heterogeneity p = 0.60; I2 = 0%), following longer-term (= 8 weeks) supplementation of L-citrulline. Additionally, higher doses of L-citrulline (= 6 grams) showed a marginally significant reduction in DBP (SMD: −0.38, 95% CI: −0.78, 0.02; p = 0.06, heterogeneity p = 0.50; I2 = 0%).

In conclusion, a higher dosage and longer duration of supplementation with L-citrulline may have potential BP lowering effects in populations at an increased risk of hypertension

Discusses the current situation whereby the majority of elderly people in the UK regularly take at least one prescribed drug and a significant proportion are given long‐term multiple drug therapy. Those in institutions are particularly prone to over‐prescribing. Shows that the rate of prescription is highly significant because large numbers of elderly people have adverse reactions to their medication. In the case of nutritional reactions, the side‐effects of drugs can cause loss of interest in food or precipitate micronutrient deficiencies. Notes that in an elderly person these drug‐diet reactions have considerable knock‐on effects on nutritional status, physical and mental health and immunity to infection. Stresses, therefore, that programmes of drug review and reductions are vital among all elderly people but should be integrated especially into the routines of homes and hospitals

We address the following research questions: (1) Is the innovation trajectory of the acquirer affected by previous acquisitions? (2) In which direction knowledge recombination from the acquisition is pushed further? (3) Is the technological acquisition more a means for knowledge exploration and radical innovation or, on the contrary, a way for consolidating previous technological specialization?

The nature of this study is exploratory; therefore, we opted for an inductive approach based on the L'Oréal case study analysis. Data were triangulated from different sources: (a) the L'Oréal website and press releases collected in the 2009–2015 period; (b) journal articles and books on the global cosmetics industry and the insightful work of Jones (2010); (c) the Questel Orbit database containing data on patents; and (d) the Zephyr – Bureau van Dijk database containing information on the acquisitions of firms.

Empirical evidence from a patent data analysis reveals a paradoxical path. On the one hand, acquisitions enable the company to explore new technological spaces; on the other hand, they allow it to reinforce a preexisting technological trajectory, even when the knowledge base of the target is distant from that of the acquirer. Thus, in our case study, the absorption and recombination of knowledge from a variety of domains support specialization more than diversification technology strategies.

We add to innovation management literature a new perspective, by offering a detailed analysis, through patent data, of the knowledge recombination process, led by technological acquisitions.

The purpose of this study is to determine the physicochemical and rheological parameters of Albizia lebbeck gum.

Physicochemical analysis was carried out using recommended methods. Gas chromatography mass spectrophotometer and Fourier transformed infra red (FTIR) analyses were carried out using their respective spectrophotometer. Scanning electron microscopy was carried out using scanning electron microscope, while rheological measurements were carried out using Ubbelohde capillary viscometer, digital Brookfield DV 1 viscometer and a rheometer.

Albizia zygia gum is an ionic gum with unique physical and chemical properties. Scanning electron micrograph revealed that the internal structure of the gum is porous with irregular molecular arrangement. Thermodynamic parameters of viscous flow indicated the existence of few inter- and intra-molecular interactions, and the attainment of transition state was linked to bond breaking. Coil overlap transition studies revealed the existence of dilute and concentrated regimes. The viscosity of the gum was also found to decrease with decrease in the charge of cation (such that Al3+ > Ca2+ > K+) and with increase in ionic strength.

The paper provided information on physicochemical and rheological characteristics/behaviour of Albizia zygia gum, of Nigerian origin. From this information, possible application of this gum in the food and pharmaceutical industries can be deduced.

The paper is original since information concerning Albizia zygia gum of Nigerian origin are not well documented as established in the work. It also adds values on the use of Albizia zygia gum, either on its own or in combination with other gums for industrial purpose.

This paper aims to evaluate the effect of depolymerised glucomannan in regulating blood lipid and glucose concentrations.

Twenty adult volunteers were recruited. Blood samples were taken at Day 0. The volunteers consumed drinks containing 3.0 g active glucomannan hydrolysates (AMH) for 14 days, after which time blood samples were retaken (Day 15). Blood samples were analysed to determine the blood lipid and glucose concentrations.

The average fasting blood glucose at the start of the trial was 2.54 mmol/L but reduced slightly to 2.49 mmol/L after consumption of the glucomannan. The total average cholesterol at the start of the trial was higher (6.69 mmol/L) than desirable ( < 5.0 mmol/L). This was reduced after consuming the glucomannan to 6.44 mmol/L (3.74 per cent). The triglyceride content was also higher initially than recommended (2.88 mmol/L) but was reduced by 11.5 per cent. The high-density lipoprotein (HDL) was within the desirable range before and after consumption (1.57 and 1.52 mmol/L, respectively), while the average low-density lipoprotein (LDL) was higher than recommended ( < 3.0 mmol/L), representing 4.55 mmol/L and 4.40 mmol/L before and after consumption, respectively. Both parameters were reduced by over 3.0 per cent. The consumption of the glucomannan hydrolysates also reduced the total cholesterol/HDL and LDL/HDL ratios.

The AMH was effective in lowering blood cholesterol and glucose concentrations. Consumption of such carbohydrates could prove useful for these physiological disorders. Further studies are desirable to characterise the exact mechanism.

This paper aims to identify the nature of themes/appeals used in food commercials shown on children’s networks in India. Marketers use various themes/appeals in TV advertisements to influence food consumption habits of children. Children are also found to focus on these appeals while selecting foods rather than using nutritional value as a criteria to select foods.

For the present study, a content analysis of 114 discrete food commercials broadcast on children’s networks was done. These were further analysed to collect data on themes/appeals used in them. SPSS 19.0 was used to record the data and descriptive statistics were used for data analysis.

A majority of food advertisements which were broadcast during children’s programmes included confectionery, ice creams and dairy products, baked products and ready-to-cook food items. Grazing was found to be the most frequently used appeal in these food advertisements. This was followed by taste/flavour/smell/texture, fun/happiness, being “cool”, adult approval/disapproval, family ties and so on. However, a majority of these advertisements did not feature any health-related message.

The study highlights the need for strategic actions by all stakeholders interested in protecting well-being of children. Taking account of the promotional tactics used by food marketers, parents as well as governmental agencies must strongly take steps to check these practices.

As no such study has already been conducted in India (to the best of researcher’s knowledge), this study potentially helps in abridging gaps in literature.

The study aimed to disclose the anti-cancer activity of Pluchea indica tea leaves by evaluating the cytotoxicity on breast and cervical cancer cells, compared with non-cancer cells.

Two P. indica extracts were prepared using two solvents, namely hot water (PA) and ethanol (PE). MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) and clonogenic assays were applied to determine cytotoxic effect of both extracts toward cancer cells from human breast (MDA-MB-231 and MCF7) and cervix (SiHa, HeLa and C-33A) and also non-cancer Vero cells. Dichlorofluorescein diacetate (DCFDA)-staining assay was used to quantify the intracellular level of the reactive oxygen species (ROS). Correlation between the quantity of compounds present and the cytotoxicity of the extracts was analyzed by Pearson's method and a possible class of bioactive compounds was proposed based on the highest correlation coefficient (r).

Significant reduction in cell viability and proliferation capability was observed in all cancer cells after treatment with either PA or PE extract albeit PE was more effective. Lower toxicity was detected in Vero cells, indicating the selectivity and safety of extracts. The intracellular ROS level was augmented in treated cancer cells which were inversely correlated to cell viability, suggesting the cancer toxicity was likely induced by intracellular oxidative stress. As flavonoids were found abundantly in the extracts and flavonoids' content was the most related to the activity (r = 0.815), it was hypothesized that the flavonoids might play crucial roles in cancer cytotoxicity.

P. indica tea-leaf extracts can be a good source of promising anti-cancer agents with reduced side effects for breast and cervical cancer treatment.

The aim of the paper is to present a preliminary study for the design of a new functional food by the incorporation of a collection of ingredients which are all based on an inexpensive by‐product of the food industries: apple pomace. The new product design was considered as a novel gelled dessert formulation which is functional, and totally nature‐based. In fact, the article reviews various raw materials obtainable from the source of apple pomace and gradually supports the hypothesis of such product design.

The current study was designed on the structural basis of paying attention to apple pomace as a byproduct and idea generation for product design, reviewing several ingredients based on apple pomace (available data from the literature) and discussing the suitability of such ingredients for a new functional product. Exclusive attention was made for the development of an apple‐pomace‐based gelled dessert targeting consumers on restricted diets such as diabetics and obese individuals. In these kinds of diets consumption of caloric sweeteners should be abandoned or decreased while increasing the amounts of dietary fibers and polyphenolic compounds can be health‐beneficial.

As an appropriate preliminary formula, amidated low methylester pectins were selected as gelling agents. High methylester pectins, phloridzin and quercetin were used as functional ingredients. Arabinose and fructose were considered as sweetening agents. Also, POPj (phloridzin oxidation product), which is a recently developed natural pigment, was offered as a colouring agent and citric acid for adjusting the pH. Apple specific flavours were also suggested to improve the consumer acceptance of the product. In each case, the evidences of functionalities considered for the target consumers (diabetics and obese individuals) were also discussed.

This fresh formula is novel and can attract both food industry and the consumers because of its natural and functional properties.