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The purpose of this chapter was to develop a framework for comprehensive business diagnostics, which can be integrated into the management of small and medium-sized businesses.

The chapter proposes a multiloop model of comprehensive business diagnostics, which provides the company with timely and objective information about the dynamics of its key performance indicators. The model allows enterprises of the real sector to optimize the information acquiring process with the help of the express diagnostics indicators and ensure the high quality and efficiency of the obtained information. Testing of the multiloop model at the Pavlovo Posad Shawl Manufactory JSC involved three stages: express diagnostics (ED), general diagnostics (GD), and comprehensive diagnostics (CD).

The results determined the need to move to the comprehensive diagnostics (CD) loop of the model. The approbation of the suggested model at the shawl manufacture, particularly the CD loop, allowed the authors to identify the key factors influencing the company's main economic and financial indicators.

The proposed multiloop model can be used at enterprises with different forms of ownership, including small and medium-sized businesses, both in Russia and abroad.

A multiloop model of comprehensive business diagnostics provides managerial staff with qualitative real-time information that helps them make informed and effective management decisions.

The proposed multiloop model allows businesses to acquire data about the dynamics of key indicators, determine the factors' impacts on key financial and economic indicators, and ensure high efficiency of management decisions with minimal cost.

This paper sets out to highlight the problem associated with the development of fieldbus diagnostics in a multi‐vendor environment and to propose a solution based on diagnostic function blocks (FB).

The work focuses on the “master‐slave” communication model in a PROFIBUS fieldbus system, where three different vendor solutions are investigated.

Although the fieldbus standards specify the type and format of the diagnostics data, the extent, location and sequence of diagnostics data within a controller are entirely vendor‐dependent. The outcome from this work defines a framework for representing the diagnostics data in the context of a special function block.

This research work defines a novel unified framework for representing the fieldbus diagnostics data using FB for multi‐vendor solutions in a PROFIBUS environment.

An important current trend in health care is the move toward personalized medicine. Personalized medicine includes diagnostic and therapeutic interventions, with risk defined through genetics. The key paradigm shift brought about by the advent of personalized medicine is the increased use of in vitro genomic diagnostics. These tests offer the potential of being able to predict which patients are likely to respond to a particular drug, or which patients are likely to develop adverse reactions to a drug. The focus of this paper is the use of genomic diagnostics, and how the increasing development and translation into clinical practice of diagnostic – drug combination products will be adopted into health care delivery. The meaning of value and how to measure it is considered from different perspectives. A novel framework for evaluating the value of genomic diagnostics is proposed. Finally, the implications for regulatory approval and policy are discussed using an illustrative case study.

The Global Health Initiative (GHI) is a tripartite collaboration among Northwestern University, non-profit donors, and commercial diagnostics companies. GHI attempts to bridge the gap between the market for sophisticated medical diagnostics equipment in wealthy nations and the need for point-of-care diagnostics in resource limited settings. In 2006 GHI narrowed its focus to HIV diagnostics for underserved nations. The case examines the accuracy-access tradeoff related to the roll-out of infant HIV diagnostics in Tanzania. Tanzania has a prevalent HIV/AIDS problem, particularly in children. As of 2007, Tanzania had an estimated 140,000 children infected with HIV. Existing lab-based diagnostic equipment was either inaccurate for use in infants or required highly skilled health workers. Tanzania's limited infrastructure also forced healthcare providers to choose between providing advanced care to a minority of the population and offering minimal care to the majority with poor access. A Kellogg MBA student research team performed more than thirty in-country interviews to collect data on stakeholder perceptions of three infant test concepts: the strip test, the squeeze test, and the filter paper test. Across the three tests, access decreased as accuracy increased---rural labs could not find or afford health workers skilled enough to conduct the test. In general, interviewees closely affiliated with the government preferred accuracy over access. In contrast, private health facilities had to follow fewer regulations and preferred access over accuracy. The case focuses on the decisions facing Kara Palamountain, the executive director of GHI, in her roll-out recommendations for infant HIV tests in Tanzania. It examines key factors of working in a developing country, including the need to operate in the absence of sufficient market research, balance the competing agendas of different stakeholders, and mitigate external risks such as major international funding.

This case was written to be used as a teaching case for students unfamiliar with how to approach and analyze a typical business school case. Unlike many cases used in specific classroom settings, this case is intended to be broad enough that any single student will not have a significant advantage because of his or her background. Moreover, the case is designed to guide students' thinking in a certain direction, using open-ended and more focused discussion questions provided at the case's end.

The purpose of this paper is to establish the value of clinical genetic diagnostics in the lives of people with an intellectual disability (ID), their families, and their primary and professional caregivers. It has been shown that psychologists are more likely to make use of the opportunities offered by clinical genetic diagnostics if they have seen the psychological benefits in their own practice. Moreover, this paper aims to promote the practice of informing people with ID, their families, and other caregivers regarding the current technological advances in genetic diagnostics, thereby allowing these patients to decide for themselves whether to utilise these opportunities.

The authors report four case studies in which the psychosocial value to each patient is pivotal.

In these four cases, it is clear the medical model can augment the social model by providing an interpretation of its meaningfulness in the lives of the people concerned.

Case studies alone can have limited scientific significance. This approach examining the significance of clinical genetic diagnosis should be studied further in larger groups.

It is hoped that psychologists and other professional caregivers will become enthused about the value of clinical genetic diagnostics and will choose to discuss the option of referral for clinical genetic diagnostics with their patients more often.

People with an ID who are seeking mental health care, and their caregivers, should be given the opportunity to take part in the decision regarding whether to use clinical genetic diagnostics, which may even have a destigmatising effect.

Quality of life may improve for people with an ID seeking mental healthcare and for their caregivers as well by opening up discussion regarding the opportunities presented by clinical genetic diagnostics. The fact that people are able to make their own choices based on their own considerations can have a destigmatising effect.

To provide original knowledge for graduate students, research workers and specialists in ability maintenance system of engineering systems in range of improving their diagnostic susceptibility in order to improve of credibility of worked out diagnosis, genesis and forecast.

In this work are methodological guidelines to realize a process of improving of diagnostic susceptibility of engineering systems, which can be approached as an automatics system. It can be hydraulic, pneumatic and fuel systems, oil and gas pipelines, etc.

It was noticed and next theoretically and experimentally confirmed that signals of weak interactions, which can excite between a tested object (hydraulic system) and a adjoined testing object (a corrector), are an additional piece of diagnostic information. This information allows for an increase of reliability of diagnosis, which is working out.

The signals of weak interactions can arise, when a tested object can be approached as an automatic control system (ACS), in which can be distinguished a controlled system (e.g. installation) and a control unit (e.g. pump). Experimental research was realized on a physical model of the airplane hydraulic installation. Other object requires similar investigations.

The development of functional (parametric and signal‐based) diagnosing methods. The proposition of “signal‐based diagnostics” based on the indicators of quality of course signal. These indicators result from the principles of the automatics, and from parametric diagnostics, resulting from the principles of the static and dynamic identification of diagnosing objects.

The proposition of receiving diagnostic information, also during observation of phenomena, which occur in a feedback path of automatics systems, in which operates a specially adjoined corrector (a testing object). Such approach allows by means of change of corrector's parameters to determine optionally a required sensitivity of measuring system, and to control a set value into the corrector, which is an output signal in the occurring in the past.

The Global Health Initiative (GHI) is a tripartite collaboration among Northwestern University, non-profit donors, and commercial diagnostics companies. GHI attempts to bridge the gap between the market for sophisticated medical diagnostics equipment in wealthy nations and the need for point-of-care diagnostics in resource limited settings. In 2006 GHI narrowed its focus to HIV diagnostics for underserved nations. The case examines the accuracy-access tradeoff related to the roll-out of infant HIV diagnostics in Tanzania. Tanzania has a prevalent HIV/AIDS problem, particularly in children. As of 2007, Tanzania had an estimated 140,000 children infected with HIV. Existing lab-based diagnostic equipment was either inaccurate for use in infants or required highly skilled health workers. Tanzania's limited infrastructure also forced healthcare providers to choose between providing advanced care to a minority of the population and offering minimal care to the majority with poor access. A Kellogg MBA student research team performed more than thirty in-country interviews to collect data on stakeholder perceptions of three infant test concepts: the strip test, the squeeze test, and the filter paper test. Across the three tests, access decreased as accuracy increased---rural labs could not find or afford health workers skilled enough to conduct the test. In general, interviewees closely affiliated with the government preferred accuracy over access. In contrast, private health facilities had to follow fewer regulations and preferred access over accuracy. The case focuses on the decisions facing Kara Palamountain, the executive director of GHI, in her roll-out recommendations for infant HIV tests in Tanzania. It examines key factors of working in a developing country, including the need to operate in the absence of sufficient market research, balance the competing agendas of different stakeholders, and mitigate external risks such as major international funding dry

This case was written to be used as a teaching case for students unfamiliar with how to approach and analyze a typical business school case. Unlike many cases used in specific classroom settings, this case is intended to be broad enough that any single student will not have a significant advantage because of his or her background. Moreover, the case is designed to guide students' thinking in a certain direction, using open-ended and more focused discussion questions provided at the case's end.

To emphasise the need for remote fieldbus diagnostics and to show a technical solution based on industry standard approaches.

The design and approach takes a Profibus fieldbus, as an example candidate, and captures the diagnostic data using an OPC model and then uses a Java RMI object broker to develop/support the remote end clients.

The findings show, by an implementation example, that it is possible to implement remote diagnostics for a fieldbus network, without interfering with the operation of the network. The findings also highlight the need for security in such a solution.

The implementation example is rather cumbersome, but the paper suggests that all the hardware and software could be implemented on a single embedded processor in a single box. The security issues are flagged as a possible limitation, but solution approaches are briefly suggested.

The paper highlights the lack of standardisation around fieldbus diagnostics. Even for the same fieldbus type, different manufacturers will use different diagnostic protocols and codes. This paper suggests a practical implementation, where the diagnostic codes can be interpreted a fixed stage and presented to an end client in a consistent manner.

This work is based on a two year original research project. The solution makes heavy use of industry standard protocols but the work is original.

Condition monitoring is an important aspect of the maintenance program for rotating machines. The vibration signature is usually analyzed to perform diagnostics of the health of the machine. The data acquisition and analysis were cumbersome in the analog era and dedicated instruments were required and the diagnostics was usually a laboratory‐based exercise and time consuming. With the advent of high‐speed microprocessors, the practice has completely changed. A modern continuous condition monitoring and diagnostics system is first described. With the recent advances in Internet‐based technologies, the condition monitoring procedures are poised for a quantum jump in the way the machines can be maintaned continuously on‐line at remote locations or checked through the Web for any faults. A specific example of the design of an Applet towards this goal is described in this paper.