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This study examines the impact of university science parks’ (USPs) capabilities on revenue generation and introduces regional innovation as a moderating variable. This study aims to provide insights into enhancing revenue generation and fully leveraging the role of USPs in promoting revenue generation.

This study employs system generalized method of moments (GMM) estimation for 116 universities in China from 2008 to 2020, using hierarchical regression analysis to examine the relationships between variables.

The findings suggest that USPs play a beneficial role in fostering revenue generation. Specifically, the provision of incubation funding demonstrates a positive correlation, while USPs size exhibits an inverted U-shaped pattern, with a threshold at 3.037 and a mean value of 3.712, highlighting the prevalent issue of suboptimal personnel allocation in the majority of USPs. Moreover, the analysis underscores the critical moderating influence of regional innovation, affecting the intricate interplay between USPs size, incubation funding and revenue generation.

The single country (China) analysis relied solely on the use of secondary data. Future studies could expand the scope to include other countries and employ primary data collection. For instance, future research can further examine how regional development and USPs strategic plan impact revenue generation.

The study recommends that USPs managers and policymakers recognize the importance of incubation funding and determine the optimal quantity of USPs size to effectively foster revenue generation in USPs. Policymakers can use regional innovation as a moderating variable to reinforce the relationship between USPs size and incubation funding on revenue generation.

The study’s findings can contribute to the strategic industry growth and economic development of nations by promoting revenue generation. Leveraging the role of USPs and implementing the study’s recommendations can strengthen innovation and technology capabilities, driving strategic industry growth and economic development. This can enhance global competitiveness and promote sustainable economic growth.

This study introduces regional innovation as a moderating variable and provides empirical evidence of its influence on the relationship between USPs size and incubation funding on revenue generation. This adds value to research to the existing literature on USPs and revenue generation by showcasing the importance of examining the regional impact in research and innovation.