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Three-dimensional (3D) printing technologies have gained attention in dentistry because of their ability to print objects with complex geometries with high precision and accuracy, as well as the benefits of saving materials and treatment time. This study aims to explain the principles of the main 3D printing technologies used for manufacturing dental prostheses and devices, with details of their manufacturing processes and characteristics. This review presents an overview of available 3D printing technologies and materials for dental prostheses and devices.

This review was targeted to include publications pertaining to the fabrication of dental prostheses and devices by 3D printing technologies between 2012 and 2021. A literature search was carried out using the Web of Science, PubMed, Google Scholar search engines, as well as the use of a manual search.

3D printing technologies have been used for manufacturing dental prostheses and devices using a wide range of materials, including polymers, metals and ceramics. 3D printing technologies have demonstrated promising experimental outcomes for the fabrication of dental prostheses and devices. However, further developments in the materials for fixed dental prostheses are required.

3D printing technologies are effective and commercially available for the manufacturing of polymeric and metallic dental prostheses. Although the printing of dental ceramics and composites for dental prostheses is promising, further improvements are required.

This study aims to compare the marginal fit, flexural strength and hardness for a ceramic premolar that is constructed using dental computer aided machining (CAM) and three-dimensional slurry printing (3DSP).

Dental CAM and 3DSP are used to fabricate a premolar model. To reduce the fabrication time for 3DSP, a new composition of solvent-free slurry is proposed. Before it is fabricated, the dimensions of the green body for the premolar model are enlarged to account for the shrinkage ratio. A two-stage sintering process ensures accurate final dimensions for the premolar model. The surface morphology of the green body and the sintered premolars that are produced using the two methods is then determined using scanning electronic microscopy. The sintered premolars are seated on a stone model to determine the marginal gap using an optical microscope. The hardness and the flexural strength are also measured for the purpose of comparison.

The developed solvent-free slurry for 3DSP can be used to produce a premolar green body without micro-cracks or delamination. The maximal marginal gap for the sintered premolar parts that are constructed using the green bodies from dental CAM is 98.9 µm and that from 3DSP is 72 µm. Both methods produce a highly dense zirconia premolar using the same sintering conditions. The hardness value for the dental CAM group is 1238.8 HV, which is slightly higher than that for the 3DSP group (1189.4 HV) because there is a difference in the pre-processing of the initial ceramic materials. However, the flexural strength for 3DSP is 716.76 MPa, which is less than the requirement for clinical use.

This study verifies that 3DSP can be used to fabricate a zirconia dental restoration device that is as good as the one that is produced using the dental CAM system and which has a marginal gap that is smaller than the threshold value. The resulting premolar restoration devices that are produced by sintering the green bodies that are produced using 3DSP and dental CAM under the same conditions have a similar hardness value, which is four times greater than that of enamel. The flexural strength of 3DSP does not meet the requirement for clinical use.

The purpose of this paper is to outline and prioritizes risk sources in medical device development (MDD) process using an integrated “structural equation modeling” (SEM) and fuzzy “technique for order performance by similarity to ideal solution (TOPSIS)” framework.

Risk sources which deter MDD process are explored through literature review. Initial structural model is proposed, factor loadings are determined by exploratory factor analysis and model fit is established by confirmatory factor analysis. Further, the sources are ranked using FTOPSIS, and sensitivity analysis is carried to check robustness of results.

The sources of risks have catastrophic effect on MDD process. The initial SEM model developed based on survey of experts is found reliable and valid which breaks up the risk sources into three categories – internal sources of risks, user-related sources of risks and third-party-related sources of risks. The risk sources are ranked and prioritized based on perspective of experts from the categories using FTOPSIS; unmet user needs/requirements is found as the most important source of risk. Results of sensitivity analysis confirm that the factors are relatively less sensitive to criteria weights confirming reliability of initial solution.

The proposed methodology combines qualitative and quantative approaches, making it little complex and lengthy, but results in dual confirmation.

The outcomes of this research will be of prime use for MDD industries to mitigate risk sources. It will help to increase the success rate of MDD.

Integrated SEM-FTOPSIS provides a unique and effective structural modeling-based decision support tool. The framework can be effectively utilized in other domains, and failure events of medical devices can be potentially controlled by applying risk mitigation measures.

This study aims to provide an overview of rapid prototyping (RP) and shows the potential of this technology in the field of medicine as reported in various journals and proceedings. This review article also reports three case studies from open literature where RP and associated technology have been successfully implemented in the medical field.

Key publications from the past two decades have been reviewed.

This study concludes that use of RP-built medical model facilitates the three-dimensional visualization of anatomical part, improves the quality of preoperative planning and assists in the selection of optimal surgical approach and prosthetic implants. Additionally, this technology makes the previously manual operations much faster, accurate and cheaper. The outcome based on literature review and three case studies strongly suggests that RP technology might become part of a standard protocol in the medical sector in the near future.

The article is beneficial to study the influence of RP and associated technology in the field of medicine.

The potential implications of the three-dimensional printing (3DP) technology are growing enormously in the various health-care sectors, including surgical planning, manufacturing of patient-specific implants and developing anatomical models. Although a wide range of thermoplastic polymers are available as 3DP feedstock, yet obtaining biocompatible and structurally integrated biomedical devices is still challenging owing to various technical issues.

Polyether ether ketone (PEEK) is an organic and biocompatible compound material that is recently being used to fabricate complex design geometries and patient-specific implants through 3DP. However, the thermal and rheological features of PEEK make it difficult to process through the 3DP technologies, for instance, fused filament fabrication. The present review paper presents a state-of-the-art literature review of the 3DP of PEEK for potential biomedical applications. In particular, a special emphasis has been given on the existing technical hurdles and possible technological and processing solutions for improving the printability of PEEK.

The reviewed literature highlighted that there exist numerous scientific and technical means which can be adopted for improving the quality features of the 3D-printed PEEK-based biomedical structures. The discussed technological innovations will help the 3DP system to enhance the layer adhesion strength, structural stability, as well as enable the printing of high-performance thermoplastics.

The content of the present manuscript will motivate young scholars and senior scientists to work in exploring high-performance thermoplastics for 3DP applications.

Although many researchers have widely studied additive manufacturing (AM) as one of the most important industrial revolutions, few have presented a bibliometric analysis of the published studies in this area. This paper aims to evaluate AM research trends based on 4607 publications most cited from year 2010 to 2020.

The research methodology is bibliometric indicators and network analysis, including analysis based on keywords, citation analysis, productive journal, related published papers and authors indicators. Two free available software were employed VOSviewer and Bibexcel.

Keywords analysis results indicate that among the AM processes, Selective Laser Melting and Fused Deposition Modeling techniques, are the two processes ranked on top of the techniques employed and studied with 35.76% and 20.09% respectively. The citation analysis by VOSviewer software, reveals that the medical applications field and the fabrication of metal parts are the areas that interest researchers greatly. Different new research niches, as pharmaceutical industry, digital construction and food fabrication are growing topics in AM scientific works. This study reveals that journals “Materials & design”, “Advanced materials”, “Acs applied materials & interfaces”, “Additive manufacturing”, “Advanced functional materials” and “Biofabrication” are the most productive and influential in AM scientific research.

The results and conclusions of this work can be used as indicators of trends in AM research and/or as prospects for future studies in this area.

This paper aims to provide an overview of applications of medical rapid prototyping (MRP)-assisted customized surgical guides (CSGs) and shows the potential of this technology in complex surgeries. This review paper also reports two case studies from open literature where MRP-assisted CSGs have been successfully used in complex surgeries.

Key publications from the past two decades have been reviewed.

This study concludes that the use of MRP-assisted CSGs improves the accuracy of surgery. Additionally, MRP-assisted CSGs make the surgery much faster, accurate and cheaper than any other technique. The outcome based on literature review and two case studies strongly suggested that MRP-assisted CSGs might become part of a standard protocol in the medical sector to operate the various complex surgeries, in the near future.

Advanced technologies like radiology, image processing, virtual surgical planning (VSP), computer-aided design (CAD) and MRP made it possible to fabricate the CSGs. MRP-assisted CSGs can easily transfer the VSP into the actual surgery.

This paper is beneficial to study the development and applications of MRP-assisted CSGs in complex surgeries.

Medical technology (MedTech) is a growth industry, which like other manufacturing sectors has undergone fragmentation of production and emergence of Global Value Chains (GVCs). The purpose of this paper is to compare how two open European economies position themselves competitively within MedTech GVCs: highly developed Switzerland and the emerging Czech Republic.

The research applies a mixed methodology to analyze the performance of each location in the MedTech GVCs. It draws on macroeconomic, industry, trade and a proprietary sample of firm data, combined with onsite interviews.

The economic outcomes and GVC positions differ in both cases, whereas Switzerland focuses on high value-added activities such as R&D and after-sales service. Specialized manufacturing is also located here in spite of high costs. By contrast, the Czech Republic focuses mostly on low value-added activities, like manufacturing disposables, although some domestic innovative companies are notable. The authors generalize four types of firms in the industry, comparing their presence in both locations.

The competitive positions and challenges faced by each location when engaging in MedTech GVCs are summarized and related to economic outcomes. In the Czech Republic, the barriers to upgrading include its business environment, and weak links between education institutions and industry. Switzerland’s high cost structure is offset by adding high value in core competencies. Both countries should protect the inherent advantage their locations offer within responsive European supply chains.

GVC research in the MedTech sector has been limited. There is no comparison of two European countries, and their position in MedTech GVCs, nor of how firms, participate successfully in them.

The use of removable complete dentures is a selectable restorative procedure for edentulous patients. To improve the fabrication quality and efficiency of removable complete dentures, this paper aims to introduce a new method to fabricate customized wax complete dentures with additive manufacturing. This process uses complementary digital technologies, and allows faster and better manufacture of complete dentures.

In the study, a dental scanner was used to obtain surface data from edentulous casts and rims made by the dentist. A parameterized three-dimensional graphic database of artificial teeth was pre-established. Specialized computer-aided design software was used to set up the artificial dentition and design the esthetic gingiva and base plate. A selective laser sintering machine was used to transfer the data from stereolithography files into a wax base plate with location holes for each artificial tooth.

Under this method, a set of wax base plates with 28 location holes available for the placement of the artificial teeth were designed and fabricated within 6 h. The try-in wax dentures fitted the patient’s mouth well, besides occlusion relationships. Then, the occlusion relationships can be adjusted manually to achieve a balanced centric occlusion.

This method can be used to design and fabricate wax try-in removable complete dentures semi-automatically and rapidly; however, the algorithm for the occlusion contact design needs to be improved.

This paper aims to obtain a texture dental model with real images and improve the rendering effect of the dental model.

The paper proposes a semiautomatic method to construct a realistic dental model with real images based on two-dimensional/three-dimensional (2D/3D) registration. First, a 3D digital dental model and three intraoral images are obtained by a 3D scanner and digital single-lens reflex camera. Second, the camera projection poses for every intraoral images are calculated by using the single-objective optimization algorithm. Third, with camera poses, the preliminary projection texture mapping is performed; besides, the seam between two textures is marked. Finally, the marked regions are fused based on the image pyramid to eliminate obvious seams.

The paper provides a method to construct a realistic dental model. The method can map three intraoral images to the dental model. The experimental results show that the textured dental model without obvious distortion, dislocation and seams is constructed with simple interactions.

The proposed method can be applied to the digital smile design system to improve the communication efficiency between doctors, patients and technicians.